JPS56156282A - Beta-lactam compound and its preparation - Google Patents
Beta-lactam compound and its preparationInfo
- Publication number
- JPS56156282A JPS56156282A JP6038280A JP6038280A JPS56156282A JP S56156282 A JPS56156282 A JP S56156282A JP 6038280 A JP6038280 A JP 6038280A JP 6038280 A JP6038280 A JP 6038280A JP S56156282 A JPS56156282 A JP S56156282A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- preparation
- compound
- remedy
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:Compounds of formula I (R is H, -SO3H) and their salts.
EXAMPLE: [5R,6R]-6-[1-Hydroxy-1-methylethyl]-7-oxo-1-azabicyclo[3,2,0]hept-2- ene-2-carboxylic sodium salt.
USE: Remedy for microbisms such as coil infections: they show antibacterial activity against gram-positive and -negative bacteria. They also are used as a bactericide or desinfectant for animal's hands, legs, eyes, ears, etc. Further, they show an activity of inhibiting β-lactamase and are used as a remedy for infections caused by bacteria resisting β-lactam antibiotics.
PREPARATION: The reductive cleavage of a compound of formula II (n is 0, 1) or its salt is conducted in the presence of a platinum catalyst in water or a polar organic solvent such as a combination of water and dioxane at 0W50°C under a hydrogen partial pressure of 1W2 atmospheric one to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6038280A JPS56156282A (en) | 1980-05-06 | 1980-05-06 | Beta-lactam compound and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6038280A JPS56156282A (en) | 1980-05-06 | 1980-05-06 | Beta-lactam compound and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56156282A true JPS56156282A (en) | 1981-12-02 |
Family
ID=13140534
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6038280A Pending JPS56156282A (en) | 1980-05-06 | 1980-05-06 | Beta-lactam compound and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56156282A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4640915A (en) * | 1982-03-29 | 1987-02-03 | Fujisawa Pharmaceutical Co., Ltd. | 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives |
-
1980
- 1980-05-06 JP JP6038280A patent/JPS56156282A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4640915A (en) * | 1982-03-29 | 1987-02-03 | Fujisawa Pharmaceutical Co., Ltd. | 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives |
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