JPS56127368A - Piperazinylalkoxyindanes and their acid addition salts - Google Patents
Piperazinylalkoxyindanes and their acid addition saltsInfo
- Publication number
- JPS56127368A JPS56127368A JP3006280A JP3006280A JPS56127368A JP S56127368 A JPS56127368 A JP S56127368A JP 3006280 A JP3006280 A JP 3006280A JP 3006280 A JP3006280 A JP 3006280A JP S56127368 A JPS56127368 A JP S56127368A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- halogen
- phenyl
- acid addition
- compound shown
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A piperazinylalkoxy-indane shown by the formula I (n is 3 or 4; R1 is halogen, alkyl, alkoxy, hydroxy, phenyl, or nitro; R2 is phenyl which may be substituted by halogen, trifluoromethyl, alkoxy, etc.) and its acid addition salt.
EXAMPLE: 6-Fluoro-5-[3-(4-phenyl-1-piperazinyl)propoxy]indane.
USE: A drug having antianxiety actions. Having low toxicity, weakly muscle relaxing action, and high safety.
PROCESS: A halogenoalkoxyindane shown by the formula II (X is halogen) is reacted wit a piperazine shown by the formula III in an inert solvent, e.g., water, dioxane, etc. at room temperature to 150°C, to give a compound shown by the formula I. The amount of the compound shown by the formula III used is preferably 1W 10mol based on 1mol compound shown by the formula II.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3006280A JPS56127368A (en) | 1980-03-10 | 1980-03-10 | Piperazinylalkoxyindanes and their acid addition salts |
US06/157,341 US4339580A (en) | 1979-06-26 | 1980-06-09 | Piperazinylalkoxyindanes and acid addition salts thereof |
DE8080103462T DE3060445D1 (en) | 1979-06-26 | 1980-06-20 | Piperazinylalkoxyindanes and acid addition salts thereof |
EP80103462A EP0021368B1 (en) | 1979-06-26 | 1980-06-20 | Piperazinylalkoxyindanes and acid addition salts thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3006280A JPS56127368A (en) | 1980-03-10 | 1980-03-10 | Piperazinylalkoxyindanes and their acid addition salts |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56127368A true JPS56127368A (en) | 1981-10-06 |
JPH0118073B2 JPH0118073B2 (en) | 1989-04-03 |
Family
ID=12293320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3006280A Granted JPS56127368A (en) | 1979-06-26 | 1980-03-10 | Piperazinylalkoxyindanes and their acid addition salts |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56127368A (en) |
-
1980
- 1980-03-10 JP JP3006280A patent/JPS56127368A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPH0118073B2 (en) | 1989-04-03 |
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