JPS56128781A - 2-oxo-imidazo(1,2-a)pyridine-3-spiro-4'-piperidine - Google Patents
2-oxo-imidazo(1,2-a)pyridine-3-spiro-4'-piperidineInfo
- Publication number
- JPS56128781A JPS56128781A JP3224780A JP3224780A JPS56128781A JP S56128781 A JPS56128781 A JP S56128781A JP 3224780 A JP3224780 A JP 3224780A JP 3224780 A JP3224780 A JP 3224780A JP S56128781 A JPS56128781 A JP S56128781A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- imidazo
- spiro
- piperidine
- oxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
NEW MATERIAL:A 2-oxo-imidazo[1,2-a]pyridine-3-spiro-4'-piperidine of formula I (R1 and R2 are H or group which may link to form single bond).
EXAMPLE: 1,2,3,5,6,7-Hexahydro-2-oxo-imidazo[1.2-a]pyridine-3-spiro-4'-piperidine.
USE: A synthetic intermediate for a psychotropic agent and a medicine and useful as a raw material for an analgesic and anti-inflammatory agent, etc.
PROCESS: 1-Benzyl-4-carbamoyl-4-piperidinopiperidine in an aqueous solution is boiled with palladium carbon under refluxing to give the titled compound of formula I. The reaction proceeds only by using a reusable catalyst, water and air and is industrially excellent. According to the reaction formula, a compound of formula II [R is group of formula III or IV (X1, X2 and X3 are H, halogen, etc.; Y is N, NCO, etc.; Z1 and Z2 are H, methylene, etc.); A is alkylene] useful as a psychotropic agent can be obtained.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55032247A JPS6043069B2 (en) | 1980-03-13 | 1980-03-13 | 2-oxo-imidazo[1,2-a]pyridine-3-spiro-4'-piperidines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55032247A JPS6043069B2 (en) | 1980-03-13 | 1980-03-13 | 2-oxo-imidazo[1,2-a]pyridine-3-spiro-4'-piperidines |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56128781A true JPS56128781A (en) | 1981-10-08 |
JPS6043069B2 JPS6043069B2 (en) | 1985-09-26 |
Family
ID=12353670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55032247A Expired JPS6043069B2 (en) | 1980-03-13 | 1980-03-13 | 2-oxo-imidazo[1,2-a]pyridine-3-spiro-4'-piperidines |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6043069B2 (en) |
-
1980
- 1980-03-13 JP JP55032247A patent/JPS6043069B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS6043069B2 (en) | 1985-09-26 |
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