JPS56164152A - Novel desacylpepsidin derivative and its preparation - Google Patents
Novel desacylpepsidin derivative and its preparationInfo
- Publication number
- JPS56164152A JPS56164152A JP6597380A JP6597380A JPS56164152A JP S56164152 A JPS56164152 A JP S56164152A JP 6597380 A JP6597380 A JP 6597380A JP 6597380 A JP6597380 A JP 6597380A JP S56164152 A JPS56164152 A JP S56164152A
- Authority
- JP
- Japan
- Prior art keywords
- desacylpepsidin
- derivative
- formula
- novel
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
NEW MATERIAL:A desacylpepsidin derivative of formula I (R is carboxypropanoyl, 2-carboxybenzoyl or nicotinoyl).
EXAMPLE: N-3-Carboxypropanoyl-desacylpepsidin.
USE: Useful for the prevention and remedy of various diseases due to hypersecretion of pepsin, e.g. peptic ulcer or hypertension, having a powerful antipepsin, inhibitory action on acidic protease and antirenin action, and very stable under physiological conditions.
PROCESS: Desacylpepsidin of formula II is reacted with an organic carboxylic acid, e.g. succinc or phthalic acid, or a reactive derivative thereof, e.g. acid anhydride, to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6597380A JPS56164152A (en) | 1980-05-20 | 1980-05-20 | Novel desacylpepsidin derivative and its preparation |
DE8181103882T DE3160647D1 (en) | 1980-05-20 | 1981-05-20 | Peptide derivatives and process for the preparation thereof |
EP19810103882 EP0040435B1 (en) | 1980-05-20 | 1981-05-20 | Peptide derivatives and process for the preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6597380A JPS56164152A (en) | 1980-05-20 | 1980-05-20 | Novel desacylpepsidin derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56164152A true JPS56164152A (en) | 1981-12-17 |
Family
ID=13302444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6597380A Pending JPS56164152A (en) | 1980-05-20 | 1980-05-20 | Novel desacylpepsidin derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56164152A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5167791A (en) * | 1974-12-05 | 1976-06-11 | Eisai Co Ltd | Desuashiruu oyobi desuashirubariruupepushijinno seizoho narabini saiashirukaho |
-
1980
- 1980-05-20 JP JP6597380A patent/JPS56164152A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5167791A (en) * | 1974-12-05 | 1976-06-11 | Eisai Co Ltd | Desuashiruu oyobi desuashirubariruupepushijinno seizoho narabini saiashirukaho |
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