JPS56139417A - Ophthalmic composition of carbonic anhydrase inhibitor for local application to high intraocular pressure treatment - Google Patents

Ophthalmic composition of carbonic anhydrase inhibitor for local application to high intraocular pressure treatment

Info

Publication number
JPS56139417A
JPS56139417A JP3003081A JP3003081A JPS56139417A JP S56139417 A JPS56139417 A JP S56139417A JP 3003081 A JP3003081 A JP 3003081A JP 3003081 A JP3003081 A JP 3003081A JP S56139417 A JPS56139417 A JP S56139417A
Authority
JP
Japan
Prior art keywords
carbonic anhydrase
intraocular pressure
pressure treatment
local application
dibasic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3003081A
Other languages
English (en)
Japanese (ja)
Inventor
Eru Sumisu Robaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS56139417A publication Critical patent/JPS56139417A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP3003081A 1980-03-04 1981-03-04 Ophthalmic composition of carbonic anhydrase inhibitor for local application to high intraocular pressure treatment Pending JPS56139417A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12843980A 1980-03-04 1980-03-04

Publications (1)

Publication Number Publication Date
JPS56139417A true JPS56139417A (en) 1981-10-30

Family

ID=22435394

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3003081A Pending JPS56139417A (en) 1980-03-04 1981-03-04 Ophthalmic composition of carbonic anhydrase inhibitor for local application to high intraocular pressure treatment

Country Status (8)

Country Link
EP (1) EP0036351B1 (enExample)
JP (1) JPS56139417A (enExample)
AT (1) ATE11011T1 (enExample)
DE (1) DE3167999D1 (enExample)
DK (1) DK94781A (enExample)
GR (1) GR74437B (enExample)
IE (1) IE50901B1 (enExample)
PT (1) PT72600B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2155331B (en) * 1980-07-09 1988-09-01 Florida University Of Composition for reducing intraocular pressure
US4975449A (en) * 1983-02-04 1990-12-04 University Of Iowa Research Foundation Topical treatment of glaucoma with 2-benzothiazolesulfonamide derivative
US4483872A (en) * 1983-02-04 1984-11-20 University Of Iowa Research Foundation Non-classical topical treatment for glaucoma using n-substituted sulfonamides
US5095026A (en) * 1983-02-04 1992-03-10 University Of Iowa Research Foundation Prodrugs of carbonic anhydrase inhibitors
US4483864A (en) * 1983-02-04 1984-11-20 University Of Iowa Research Foundation Non-classical topical treatment for glaucoma
US4542152A (en) * 1983-05-23 1985-09-17 Merck & Co., Inc. 5-[Phenylsulfonyl(or sulfinyl)]thiophene-2-sulfonamides for the topical treatment of elevated intraocular pressure
US4585787A (en) * 1983-06-20 1986-04-29 Merck & Co., Inc. 5-[2(Or 3)-hydroxyphenylsulfonyl]thiophene-2-sulfonamides for the topical treatment of elevated intraocular pressure
DE3502962A1 (de) * 1985-01-30 1986-07-31 Merck Patent Gmbh, 6100 Darmstadt Komprimat
US5182264A (en) * 1986-03-07 1993-01-26 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
CA1311686C (en) * 1986-06-25 1992-12-22 John Weldon Shell Controlled release bioerodible drug delivery system
DE3700379A1 (de) * 1987-01-08 1988-07-21 Mann Gerhard Chem Pharm Fab Konservierte augentropfen mit einem gehalt an cromoglicinsaeure
GB2203039B (en) * 1987-03-02 1990-10-24 American Cyanamid Co Stable ophthalmic preparations containing acetazolamide
SG84487A1 (en) * 1991-04-17 2001-11-20 Merck & Co Inc Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a b-adrenergic antagonist
CA2294343A1 (en) * 1997-06-26 1999-01-07 Merck & Co., Inc. Method for optimizing retinal and optic nerve health
TWI290470B (en) * 1999-12-01 2007-12-01 Sankyo Co The composition for treating glaucoma

