JPS57108017A - Antithrombotic agent - Google Patents

Antithrombotic agent

Info

Publication number
JPS57108017A
JPS57108017A JP18446780A JP18446780A JPS57108017A JP S57108017 A JPS57108017 A JP S57108017A JP 18446780 A JP18446780 A JP 18446780A JP 18446780 A JP18446780 A JP 18446780A JP S57108017 A JPS57108017 A JP S57108017A
Authority
JP
Japan
Prior art keywords
compound
antithrombotic agent
salt
prepared
active component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP18446780A
Other languages
Japanese (ja)
Other versions
JPH0129771B2 (en
Inventor
Koji Yamada
Tamotsu Hashimoto
Masaori Naruse
Yu Murayama
Hideki Shinno
Takeshi Ono
Akio Nakamizo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PAAMAKEMU ASIA KK
Permachem Asia Ltd
KH Neochem Co Ltd
Original Assignee
PAAMAKEMU ASIA KK
Kyowa Hakko Kogyo Co Ltd
Permachem Asia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PAAMAKEMU ASIA KK, Kyowa Hakko Kogyo Co Ltd, Permachem Asia Ltd filed Critical PAAMAKEMU ASIA KK
Priority to JP18446780A priority Critical patent/JPS57108017A/en
Publication of JPS57108017A publication Critical patent/JPS57108017A/en
Publication of JPH0129771B2 publication Critical patent/JPH0129771B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To provide an antithrombotic agent having blood platelet coagulation suppressing activity and low toxicity, by using 1,2-benzisothiazol-3-one derivative or its salt as an active component.
CONSTITUTION: An antithrombotic agent of the form of tablet, powder, capsule, injection, etc. is prepared by using the compound of formulaI(R is H or CH3) or its salt as active component. Since the compound of formulaIis a safe compound having extremely high LD50, it can be administered at a considerably high dose, and its minimum effective dose is 10W500mg per dose for adult. The compound of formulaIwherein R is CH3 is a novel compound which can be prepared by dispersing the compound of formula II in dried CCl4, adding dried chlorine to the dispersion until the dispersion is converted to a complete solution, adding the compound of formula III obtained by the above reaction dropwise to isopropanolamine dissolved in methylene chloride, and reacting the components.
COPYRIGHT: (C)1982,JPO&Japio
JP18446780A 1980-12-25 1980-12-25 Antithrombotic agent Granted JPS57108017A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP18446780A JPS57108017A (en) 1980-12-25 1980-12-25 Antithrombotic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18446780A JPS57108017A (en) 1980-12-25 1980-12-25 Antithrombotic agent

Publications (2)

Publication Number Publication Date
JPS57108017A true JPS57108017A (en) 1982-07-05
JPH0129771B2 JPH0129771B2 (en) 1989-06-14

Family

ID=16153658

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18446780A Granted JPS57108017A (en) 1980-12-25 1980-12-25 Antithrombotic agent

Country Status (1)

Country Link
JP (1) JPS57108017A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58177982A (en) * 1982-04-09 1983-10-18 Green Cross Corp:The Benzoisothiazoline derivative and antitrichophytic

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58177982A (en) * 1982-04-09 1983-10-18 Green Cross Corp:The Benzoisothiazoline derivative and antitrichophytic

Also Published As

Publication number Publication date
JPH0129771B2 (en) 1989-06-14

Similar Documents

Publication Publication Date Title
JPS5671073A (en) Imidazole derivative
ES8306371A1 (en) Stable S-adenosylmethionine salts, the process for their preparation and therapeutic compositions which contain them as active principle.
FR2420344A1 (en) NEW OXIME-ETHERS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
JPS57109721A (en) Carcinostatic agent
JPS5489036A (en) Remedy and preventive for hypersensitivity to light
JPS5646810A (en) Blood platelet coagulation inhibitor
HU903092D0 (en) Process for the preparation of buten-carboxylic acid derivatives and pharmaceutical compositions containing such compounds
JPS57108017A (en) Antithrombotic agent
IE821258L (en) Anti-herpes medicaments
JPS5630917A (en) Preventive and remedy for hepatitis
JPS5735515A (en) Immunoregulating agent
JPS57140716A (en) Antiallergic agent
ES8303393A1 (en) Ascorbic acid derivatives.
JPS57108016A (en) Antithrombotic agent
EP0098972A3 (en) 5-phenoxybenzisothiazole-4'-urea derivatives, process for their preparation and their use as herbicides
FI862636A (en) PHARMACEUTICAL COMPOSITES WITH NEUROLEPTIC EFFECTS FOR FRUIT FRAMSTAELLNING.
JPS5742620A (en) Novel antiulcer agent
JPS57108014A (en) Antithrombotic agent
JPS5731616A (en) Relaxing agent for muscle comprising benzofurancarboxylic acid amide
JPS54125663A (en) Carcinostatic agent and novel compound having carcinostatic activity
JPS5455562A (en) Lactam compound
JPS53124267A (en) 1-alkoxyacyl-3-(3,5-dihalogenophenyl)hydantoin derivatives, their preparation and bactericides for agricultural and horticultural uses containing the same as active agent
JPS5634625A (en) Antitumorigenic agent
JPS5569510A (en) Carcinostatic agent
JPS5495716A (en) Remedy for mycobacteriosis