JPS5692213A - Anticoagulant comprising n2-arylsulfonyl-l-arginine amide or its salt as active ingredient - Google Patents
Anticoagulant comprising n2-arylsulfonyl-l-arginine amide or its salt as active ingredientInfo
- Publication number
- JPS5692213A JPS5692213A JP16889579A JP16889579A JPS5692213A JP S5692213 A JPS5692213 A JP S5692213A JP 16889579 A JP16889579 A JP 16889579A JP 16889579 A JP16889579 A JP 16889579A JP S5692213 A JPS5692213 A JP S5692213A
- Authority
- JP
- Japan
- Prior art keywords
- anticoagulant
- arylsulfonyl
- salt
- active ingredient
- amide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003146 anticoagulant agent Substances 0.000 title abstract 4
- 229940127219 anticoagulant drug Drugs 0.000 title abstract 4
- 239000004480 active ingredient Substances 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 108090000190 Thrombin Proteins 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 229960004072 thrombin Drugs 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 231100000956 nontoxicity Toxicity 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 polycyclic compound Chemical group 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Landscapes
- Quinoline Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16889579A JPS5692213A (en) | 1979-12-25 | 1979-12-25 | Anticoagulant comprising n2-arylsulfonyl-l-arginine amide or its salt as active ingredient |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16889579A JPS5692213A (en) | 1979-12-25 | 1979-12-25 | Anticoagulant comprising n2-arylsulfonyl-l-arginine amide or its salt as active ingredient |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5692213A true JPS5692213A (en) | 1981-07-25 |
JPH0231055B2 JPH0231055B2 (enrdf_load_stackoverflow) | 1990-07-11 |
Family
ID=15876551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16889579A Granted JPS5692213A (en) | 1979-12-25 | 1979-12-25 | Anticoagulant comprising n2-arylsulfonyl-l-arginine amide or its salt as active ingredient |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5692213A (enrdf_load_stackoverflow) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6431727A (en) * | 1987-07-28 | 1989-02-02 | Mitsubishi Chem Ind | Dissolution of argininamide and drug composition containing argininamides |
JP2014510117A (ja) * | 2011-04-04 | 2014-04-24 | ルンドベック ファーマシューティカルズ イタリー ソシエタ ペル アチオニ | アルガトロバン一水和物合成のためのプロセス中間体の製造方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54100342A (en) * | 1977-01-19 | 1979-08-08 | Mitsubishi Chem Ind Ltd | N2-arylsulfonyl-l-alginineamide and its pharcologically acceptable salt |
-
1979
- 1979-12-25 JP JP16889579A patent/JPS5692213A/ja active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54100342A (en) * | 1977-01-19 | 1979-08-08 | Mitsubishi Chem Ind Ltd | N2-arylsulfonyl-l-alginineamide and its pharcologically acceptable salt |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6431727A (en) * | 1987-07-28 | 1989-02-02 | Mitsubishi Chem Ind | Dissolution of argininamide and drug composition containing argininamides |
JP2014510117A (ja) * | 2011-04-04 | 2014-04-24 | ルンドベック ファーマシューティカルズ イタリー ソシエタ ペル アチオニ | アルガトロバン一水和物合成のためのプロセス中間体の製造方法 |
JP2017186350A (ja) * | 2011-04-04 | 2017-10-12 | ルンドベック ファーマシューティカルズ イタリー ソシエタ ペル アチオニ | アルガトロバン一水和物合成のためのプロセス中間体の製造方法 |
US9994526B2 (en) | 2011-04-04 | 2018-06-12 | Lundbeck Pharmaceuticals Italy S.P.A. | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate |
US10385020B2 (en) | 2011-04-04 | 2019-08-20 | Lundbeck Pharmaceuticals Italy S.P.A. | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate |
Also Published As
Publication number | Publication date |
---|---|
JPH0231055B2 (enrdf_load_stackoverflow) | 1990-07-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EXPY | Cancellation because of completion of term |