JPS56139500A - Salt of dc-11 - Google Patents

Salt of dc-11

Info

Publication number
JPS56139500A
JPS56139500A JP4293680A JP4293680A JPS56139500A JP S56139500 A JPS56139500 A JP S56139500A JP 4293680 A JP4293680 A JP 4293680A JP 4293680 A JP4293680 A JP 4293680A JP S56139500 A JPS56139500 A JP S56139500A
Authority
JP
Japan
Prior art keywords
salt
base
solution
dried
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4293680A
Other languages
Japanese (ja)
Inventor
Masaji Kasai
Kimikatsu Shirahata
Fusao Tomita
Tatsuya Tamaoki
Makoto Morimoto
Masanori Fukui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP4293680A priority Critical patent/JPS56139500A/en
Publication of JPS56139500A publication Critical patent/JPS56139500A/en
Pending legal-status Critical Current

Links

Landscapes

  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

NEW MATERIAL:An alkali or alkaline earth metal salt of an antibiotic substance, DC-11.
USE: Antibacterial agent and antitumor agent.
PROCESS: DC-11 is dissolved in a hydrophilic solvent such as acetone, and neutralized with an aqueous solution of a base such as NaHCO3, Na2CO3, etc. The solvent is removed from the solution under reduced pressure, and the remaining aqueous solution is freeze-dried or dried after vacuum concentration to obtain a salt of DC-11 As an alternative method, the solution of DC-11 in the hydrophilic solvent is mixed with excessive base, dried by the above-mentioned methods, mixed with an organic solvent (e.g. ethyl acetate) which does not dissolve the base and dissolves the DC-11 salt, and filtered to remove the excessive base from the solution of the DC-11 salt.
COPYRIGHT: (C)1981,JPO&Japio
JP4293680A 1980-04-02 1980-04-02 Salt of dc-11 Pending JPS56139500A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4293680A JPS56139500A (en) 1980-04-02 1980-04-02 Salt of dc-11

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4293680A JPS56139500A (en) 1980-04-02 1980-04-02 Salt of dc-11

Publications (1)

Publication Number Publication Date
JPS56139500A true JPS56139500A (en) 1981-10-30

Family

ID=12649893

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4293680A Pending JPS56139500A (en) 1980-04-02 1980-04-02 Salt of dc-11

Country Status (1)

Country Link
JP (1) JPS56139500A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548536B2 (en) 1998-08-31 2003-04-15 Kyowa Hakko Kogyo Co., Ltd. Agent for inducing apoptosis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54138501A (en) * 1978-04-20 1979-10-27 Kyowa Hakko Kogyo Co Ltd Antibiotic dc-11 and preparation thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54138501A (en) * 1978-04-20 1979-10-27 Kyowa Hakko Kogyo Co Ltd Antibiotic dc-11 and preparation thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548536B2 (en) 1998-08-31 2003-04-15 Kyowa Hakko Kogyo Co., Ltd. Agent for inducing apoptosis

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