JPS5624664B2 - - Google Patents

Info

Publication number
JPS5624664B2
JPS5624664B2 JP7340573A JP7340573A JPS5624664B2 JP S5624664 B2 JPS5624664 B2 JP S5624664B2 JP 7340573 A JP7340573 A JP 7340573A JP 7340573 A JP7340573 A JP 7340573A JP S5624664 B2 JPS5624664 B2 JP S5624664B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP7340573A
Other languages
Japanese (ja)
Other versions
JPS5024216A (show.php
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP7340573A priority Critical patent/JPS5624664B2/ja
Priority to IT2444874A priority patent/IT1015418B/it
Priority to DE19742430998 priority patent/DE2430998A1/de
Priority to NL7408784A priority patent/NL7408784A/xx
Priority to FR7422691A priority patent/FR2235112A1/fr
Publication of JPS5024216A publication Critical patent/JPS5024216A/ja
Publication of JPS5624664B2 publication Critical patent/JPS5624664B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/16Nitrogen-containing compounds
    • C08K5/20Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyethers (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Paper (AREA)
JP7340573A 1973-06-28 1973-06-28 Expired JPS5624664B2 (show.php)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP7340573A JPS5624664B2 (show.php) 1973-06-28 1973-06-28
IT2444874A IT1015418B (it) 1973-06-28 1974-06-25 Composti organici e procedimento per la loro preparazione
DE19742430998 DE2430998A1 (de) 1973-06-28 1974-06-27 Neue organische verbindungen mit einer n,n-dialkylsubstibuierten amidgruppe und verfahren zu deren herstellung
NL7408784A NL7408784A (show.php) 1973-06-28 1974-06-28
FR7422691A FR2235112A1 (en) 1973-06-28 1974-06-28 Cpds contg dialkyl-substd amide gps - used as surfactants, dispersants, solvents, chelating agents and polymer modifiers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7340573A JPS5624664B2 (show.php) 1973-06-28 1973-06-28

Publications (2)

Publication Number Publication Date
JPS5024216A JPS5024216A (show.php) 1975-03-15
JPS5624664B2 true JPS5624664B2 (show.php) 1981-06-08

Family

ID=13517239

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7340573A Expired JPS5624664B2 (show.php) 1973-06-28 1973-06-28

Country Status (5)

Country Link
JP (1) JPS5624664B2 (show.php)
DE (1) DE2430998A1 (show.php)
FR (1) FR2235112A1 (show.php)
IT (1) IT1015418B (show.php)
NL (1) NL7408784A (show.php)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5524563A (en) * 1978-08-09 1980-02-21 Nitto Electric Ind Co Ltd Tubular membrane separating module
EP1912679A4 (en) * 2005-06-15 2009-07-29 Massachusetts Inst Technology AMINOUS LIPIDS AND ITS USES
CN102245559B (zh) 2008-11-07 2015-05-27 麻省理工学院 氨基醇类脂质和其用途
EP3403647A1 (en) 2009-12-01 2018-11-21 Translate Bio, Inc. Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
EP2691443B1 (en) 2011-03-28 2021-02-17 Massachusetts Institute of Technology Conjugated lipomers and uses thereof
ES2740248T3 (es) 2011-06-08 2020-02-05 Translate Bio Inc Composiciones de nanopartículas lipídicas y métodos para la administración ARNm
US20150267192A1 (en) 2012-06-08 2015-09-24 Shire Human Genetic Therapies, Inc. Nuclease resistant polynucleotides and uses thereof
WO2014028487A1 (en) 2012-08-13 2014-02-20 Massachusetts Institute Of Technology Amine-containing lipidoids and uses thereof
ES2708561T3 (es) 2013-03-14 2019-04-10 Translate Bio Inc Métodos para la purificación de ARN mensajero
SI2968586T1 (sl) 2013-03-14 2018-12-31 Translate Bio, Inc. Sestavki CFTR MRNA in z njimi povezani postopki in uporabe
WO2014179562A1 (en) 2013-05-01 2014-11-06 Massachusetts Institute Of Technology 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof
SG11201602943PA (en) 2013-10-22 2016-05-30 Shire Human Genetic Therapies Lipid formulations for delivery of messenger rna
MX2016005239A (es) 2013-10-22 2016-08-12 Shire Human Genetic Therapies Tratamiento con acido ribonucleico mensajero para la fenilcetonuria.
EP3501605B1 (en) 2013-10-22 2023-06-28 Translate Bio, Inc. Mrna therapy for argininosuccinate synthetase deficiency
BR112016024632A2 (pt) 2014-04-25 2018-01-30 Shire Human Genetic Therapies métodos de purificação de rna mensageiro
JP6557722B2 (ja) 2014-05-30 2019-08-07 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド 核酸の送達のための生分解性脂質
EP3160959B1 (en) 2014-06-24 2023-08-30 Translate Bio, Inc. Stereochemically enriched compositions for delivery of nucleic acids
US9840479B2 (en) 2014-07-02 2017-12-12 Massachusetts Institute Of Technology Polyamine-fatty acid derived lipidoids and uses thereof
EA201991747A1 (ru) 2017-02-27 2020-06-04 Транслейт Био, Инк. НОВАЯ КОДОН-ОПТИМИЗИРОВАННАЯ мРНК CFTR
US11173190B2 (en) 2017-05-16 2021-11-16 Translate Bio, Inc. Treatment of cystic fibrosis by delivery of codon-optimized mRNA encoding CFTR
CN112930396B (zh) 2018-08-24 2024-05-24 川斯勒佰尔公司 用于纯化信使rna的方法
CA3120647A1 (en) 2018-11-21 2020-05-28 Translate Bio, Inc. Treatment of cystic fibrosis by delivery of nebulized mrna encoding cftr

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2372808A (en) * 1941-07-30 1945-04-03 Resinous Prod & Chemical Co Esters of poly-beta-carboxyalkyl ethers of polyhydric alcohols

Also Published As

Publication number Publication date
JPS5024216A (show.php) 1975-03-15
IT1015418B (it) 1977-05-10
DE2430998A1 (de) 1975-01-09
NL7408784A (show.php) 1974-12-31
FR2235112A1 (en) 1975-01-24

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