JPS56139488A - Sesquiterpene compound and its preparation - Google Patents
Sesquiterpene compound and its preparationInfo
- Publication number
- JPS56139488A JPS56139488A JP4258180A JP4258180A JPS56139488A JP S56139488 A JPS56139488 A JP S56139488A JP 4258180 A JP4258180 A JP 4258180A JP 4258180 A JP4258180 A JP 4258180A JP S56139488 A JPS56139488 A JP S56139488A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- methanol
- give
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A sesquiterpene compound shown by the formula IV.
USE: A synthetic intermediate for an antitumor agent.
PROCESS: A compound shown by the formula III is heated under refulx and acidic conditions, to give a compound shown by the formula IV. The reaction is preferably carried out in dilute hydrochloric acid- methanol or dilute sulfuric acid -methanol, the reaction temperature is 50W100°C, and the reaction time is about 5W30min. The prepared compound shown by the formula IV, for example, is converted to 10α- vinyl derivative shown by the formula V, which is reacted with phenylselenyl chloride in the presence of a strong base and treated with an oxidizing agent, to give 8-deoxybernolepin shown by the formula IV, an antitumor agent.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4258180A JPS56139488A (en) | 1980-04-01 | 1980-04-01 | Sesquiterpene compound and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4258180A JPS56139488A (en) | 1980-04-01 | 1980-04-01 | Sesquiterpene compound and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56139488A true JPS56139488A (en) | 1981-10-30 |
JPS5719115B2 JPS5719115B2 (en) | 1982-04-20 |
Family
ID=12640029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4258180A Granted JPS56139488A (en) | 1980-04-01 | 1980-04-01 | Sesquiterpene compound and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56139488A (en) |
-
1980
- 1980-04-01 JP JP4258180A patent/JPS56139488A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS5719115B2 (en) | 1982-04-20 |
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