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB860371A (en) * 1958-07-03 1961-02-01 Pfizer & Co C Di-sulfonamides and compositions containing them
GB851287A (en) * 1958-07-10 1960-10-12 British Drug Houses Ltd 5-chlorotoluene-2:4-disulphonamide and alkali metal salts thereof
NL7508856A (nl) * 1974-08-16 1976-02-18 Merck & Co Inc Werkwijze voor het bereiden van preparaten tegen hypertensie.
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4008719A (en) * 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
NZ192673A (en) * 1979-02-02 1984-07-06 Merck & Co Inc Ophthalmic compositions for lowering intraocular pressure
EP0033042B1 (en) * 1980-01-28 1984-08-22 Merck & Co. Inc. Ophthalmic inserts for lowering intraocular pressure comprising carbonic anhydrase inhibitors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEM ABSTR89 *
CHEM ABSTR91 *

Also Published As

Publication number Publication date
DK94781A (da) 1981-09-05
PT72600B (en) 1982-12-20
EP0036351A2 (en) 1981-09-23
IE810429L (en) 1981-09-04
PT72600A (en) 1981-04-01
DE3167999D1 (en) 1985-02-14
EP0036351B1 (en) 1985-01-02
ATE11011T1 (de) 1985-01-15
EP0036351A3 (en) 1981-11-04
IE50901B1 (en) 1986-08-06
GR74437B (enExample) 1984-06-28

Similar Documents

Publication Publication Date Title
ATE9059T1 (de) Ophthalmische kohlensaure anhydrase-inhibitoren enthaltende einlagen zur verringerung intraokularer hypertension.
JPS56139417A (en) Ophthalmic composition of carbonic anhydrase inhibitor for local application to high intraocular pressure treatment
ES352625A1 (es) Procedimiento para la preparacion de una cefalosporina 3,7-disustituida.
ES449162A1 (es) Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.
ATE191143T1 (de) Verwendung von nichtsteroidalen cyclooxygenasehemmern zur herstellung eines medikaments zur behandlung vom erhoehten augeninnendruck
IE41374B1 (en) A composition for treating schizophrenia
ES8801310A1 (es) Un procedimiento para preparar derivados de alanil-protina.
FR2430939B1 (enExample)
ATE78031T1 (de) Prostaglandin-derivate zur behandlung von glaucoma oder augenueberdruck.
ATE57095T1 (de) Verwendung von hydroxyindolderivaten zur herstellung eines arzneimittels zur senkung des blutdrucks.
AU536438B2 (en) Ophthalmic compositions
GB1252329A (enExample)
GB1530299A (en) Amino-substituted tetracyclic compounds
DE69210286D1 (de) Behandlung von intraocularem Druck mit einer synergistischen Kombination
GB1530848A (en) 2-(phenylalkylhydrazono)-propionic acid derivatives
ES483532A1 (es) Procedimiento para la obtencion de derivados de acido a-ami-nofenilacetico.
ES8401952A1 (es) Un procedimiento para preparar nuevos derivados de 1,4-benzotiazina.
ITMI931418A1 (it) Enantiomeri farmacologicamente attivi
SE8502007D0 (sv) Cyklopentanderivat och sett for framstellning derav
FR2414048A1 (fr) Benzofuro (2,3-c) pyridines, leur procede de preparation et leur application en therapeutique
GB1265053A (enExample)
EP0527748A4 (en) Use of prostaglandin f 3 alpha as an ocular hypotensive agent
GB1495890A (en) Thioxanthenecarboxylic acid derivative
ES2037615A1 (es) Procedimiento de preparacion de acido 1,1-dioxo penicilanico, de sus esteres y sales.
HUT40067A (en) Process for producing benzoic acid derivatives and pharmaceutical compositions containing them as active agents