JPS5634632A - S-sulfonated immunoglobulin composition - Google Patents
S-sulfonated immunoglobulin compositionInfo
- Publication number
- JPS5634632A JPS5634632A JP10964479A JP10964479A JPS5634632A JP S5634632 A JPS5634632 A JP S5634632A JP 10964479 A JP10964479 A JP 10964479A JP 10964479 A JP10964479 A JP 10964479A JP S5634632 A JPS5634632 A JP S5634632A
- Authority
- JP
- Japan
- Prior art keywords
- sulfonated immunoglobulin
- agglutination
- hydrochloride
- organic compound
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PURPOSE: The titled composition having suppressed agglutination and excellent stability, and useful for various infectious diseases, composed of S-sulfonated immunoglobulin and a specific organic compound salt.
CONSTITUTION: A composition composed of (A) 100pts.wt. of S-sulfonated immunoglobulin and (B) 10W600pts.wt. of a water-soluble salt of a nitrogen-containing basic organic compound having a dissociation index (pKb) of ≥7, e.g. l- arginine hydrochloride, l-lysine hydrochloride, and D-glucosamine hydrochloride. The addition of the water-soluble salt is effective to dissociate the agglutinated S- sulfonated immunoglobulin rapidly, to suppress the agglutination for a long period, and to reduce the anticomplementary value which has a relation to anaphylactic side effects accompanied with lowering of blood pressure, algor and pyrexia.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10964479A JPS5634632A (en) | 1979-08-30 | 1979-08-30 | S-sulfonated immunoglobulin composition |
CA000359215A CA1153695A (en) | 1979-08-30 | 1980-08-28 | S-sulfonated immunoglobulin composition having a high monomer content and a process for production thereof |
US06/182,053 US4360457A (en) | 1979-08-30 | 1980-08-28 | S-Sulfonated immunoglobulin composition having a high monomer content and a process for production thereof |
AT80303004T ATE6740T1 (en) | 1979-08-30 | 1980-08-29 | COMPOSITION CONTAINING AN S-SULFONATED IMMUNOGLOBULIN AND ANAGAGING PREVENTION OR AGAGING DISSOCIATION AGENT AND METHODS FOR PREPARING COMPOSITIONS CONTAINING A HIGH PROPORTION OF MONOMERIC S-SULFONATED IMMUNOGLOBULINS. |
DE8080303004T DE3067150D1 (en) | 1979-08-30 | 1980-08-29 | Composition containing s-sulfonated immunoglobulin and aggregation preventing or aggregate dissociating agent therefor, and processes for preparing compositions containing high proportions of monomeric s-sulfonated immunoglobulin |
EP80303004A EP0025321B1 (en) | 1979-08-30 | 1980-08-29 | Composition containing s-sulfonated immunoglobulin and aggregation preventing or aggregate dissociating agent therefor, and processes for preparing compositions containing high proportions of monomeric s-sulfonated immunoglobulin |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10964479A JPS5634632A (en) | 1979-08-30 | 1979-08-30 | S-sulfonated immunoglobulin composition |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5634632A true JPS5634632A (en) | 1981-04-06 |
JPS647051B2 JPS647051B2 (en) | 1989-02-07 |
Family
ID=14515500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10964479A Granted JPS5634632A (en) | 1979-08-30 | 1979-08-30 | S-sulfonated immunoglobulin composition |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5634632A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60230973A (en) * | 1984-04-05 | 1985-11-16 | メトコ・インコーポレイテツド | Thermal spray composite material and method of setting tenaceous and high temperature corrosion resistant coating |
JPS60230974A (en) * | 1984-04-05 | 1985-11-16 | メトコ・インコーポレイテツド | Thermal spray composite material and method of setting corrosion resistant coating |
JPH0375383A (en) * | 1989-08-17 | 1991-03-29 | Tocalo Co Ltd | Roll for high temperature heat treatment furnace and its production |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06278260A (en) * | 1993-03-29 | 1994-10-04 | Japan Vilene Co Ltd | Skin material for car interior, material for car interior and manufacture of them |
-
1979
- 1979-08-30 JP JP10964479A patent/JPS5634632A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60230973A (en) * | 1984-04-05 | 1985-11-16 | メトコ・インコーポレイテツド | Thermal spray composite material and method of setting tenaceous and high temperature corrosion resistant coating |
JPS60230974A (en) * | 1984-04-05 | 1985-11-16 | メトコ・インコーポレイテツド | Thermal spray composite material and method of setting corrosion resistant coating |
JPH0375383A (en) * | 1989-08-17 | 1991-03-29 | Tocalo Co Ltd | Roll for high temperature heat treatment furnace and its production |
Also Published As
Publication number | Publication date |
---|---|
JPS647051B2 (en) | 1989-02-07 |
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