JPS56150051A - Manufacture of insulin precursor - Google Patents
Manufacture of insulin precursorInfo
- Publication number
- JPS56150051A JPS56150051A JP4612381A JP4612381A JPS56150051A JP S56150051 A JPS56150051 A JP S56150051A JP 4612381 A JP4612381 A JP 4612381A JP 4612381 A JP4612381 A JP 4612381A JP S56150051 A JPS56150051 A JP S56150051A
- Authority
- JP
- Japan
- Prior art keywords
- manufacture
- insulin precursor
- insulin
- precursor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
- 102000004877 Insulin Human genes 0.000 title 1
- 108090001061 Insulin Proteins 0.000 title 1
- 229940125396 insulin Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002243 precursor Substances 0.000 title 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13438980A | 1980-03-27 | 1980-03-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56150051A true JPS56150051A (en) | 1981-11-20 |
| JPH0148278B2 JPH0148278B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1989-10-18 |
Family
ID=22463150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4612381A Granted JPS56150051A (en) | 1980-03-27 | 1981-03-27 | Manufacture of insulin precursor |
Country Status (3)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58190398A (ja) * | 1982-03-13 | 1983-11-07 | ヘキスト・アクチエンゲゼルシヤフト | インシユリンへのプレプロインシユリン類似体の変換法 |
| JPS61221200A (ja) * | 1985-03-22 | 1986-10-01 | ノボ ノルディスク アクティーゼルスカブ | インシュリンの製造方法 |
| JPS62501501A (ja) * | 1985-01-19 | 1987-06-18 | ヘキスト・アクチエンゲゼルシヤフト | 相当するｓ−スルホネ−トからインシユリン前駆体の折りたたみに際し得られる反応混合物からのインシユリン前駆体の取得法 |
| JP2003511018A (ja) * | 1999-10-02 | 2003-03-25 | アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | インスリンおよびインスリン類似体の製造を改善するｃペプチド |
-
1981
- 1981-03-24 ZA ZA00811972A patent/ZA811972B/xx unknown
- 1981-03-24 PH PH25410A patent/PH16156A/en unknown
- 1981-03-27 JP JP4612381A patent/JPS56150051A/ja active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58190398A (ja) * | 1982-03-13 | 1983-11-07 | ヘキスト・アクチエンゲゼルシヤフト | インシユリンへのプレプロインシユリン類似体の変換法 |
| JPS62501501A (ja) * | 1985-01-19 | 1987-06-18 | ヘキスト・アクチエンゲゼルシヤフト | 相当するｓ−スルホネ−トからインシユリン前駆体の折りたたみに際し得られる反応混合物からのインシユリン前駆体の取得法 |
| JPS61221200A (ja) * | 1985-03-22 | 1986-10-01 | ノボ ノルディスク アクティーゼルスカブ | インシュリンの製造方法 |
| JP2003511018A (ja) * | 1999-10-02 | 2003-03-25 | アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | インスリンおよびインスリン類似体の製造を改善するｃペプチド |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA811972B (en) | 1982-11-24 |
| JPH0148278B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1989-10-18 |
| PH16156A (en) | 1983-07-18 |
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