JPS56139500A - Salt of dc-11 - Google Patents
Salt of dc-11Info
- Publication number
- JPS56139500A JPS56139500A JP4293680A JP4293680A JPS56139500A JP S56139500 A JPS56139500 A JP S56139500A JP 4293680 A JP4293680 A JP 4293680A JP 4293680 A JP4293680 A JP 4293680A JP S56139500 A JPS56139500 A JP S56139500A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- base
- solution
- dried
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
NEW MATERIAL:An alkali or alkaline earth metal salt of an antibiotic substance, DC-11.
USE: Antibacterial agent and antitumor agent.
PROCESS: DC-11 is dissolved in a hydrophilic solvent such as acetone, and neutralized with an aqueous solution of a base such as NaHCO3, Na2CO3, etc. The solvent is removed from the solution under reduced pressure, and the remaining aqueous solution is freeze-dried or dried after vacuum concentration to obtain a salt of DC-11 As an alternative method, the solution of DC-11 in the hydrophilic solvent is mixed with excessive base, dried by the above-mentioned methods, mixed with an organic solvent (e.g. ethyl acetate) which does not dissolve the base and dissolves the DC-11 salt, and filtered to remove the excessive base from the solution of the DC-11 salt.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4293680A JPS56139500A (en) | 1980-04-02 | 1980-04-02 | Salt of dc-11 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4293680A JPS56139500A (en) | 1980-04-02 | 1980-04-02 | Salt of dc-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56139500A true JPS56139500A (en) | 1981-10-30 |
Family
ID=12649893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4293680A Pending JPS56139500A (en) | 1980-04-02 | 1980-04-02 | Salt of dc-11 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56139500A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6548536B2 (en) | 1998-08-31 | 2003-04-15 | Kyowa Hakko Kogyo Co., Ltd. | Agent for inducing apoptosis |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54138501A (en) * | 1978-04-20 | 1979-10-27 | Kyowa Hakko Kogyo Co Ltd | Antibiotic dc-11 and preparation thereof |
-
1980
- 1980-04-02 JP JP4293680A patent/JPS56139500A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54138501A (en) * | 1978-04-20 | 1979-10-27 | Kyowa Hakko Kogyo Co Ltd | Antibiotic dc-11 and preparation thereof |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6548536B2 (en) | 1998-08-31 | 2003-04-15 | Kyowa Hakko Kogyo Co., Ltd. | Agent for inducing apoptosis |
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