JPS5629999A - Synthesis of isopenicillin derivative in absence of live cell - Google Patents

Synthesis of isopenicillin derivative in absence of live cell

Info

Publication number
JPS5629999A
JPS5629999A JP6413780A JP6413780A JPS5629999A JP S5629999 A JPS5629999 A JP S5629999A JP 6413780 A JP6413780 A JP 6413780A JP 6413780 A JP6413780 A JP 6413780A JP S5629999 A JPS5629999 A JP S5629999A
Authority
JP
Japan
Prior art keywords
isopenicillin
derivative
synthesis
absence
live cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6413780A
Other languages
English (en)
Japanese (ja)
Inventor
Eru Demein Aanorudo
Konomi Toshio
Ii Borudouin Jiyatsuku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of JPS5629999A publication Critical patent/JPS5629999A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/745—Cephalosporium ; Acremonium
    • C12R2001/75—Cephalosporium acremonium ; Acremonium strictum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/925—Cephalosporium
    • Y10S435/926—Cephalosporium acremonium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP6413780A 1979-05-17 1980-05-16 Synthesis of isopenicillin derivative in absence of live cell Pending JPS5629999A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/040,061 US4248966A (en) 1979-05-17 1979-05-17 Synthesis of isopenicillin derivatives in the absence of living cells

Publications (1)

Publication Number Publication Date
JPS5629999A true JPS5629999A (en) 1981-03-25

Family

ID=21908873

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6413780A Pending JPS5629999A (en) 1979-05-17 1980-05-16 Synthesis of isopenicillin derivative in absence of live cell

Country Status (4)

Country Link
US (1) US4248966A (OSRAM)
JP (1) JPS5629999A (OSRAM)
DE (1) DE3018767A1 (OSRAM)
GB (1) GB2052486B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012513213A (ja) * 2008-12-22 2012-06-14 グレーンライト バイオサイエンシーズ インコーポレーテッド 化合物の製造のための組成物および方法

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510246A (en) * 1982-08-23 1985-04-09 Queen's University At Kingston Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins
US4536476A (en) * 1982-08-23 1985-08-20 Queen's University At Kingston Stable epimerase reagent, cyclase reagent and ring expansion reagent for cell-free production of cephalosporins
US4693977A (en) * 1982-08-23 1987-09-15 Queen's University At Kingston Enzyme immobilization for producing cephalosporin antibiotics
US4579818A (en) * 1983-06-27 1986-04-01 Queen's University At Kingston Biosynthesis of unnatural cephalosporins
GB8519264D0 (en) * 1985-07-31 1985-09-04 Baldwin J E Chemical compounds
US4855419A (en) * 1987-06-16 1989-08-08 University Of Cincinnati Application of 4-[1-oxoalkyl]-2,5-oxazolidinediones in selective stereospecific formation of biologically active α-lactams
US5006661A (en) * 1987-06-16 1991-04-09 University Of Cincinnati Selective stereospecific biologically active beta-lactams
SK280569B6 (sk) * 1991-10-15 2000-03-13 Gist-Brocades B.V. Biologický spôsob výroby kyseliny7-aminodeacetylce
EP2376619A4 (en) 2008-12-15 2012-07-04 Greenlight Biosciences Inc METHODS FOR CONTROLLING FLOWS IN METABOLIC PATHWAYS
ES2718844T3 (es) 2010-05-07 2019-07-04 Greenlight Biosciences Inc Métodos para controlar el flujo en rutas metabólicas mediante la reubicación de enzimas
EP3219796B1 (en) 2010-08-31 2020-10-07 GreenLight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
KR20150010932A (ko) 2011-09-09 2015-01-29 그린라이트 바이오사이언시스, 아이엔씨. 카바페넴의 무세포 제조법
HK1216547A1 (zh) 2012-12-21 2016-11-18 Greenlight Biosciences Inc. 用於將甲烷轉化成燃料、丙酮酸或異丁醇的無細胞系統
KR20160037194A (ko) 2013-08-05 2016-04-05 그린라이트 바이오사이언시스, 아이엔씨. 프로테아제 분열 위치를 갖는 엔지니어링된 프로테인
AU2016243623B2 (en) 2015-03-30 2022-04-14 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
CN109196109B (zh) 2016-04-06 2024-06-25 绿光生物科技股份有限公司 无细胞生成核糖核酸
CA3078726A1 (en) 2017-10-11 2019-04-18 Greenlight Biosciences, Inc. Methods and compositions for nucleoside triphosphate and ribonucleic acid production

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002530A (en) * 1974-03-07 1977-01-11 Recherche Et Industrie Therapeutiques (R.I.T.) 6-Aminopenicillanic acid derivative

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012513213A (ja) * 2008-12-22 2012-06-14 グレーンライト バイオサイエンシーズ インコーポレーテッド 化合物の製造のための組成物および方法

Also Published As

Publication number Publication date
GB2052486A (en) 1981-01-28
GB2052486B (en) 1983-04-20
US4248966A (en) 1981-02-03
DE3018767C2 (OSRAM) 1988-11-24
DE3018767A1 (de) 1980-11-27

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