JPS5651414A - Antibiotic substance neplanocin preparation - Google Patents

Antibiotic substance neplanocin preparation

Info

Publication number
JPS5651414A
JPS5651414A JP12772179A JP12772179A JPS5651414A JP S5651414 A JPS5651414 A JP S5651414A JP 12772179 A JP12772179 A JP 12772179A JP 12772179 A JP12772179 A JP 12772179A JP S5651414 A JPS5651414 A JP S5651414A
Authority
JP
Japan
Prior art keywords
neplanocin
leukemia
carcinoma
formula
antibiotic substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12772179A
Other languages
Japanese (ja)
Inventor
Kazuyoshi Nishiie
Tadayo Fujii
Masatoshi Tsujino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Priority to JP12772179A priority Critical patent/JPS5651414A/en
Publication of JPS5651414A publication Critical patent/JPS5651414A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To provide an antineoplasmic agent effective to prolong the life of the patient affected by various tumors, by the use of antibiotic substances, neplanocins, as effective components.
CONSTITUTION: An agent containing, as effective components, neplanocin A of formula I, neplanocin B of formula II and/or neplanocin C of formula III, which are novel antibiotic substances, or their pharmaceutically permissible salts. The antibiotic substances are found from the products obtained by culturing actinomyces belonging to Ampullariella genus, i.e. A11079 strain (FERM-P No.4494). The agent has remarkable life-elongation effect to the patient of L1210 tumor leukocyte, Ehrlich ascites carcinoma, sarcoma 180, P388 leukemia, and Yoshida sarcoma, and useful for the remedy of acute leukemia, chromic leukemia, carcinoma of digestive tracts, pulmonary carcinoma, uterine cancer, mammary cancer, malignant lymphoma, etc.
COPYRIGHT: (C)1981,JPO&Japio
JP12772179A 1979-10-02 1979-10-02 Antibiotic substance neplanocin preparation Pending JPS5651414A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12772179A JPS5651414A (en) 1979-10-02 1979-10-02 Antibiotic substance neplanocin preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12772179A JPS5651414A (en) 1979-10-02 1979-10-02 Antibiotic substance neplanocin preparation

Publications (1)

Publication Number Publication Date
JPS5651414A true JPS5651414A (en) 1981-05-09

Family

ID=14967061

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12772179A Pending JPS5651414A (en) 1979-10-02 1979-10-02 Antibiotic substance neplanocin preparation

Country Status (1)

Country Link
JP (1) JPS5651414A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0304889A2 (en) * 1987-08-26 1989-03-01 Merrell Pharmaceuticals Inc. Novel aristeromycin/adenosine derivatives
WO1995028940A1 (en) * 1994-04-22 1995-11-02 Department Of The Army Methods for inhibiting human immunodeficiency virus
WO2002094248A2 (en) * 2001-05-21 2002-11-28 Heinrich Wieland Composition and use of substances for stabilising amino acids containing sulphur and/or for inhibiting the continuous formation of amino acids containing sulphur in a blood sample

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0304889A2 (en) * 1987-08-26 1989-03-01 Merrell Pharmaceuticals Inc. Novel aristeromycin/adenosine derivatives
WO1995028940A1 (en) * 1994-04-22 1995-11-02 Department Of The Army Methods for inhibiting human immunodeficiency virus
WO2002094248A2 (en) * 2001-05-21 2002-11-28 Heinrich Wieland Composition and use of substances for stabilising amino acids containing sulphur and/or for inhibiting the continuous formation of amino acids containing sulphur in a blood sample
WO2002094248A3 (en) * 2001-05-21 2003-10-23 Heinrich Wieland Composition and use of substances for stabilising amino acids containing sulphur and/or for inhibiting the continuous formation of amino acids containing sulphur in a blood sample
US7306950B2 (en) 2001-05-21 2007-12-11 Heinrich Wieland Composition and use of substances for stabilising amino acids containing sulphur

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