JPS5697221A - Production of vitamin k injection preparation - Google Patents

Production of vitamin k injection preparation

Info

Publication number
JPS5697221A
JPS5697221A JP27580A JP27580A JPS5697221A JP S5697221 A JPS5697221 A JP S5697221A JP 27580 A JP27580 A JP 27580A JP 27580 A JP27580 A JP 27580A JP S5697221 A JPS5697221 A JP S5697221A
Authority
JP
Japan
Prior art keywords
vitamin
surfactant
added
preparation
injection preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP27580A
Other languages
Japanese (ja)
Inventor
Mitsuo Sakamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OTA PHARMA
OTA SEIYAKU KK
Original Assignee
OTA PHARMA
OTA SEIYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OTA PHARMA, OTA SEIYAKU KK filed Critical OTA PHARMA
Priority to JP27580A priority Critical patent/JPS5697221A/en
Publication of JPS5697221A publication Critical patent/JPS5697221A/en
Pending legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: A small amount of a specific surfactant is added to vitamin K to produce the titled preparation that is free from turbidity formation with the passage of time and has lowered side effects caused by a surfactant.
CONSTITUTION: A nonionic surfactant of less than 9 HLB such as polyoxyethylene oleyl ether (with 2 polymerization degree of ethylene oxide) is added to vitamin K such as vitamin K1 or vitamin K2 by a level of 20W30% to produce a vitamin K injection preparation. The amount of the surfactant added is lessened and the side effects are lowered, further the preparation is almost free from turbidity formation and crystallization.
COPYRIGHT: (C)1981,JPO&Japio
JP27580A 1980-01-08 1980-01-08 Production of vitamin k injection preparation Pending JPS5697221A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP27580A JPS5697221A (en) 1980-01-08 1980-01-08 Production of vitamin k injection preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27580A JPS5697221A (en) 1980-01-08 1980-01-08 Production of vitamin k injection preparation

Publications (1)

Publication Number Publication Date
JPS5697221A true JPS5697221A (en) 1981-08-05

Family

ID=11469345

Family Applications (1)

Application Number Title Priority Date Filing Date
JP27580A Pending JPS5697221A (en) 1980-01-08 1980-01-08 Production of vitamin k injection preparation

Country Status (1)

Country Link
JP (1) JPS5697221A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5867615A (en) * 1981-10-16 1983-04-22 Shiraimatsu Shinyaku Kk Stable vitamin k2 aqueous composition and its preparation
CN117064849A (en) * 2023-07-10 2023-11-17 南京臣功制药股份有限公司 Vitamin K 1 Injection and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5867615A (en) * 1981-10-16 1983-04-22 Shiraimatsu Shinyaku Kk Stable vitamin k2 aqueous composition and its preparation
CN117064849A (en) * 2023-07-10 2023-11-17 南京臣功制药股份有限公司 Vitamin K 1 Injection and preparation method thereof

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