JPS5711982A - Novel antibiotic and its preparation - Google Patents

Novel antibiotic and its preparation

Info

Publication number
JPS5711982A
JPS5711982A JP8698980A JP8698980A JPS5711982A JP S5711982 A JPS5711982 A JP S5711982A JP 8698980 A JP8698980 A JP 8698980A JP 8698980 A JP8698980 A JP 8698980A JP S5711982 A JPS5711982 A JP S5711982A
Authority
JP
Japan
Prior art keywords
formula
mercuric
preparation
salt
compound shown
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8698980A
Other languages
Japanese (ja)
Inventor
Masato Nakayama
Shigeru Kimura
Toshimi Mizoguchi
Sohei Tanabe
Toshito Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Priority to JP8698980A priority Critical patent/JPS5711982A/en
Publication of JPS5711982A publication Critical patent/JPS5711982A/en
Pending legal-status Critical Current

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  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:An antibiotic shown by the formula I (R is H or sulfonic acid group) and its salt.
EXAMPLE: Sodium (5R, 6R)-3-[ (Z)-2-acetamidoethenylsulfinyl ]-6-(2-hydroxy-2- propyl)-7-oxo-1-azabicyclo[3,2,0]hepto-2-ene-carboxylate.
USE: Having improved antibacterial activity, and stable to enzymes in a living body.
PROCESS: For example, an (E) compound shown by the formula II is reacted with a mercuric salt, e.g., mercuric chloride, mercuric bromide, etc. in an inert solvent, e.g., acetonitrile, etc., to give a compound shown by the formula I.
COPYRIGHT: (C)1982,JPO&Japio
JP8698980A 1980-06-26 1980-06-26 Novel antibiotic and its preparation Pending JPS5711982A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8698980A JPS5711982A (en) 1980-06-26 1980-06-26 Novel antibiotic and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8698980A JPS5711982A (en) 1980-06-26 1980-06-26 Novel antibiotic and its preparation

Publications (1)

Publication Number Publication Date
JPS5711982A true JPS5711982A (en) 1982-01-21

Family

ID=13902268

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8698980A Pending JPS5711982A (en) 1980-06-26 1980-06-26 Novel antibiotic and its preparation

Country Status (1)

Country Link
JP (1) JPS5711982A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983002614A1 (en) * 1982-02-02 1983-08-04 Takeda Chemical Industries Ltd 5,6-cis-carbapenem-3-carboxylic acid derivatives and process for their preparation
US4497742A (en) * 1981-03-04 1985-02-05 Takeda Chemical Industries, Ltd. Isomerization of β-lactam compounds

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4497742A (en) * 1981-03-04 1985-02-05 Takeda Chemical Industries, Ltd. Isomerization of β-lactam compounds
WO1983002614A1 (en) * 1982-02-02 1983-08-04 Takeda Chemical Industries Ltd 5,6-cis-carbapenem-3-carboxylic acid derivatives and process for their preparation

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