JPS5668619A - Nifedipine-containing solid composition - Google Patents
Nifedipine-containing solid compositionInfo
- Publication number
- JPS5668619A JPS5668619A JP14220980A JP14220980A JPS5668619A JP S5668619 A JPS5668619 A JP S5668619A JP 14220980 A JP14220980 A JP 14220980A JP 14220980 A JP14220980 A JP 14220980A JP S5668619 A JPS5668619 A JP S5668619A
- Authority
- JP
- Japan
- Prior art keywords
- nifedipine
- blending
- titled composition
- base agent
- urea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 title abstract 5
- 229960001597 nifedipine Drugs 0.000 title abstract 5
- 239000008247 solid mixture Substances 0.000 title 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 238000002156 mixing Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000004202 carbamide Substances 0.000 abstract 2
- 235000013877 carbamide Nutrition 0.000 abstract 2
- 229920000609 methyl cellulose Polymers 0.000 abstract 2
- 239000001923 methylcellulose Substances 0.000 abstract 2
- 235000010981 methylcellulose Nutrition 0.000 abstract 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 2
- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 abstract 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 abstract 1
- -1 e.g. Substances 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008183 oral pharmaceutical preparation Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Landscapes
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14220980A JPS5668619A (en) | 1980-10-09 | 1980-10-09 | Nifedipine-containing solid composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14220980A JPS5668619A (en) | 1980-10-09 | 1980-10-09 | Nifedipine-containing solid composition |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6703977A Division JPS542316A (en) | 1977-06-07 | 1977-06-07 | Solid pharmaceutical composition containing nifedipene |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5668619A true JPS5668619A (en) | 1981-06-09 |
JPH037645B2 JPH037645B2 (enrdf_load_stackoverflow) | 1991-02-04 |
Family
ID=15309931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14220980A Granted JPS5668619A (en) | 1980-10-09 | 1980-10-09 | Nifedipine-containing solid composition |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5668619A (enrdf_load_stackoverflow) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2550444A1 (fr) * | 1983-08-11 | 1985-02-15 | Fujisawa Pharmaceutical Co | Preparation solide capable de liberer rapidement la dihydropyridine a, et son procede d'obtention |
JPS6092212A (ja) * | 1983-10-26 | 1985-05-23 | Kyowa Hakko Kogyo Co Ltd | ドキソルビシン塩の製剤 |
US4562069A (en) * | 1983-05-21 | 1985-12-31 | Bayer Aktiengesellschaft | Two-phase formulation |
US5854233A (en) * | 1993-09-08 | 1998-12-29 | Pharmacy And Therapeutic Advisory Consultancy Ltd. | Method of treating liver disease and like indications with vasodilating agents |
US6174917B1 (en) | 1993-09-08 | 2001-01-16 | Pharmacy And Therapeutic Advisory Consultancy Ltd. | Method of treating liver disease and like indications with vasodilating agents |
-
1980
- 1980-10-09 JP JP14220980A patent/JPS5668619A/ja active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4562069A (en) * | 1983-05-21 | 1985-12-31 | Bayer Aktiengesellschaft | Two-phase formulation |
FR2550444A1 (fr) * | 1983-08-11 | 1985-02-15 | Fujisawa Pharmaceutical Co | Preparation solide capable de liberer rapidement la dihydropyridine a, et son procede d'obtention |
JPS6038322A (ja) * | 1983-08-11 | 1985-02-27 | Fujisawa Pharmaceut Co Ltd | ジヒドロピリジンa物質含有易溶性固形製剤 |
JPS6092212A (ja) * | 1983-10-26 | 1985-05-23 | Kyowa Hakko Kogyo Co Ltd | ドキソルビシン塩の製剤 |
US5854233A (en) * | 1993-09-08 | 1998-12-29 | Pharmacy And Therapeutic Advisory Consultancy Ltd. | Method of treating liver disease and like indications with vasodilating agents |
US6174917B1 (en) | 1993-09-08 | 2001-01-16 | Pharmacy And Therapeutic Advisory Consultancy Ltd. | Method of treating liver disease and like indications with vasodilating agents |
Also Published As
Publication number | Publication date |
---|---|
JPH037645B2 (enrdf_load_stackoverflow) | 1991-02-04 |
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