JPS57108017A - Antithrombotic agent - Google Patents
Antithrombotic agentInfo
- Publication number
- JPS57108017A JPS57108017A JP18446780A JP18446780A JPS57108017A JP S57108017 A JPS57108017 A JP S57108017A JP 18446780 A JP18446780 A JP 18446780A JP 18446780 A JP18446780 A JP 18446780A JP S57108017 A JPS57108017 A JP S57108017A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- antithrombotic agent
- salt
- prepared
- active component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To provide an antithrombotic agent having blood platelet coagulation suppressing activity and low toxicity, by using 1,2-benzisothiazol-3-one derivative or its salt as an active component.
CONSTITUTION: An antithrombotic agent of the form of tablet, powder, capsule, injection, etc. is prepared by using the compound of formulaI(R is H or CH3) or its salt as active component. Since the compound of formulaIis a safe compound having extremely high LD50, it can be administered at a considerably high dose, and its minimum effective dose is 10W500mg per dose for adult. The compound of formulaIwherein R is CH3 is a novel compound which can be prepared by dispersing the compound of formula II in dried CCl4, adding dried chlorine to the dispersion until the dispersion is converted to a complete solution, adding the compound of formula III obtained by the above reaction dropwise to isopropanolamine dissolved in methylene chloride, and reacting the components.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18446780A JPS57108017A (en) | 1980-12-25 | 1980-12-25 | Antithrombotic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18446780A JPS57108017A (en) | 1980-12-25 | 1980-12-25 | Antithrombotic agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57108017A true JPS57108017A (en) | 1982-07-05 |
JPH0129771B2 JPH0129771B2 (en) | 1989-06-14 |
Family
ID=16153658
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18446780A Granted JPS57108017A (en) | 1980-12-25 | 1980-12-25 | Antithrombotic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57108017A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58177982A (en) * | 1982-04-09 | 1983-10-18 | Green Cross Corp:The | Benzoisothiazoline derivative and antitrichophytic |
-
1980
- 1980-12-25 JP JP18446780A patent/JPS57108017A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58177982A (en) * | 1982-04-09 | 1983-10-18 | Green Cross Corp:The | Benzoisothiazoline derivative and antitrichophytic |
Also Published As
Publication number | Publication date |
---|---|
JPH0129771B2 (en) | 1989-06-14 |
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