JPS56128781A - 2-oxo-imidazo(1,2-a)pyridine-3-spiro-4'-piperidine - Google Patents

2-oxo-imidazo(1,2-a)pyridine-3-spiro-4'-piperidine

Info

Publication number
JPS56128781A
JPS56128781A JP3224780A JP3224780A JPS56128781A JP S56128781 A JPS56128781 A JP S56128781A JP 3224780 A JP3224780 A JP 3224780A JP 3224780 A JP3224780 A JP 3224780A JP S56128781 A JPS56128781 A JP S56128781A
Authority
JP
Japan
Prior art keywords
formula
imidazo
spiro
piperidine
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3224780A
Other languages
Japanese (ja)
Other versions
JPS6043069B2 (en
Inventor
Chiaki Tashiro
Kazuki Morikawa
Keiji Aosa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP55032247A priority Critical patent/JPS6043069B2/en
Publication of JPS56128781A publication Critical patent/JPS56128781A/en
Publication of JPS6043069B2 publication Critical patent/JPS6043069B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

NEW MATERIAL:A 2-oxo-imidazo[1,2-a]pyridine-3-spiro-4'-piperidine of formula I (R1 and R2 are H or group which may link to form single bond).
EXAMPLE: 1,2,3,5,6,7-Hexahydro-2-oxo-imidazo[1.2-a]pyridine-3-spiro-4'-piperidine.
USE: A synthetic intermediate for a psychotropic agent and a medicine and useful as a raw material for an analgesic and anti-inflammatory agent, etc.
PROCESS: 1-Benzyl-4-carbamoyl-4-piperidinopiperidine in an aqueous solution is boiled with palladium carbon under refluxing to give the titled compound of formula I. The reaction proceeds only by using a reusable catalyst, water and air and is industrially excellent. According to the reaction formula, a compound of formula II [R is group of formula III or IV (X1, X2 and X3 are H, halogen, etc.; Y is N, NCO, etc.; Z1 and Z2 are H, methylene, etc.); A is alkylene] useful as a psychotropic agent can be obtained.
COPYRIGHT: (C)1981,JPO&Japio
JP55032247A 1980-03-13 1980-03-13 2-oxo-imidazo[1,2-a]pyridine-3-spiro-4'-piperidines Expired JPS6043069B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55032247A JPS6043069B2 (en) 1980-03-13 1980-03-13 2-oxo-imidazo[1,2-a]pyridine-3-spiro-4'-piperidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55032247A JPS6043069B2 (en) 1980-03-13 1980-03-13 2-oxo-imidazo[1,2-a]pyridine-3-spiro-4'-piperidines

Publications (2)

Publication Number Publication Date
JPS56128781A true JPS56128781A (en) 1981-10-08
JPS6043069B2 JPS6043069B2 (en) 1985-09-26

Family

ID=12353670

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55032247A Expired JPS6043069B2 (en) 1980-03-13 1980-03-13 2-oxo-imidazo[1,2-a]pyridine-3-spiro-4'-piperidines

Country Status (1)

Country Link
JP (1) JPS6043069B2 (en)

Also Published As

Publication number Publication date
JPS6043069B2 (en) 1985-09-26

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