JPS5788182A - Pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acid derivative - Google Patents
Pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acid derivativeInfo
- Publication number
- JPS5788182A JPS5788182A JP55164176A JP16417680A JPS5788182A JP S5788182 A JPS5788182 A JP S5788182A JP 55164176 A JP55164176 A JP 55164176A JP 16417680 A JP16417680 A JP 16417680A JP S5788182 A JPS5788182 A JP S5788182A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pyrido
- formula
- benzoxazinecarboxylic
- acid derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The compound of formulaI(R is H or lower alkyl; Y is cyclic substituted amino having double bond) or its salt.
EXAMPLE: 9-Fluoro-3-methyl-7-oxo-10-(3-pyrrolin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3- de][1,4]-benzoxazine-6-carboxylic acid.
USE: Antibacterial agent having strong antibacterial activity against Gram-negative and Gram-positive bacteria including Pseudomonas aeruginosa.
PROCESS: The compound of formulaIis prepared by heating the compound of formula II together with the amine of formula Y'H (Y' is Y or its dihydroxy compound) without solvent or in polar solvent such as dimethyl sulfoxide at room temp. W200°C.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55164176A JPS5788182A (en) | 1980-11-21 | 1980-11-21 | Pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55164176A JPS5788182A (en) | 1980-11-21 | 1980-11-21 | Pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5788182A true JPS5788182A (en) | 1982-06-01 |
Family
ID=15788160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55164176A Pending JPS5788182A (en) | 1980-11-21 | 1980-11-21 | Pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5788182A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4472406A (en) * | 1982-11-12 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo [ij]quinolizine-2-carboxylic acids and derivatives |
US4530930A (en) * | 1982-12-29 | 1985-07-23 | Kanebo, Ltd. | Antimicrobial 1-ethyl-6,8-difluoro-1,4-dihydro-7-(1-imidazolyl)-4-oxoquinoline-3-carboxylic acid derivatives |
US4567269A (en) * | 1982-11-12 | 1986-01-28 | Riker Laboratories, Inc. | Intermediates for the preparation of 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acids |
JPS62145088A (en) * | 1985-12-10 | 1987-06-29 | バイエル・アクチエンゲゼルシヤフト | Enantiomerically pure 1, 8-crosslinked 4-quinolone-3- carboxylic acid |
US6689769B2 (en) | 2000-12-21 | 2004-02-10 | Pharmacia & Upjohn Company | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6111955A (en) * | 1984-06-27 | 1986-01-20 | Matsushita Electric Ind Co Ltd | Magnetic recording and reproducing device |
-
1980
- 1980-11-21 JP JP55164176A patent/JPS5788182A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6111955A (en) * | 1984-06-27 | 1986-01-20 | Matsushita Electric Ind Co Ltd | Magnetic recording and reproducing device |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4472406A (en) * | 1982-11-12 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo [ij]quinolizine-2-carboxylic acids and derivatives |
US4567269A (en) * | 1982-11-12 | 1986-01-28 | Riker Laboratories, Inc. | Intermediates for the preparation of 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acids |
US4530930A (en) * | 1982-12-29 | 1985-07-23 | Kanebo, Ltd. | Antimicrobial 1-ethyl-6,8-difluoro-1,4-dihydro-7-(1-imidazolyl)-4-oxoquinoline-3-carboxylic acid derivatives |
JPS62145088A (en) * | 1985-12-10 | 1987-06-29 | バイエル・アクチエンゲゼルシヤフト | Enantiomerically pure 1, 8-crosslinked 4-quinolone-3- carboxylic acid |
US6689769B2 (en) | 2000-12-21 | 2004-02-10 | Pharmacia & Upjohn Company | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
US6869965B2 (en) | 2000-12-21 | 2005-03-22 | Pharmacia & Upjohn Company | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
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