JPS5685298A - Preparation of 7-aminocephem compound - Google Patents
Preparation of 7-aminocephem compoundInfo
- Publication number
- JPS5685298A JPS5685298A JP16158279A JP16158279A JPS5685298A JP S5685298 A JPS5685298 A JP S5685298A JP 16158279 A JP16158279 A JP 16158279A JP 16158279 A JP16158279 A JP 16158279A JP S5685298 A JPS5685298 A JP S5685298A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- ion exchange
- exchange resin
- immobilized enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 7-aminocephem compound Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 108700023418 Amidases Proteins 0.000 abstract 2
- 108010093096 Immobilized Enzymes Proteins 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 102000005922 amidase Human genes 0.000 abstract 2
- QITDACOZCQXYQY-BAFYGKSASA-N (6r)-7-amino-5-thia-1-azabicyclo[4.2.0]oct-2-en-8-one Chemical compound S1CC=CN2C(=O)C(N)[C@H]21 QITDACOZCQXYQY-BAFYGKSASA-N 0.000 abstract 1
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003957 anion exchange resin Substances 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229920001429 chelating resin Polymers 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003431 cross linking reagent Substances 0.000 abstract 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
- 239000006179 pH buffering agent Substances 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Landscapes
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16158279A JPS5685298A (en) | 1979-12-14 | 1979-12-14 | Preparation of 7-aminocephem compound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16158279A JPS5685298A (en) | 1979-12-14 | 1979-12-14 | Preparation of 7-aminocephem compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5685298A true JPS5685298A (en) | 1981-07-11 |
| JPS6258716B2 JPS6258716B2 (enrdf_load_stackoverflow) | 1987-12-07 |
Family
ID=15737857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP16158279A Granted JPS5685298A (en) | 1979-12-14 | 1979-12-14 | Preparation of 7-aminocephem compound |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5685298A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4981789A (en) * | 1987-03-18 | 1991-01-01 | Merck & Co., Inc. | One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives |
| US5104800A (en) * | 1989-06-27 | 1992-04-14 | Merck & Co., Inc. | One-step cephalosporin c amidase enzyme |
| EP0524604A3 (enrdf_load_stackoverflow) * | 1991-07-26 | 1994-05-04 | Lonza Ag | |
| WO2002086143A3 (en) * | 2001-04-19 | 2003-01-09 | Bioferma Murcia S A | Enzymatic process for preparing cephalosporin derivatives |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5359095A (en) * | 1976-11-05 | 1978-05-27 | Asahi Chem Ind Co Ltd | Preparation of 7-aminocephem cpds. |
| JPS53139791A (en) * | 1977-05-02 | 1978-12-06 | Asahi Chem Ind Co Ltd | Preparation of 7-aminocephem compounds |
-
1979
- 1979-12-14 JP JP16158279A patent/JPS5685298A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5359095A (en) * | 1976-11-05 | 1978-05-27 | Asahi Chem Ind Co Ltd | Preparation of 7-aminocephem cpds. |
| JPS53139791A (en) * | 1977-05-02 | 1978-12-06 | Asahi Chem Ind Co Ltd | Preparation of 7-aminocephem compounds |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4981789A (en) * | 1987-03-18 | 1991-01-01 | Merck & Co., Inc. | One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives |
| US5104800A (en) * | 1989-06-27 | 1992-04-14 | Merck & Co., Inc. | One-step cephalosporin c amidase enzyme |
| EP0524604A3 (enrdf_load_stackoverflow) * | 1991-07-26 | 1994-05-04 | Lonza Ag | |
| WO2002086143A3 (en) * | 2001-04-19 | 2003-01-09 | Bioferma Murcia S A | Enzymatic process for preparing cephalosporin derivatives |
| WO2002085914A3 (en) * | 2001-04-19 | 2003-02-06 | Bioferma Murcia S A | ENZYMATIC PROCESS FOR PREPARING CEPHALOSPORANIC ACID DERIVATIVES USING α-KETOACID DERIVATIVES |
| US6642020B2 (en) | 2001-04-19 | 2003-11-04 | Bioferma Murcia S.A. | Process for preparing cephalosporin derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6258716B2 (enrdf_load_stackoverflow) | 1987-12-07 |
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