JPS56156282A - Beta-lactam compound and its preparation - Google Patents

Beta-lactam compound and its preparation

Info

Publication number
JPS56156282A
JPS56156282A JP6038280A JP6038280A JPS56156282A JP S56156282 A JPS56156282 A JP S56156282A JP 6038280 A JP6038280 A JP 6038280A JP 6038280 A JP6038280 A JP 6038280A JP S56156282 A JPS56156282 A JP S56156282A
Authority
JP
Japan
Prior art keywords
formula
preparation
compound
remedy
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6038280A
Other languages
Japanese (ja)
Inventor
Mitsuko Asai
Susumu Shinagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP6038280A priority Critical patent/JPS56156282A/en
Publication of JPS56156282A publication Critical patent/JPS56156282A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:Compounds of formula I (R is H, -SO3H) and their salts.
EXAMPLE: [5R,6R]-6-[1-Hydroxy-1-methylethyl]-7-oxo-1-azabicyclo[3,2,0]hept-2- ene-2-carboxylic sodium salt.
USE: Remedy for microbisms such as coil infections: they show antibacterial activity against gram-positive and -negative bacteria. They also are used as a bactericide or desinfectant for animal's hands, legs, eyes, ears, etc. Further, they show an activity of inhibiting β-lactamase and are used as a remedy for infections caused by bacteria resisting β-lactam antibiotics.
PREPARATION: The reductive cleavage of a compound of formula II (n is 0, 1) or its salt is conducted in the presence of a platinum catalyst in water or a polar organic solvent such as a combination of water and dioxane at 0W50°C under a hydrogen partial pressure of 1W2 atmospheric one to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP6038280A 1980-05-06 1980-05-06 Beta-lactam compound and its preparation Pending JPS56156282A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6038280A JPS56156282A (en) 1980-05-06 1980-05-06 Beta-lactam compound and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6038280A JPS56156282A (en) 1980-05-06 1980-05-06 Beta-lactam compound and its preparation

Publications (1)

Publication Number Publication Date
JPS56156282A true JPS56156282A (en) 1981-12-02

Family

ID=13140534

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6038280A Pending JPS56156282A (en) 1980-05-06 1980-05-06 Beta-lactam compound and its preparation

Country Status (1)

Country Link
JP (1) JPS56156282A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4640915A (en) * 1982-03-29 1987-02-03 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4640915A (en) * 1982-03-29 1987-02-03 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives

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