JPS56127368A - Piperazinylalkoxyindanes and their acid addition salts - Google Patents

Piperazinylalkoxyindanes and their acid addition salts

Info

Publication number
JPS56127368A
JPS56127368A JP3006280A JP3006280A JPS56127368A JP S56127368 A JPS56127368 A JP S56127368A JP 3006280 A JP3006280 A JP 3006280A JP 3006280 A JP3006280 A JP 3006280A JP S56127368 A JPS56127368 A JP S56127368A
Authority
JP
Japan
Prior art keywords
formula
halogen
phenyl
acid addition
compound shown
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3006280A
Other languages
Japanese (ja)
Other versions
JPH0118073B2 (en
Inventor
Ryoji Kikumoto
Akihiro Tobe
Jiichi Fukami
Mitsuo Egawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP3006280A priority Critical patent/JPS56127368A/en
Priority to US06/157,341 priority patent/US4339580A/en
Priority to DE8080103462T priority patent/DE3060445D1/en
Priority to EP80103462A priority patent/EP0021368B1/en
Publication of JPS56127368A publication Critical patent/JPS56127368A/en
Publication of JPH0118073B2 publication Critical patent/JPH0118073B2/ja
Granted legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A piperazinylalkoxy-indane shown by the formula I (n is 3 or 4; R1 is halogen, alkyl, alkoxy, hydroxy, phenyl, or nitro; R2 is phenyl which may be substituted by halogen, trifluoromethyl, alkoxy, etc.) and its acid addition salt.
EXAMPLE: 6-Fluoro-5-[3-(4-phenyl-1-piperazinyl)propoxy]indane.
USE: A drug having antianxiety actions. Having low toxicity, weakly muscle relaxing action, and high safety.
PROCESS: A halogenoalkoxyindane shown by the formula II (X is halogen) is reacted wit a piperazine shown by the formula III in an inert solvent, e.g., water, dioxane, etc. at room temperature to 150°C, to give a compound shown by the formula I. The amount of the compound shown by the formula III used is preferably 1W 10mol based on 1mol compound shown by the formula II.
COPYRIGHT: (C)1981,JPO&Japio
JP3006280A 1979-06-26 1980-03-10 Piperazinylalkoxyindanes and their acid addition salts Granted JPS56127368A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP3006280A JPS56127368A (en) 1980-03-10 1980-03-10 Piperazinylalkoxyindanes and their acid addition salts
US06/157,341 US4339580A (en) 1979-06-26 1980-06-09 Piperazinylalkoxyindanes and acid addition salts thereof
DE8080103462T DE3060445D1 (en) 1979-06-26 1980-06-20 Piperazinylalkoxyindanes and acid addition salts thereof
EP80103462A EP0021368B1 (en) 1979-06-26 1980-06-20 Piperazinylalkoxyindanes and acid addition salts thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3006280A JPS56127368A (en) 1980-03-10 1980-03-10 Piperazinylalkoxyindanes and their acid addition salts

Publications (2)

Publication Number Publication Date
JPS56127368A true JPS56127368A (en) 1981-10-06
JPH0118073B2 JPH0118073B2 (en) 1989-04-03

Family

ID=12293320

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3006280A Granted JPS56127368A (en) 1979-06-26 1980-03-10 Piperazinylalkoxyindanes and their acid addition salts

Country Status (1)

Country Link
JP (1) JPS56127368A (en)

Also Published As

Publication number Publication date
JPH0118073B2 (en) 1989-04-03

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