JPS56115773A - Phthalimide derivative - Google Patents

Phthalimide derivative

Info

Publication number
JPS56115773A
JPS56115773A JP1933380A JP1933380A JPS56115773A JP S56115773 A JPS56115773 A JP S56115773A JP 1933380 A JP1933380 A JP 1933380A JP 1933380 A JP1933380 A JP 1933380A JP S56115773 A JPS56115773 A JP S56115773A
Authority
JP
Japan
Prior art keywords
formula
lower alkyl
phthalimide derivative
derivative
anticholesterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1933380A
Other languages
Japanese (ja)
Inventor
Kanji Noda
Akira Nakagawa
Toshiharu Motomura
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP1933380A priority Critical patent/JPS56115773A/en
Publication of JPS56115773A publication Critical patent/JPS56115773A/en
Pending legal-status Critical Current

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  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A phthalimide derivative expressed by formula I (R is H or lower alkyl; R1, R2, R3 and R4 are H, lower alkyl, lower alkoxy, halogen, nitro, carboxyl or lower alkoxycarbonyl).
EXAMPLE: N-[trans-4-(Carboxy)cyclohexylmethyl]-3-nitrophthalimide.
USE: A preventing or treating agent against allergic diseases, e.g. nephritis, rheumatism, collagen disease or autoimmune diseases having a remarkable anticomplementary action or a medicine having antiplasmin, antitumor, antiulcer, antithrombotic and anticholesterol actions.
PROCESS: A phthalic anhydride derivative of formula II is heated with tranexamic acid of formula III in glacial acetic acid to give the compound of formula I in high yield.
COPYRIGHT: (C)1981,JPO&Japio
JP1933380A 1980-02-18 1980-02-18 Phthalimide derivative Pending JPS56115773A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1933380A JPS56115773A (en) 1980-02-18 1980-02-18 Phthalimide derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1933380A JPS56115773A (en) 1980-02-18 1980-02-18 Phthalimide derivative

Publications (1)

Publication Number Publication Date
JPS56115773A true JPS56115773A (en) 1981-09-11

Family

ID=11996474

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1933380A Pending JPS56115773A (en) 1980-02-18 1980-02-18 Phthalimide derivative

Country Status (1)

Country Link
JP (1) JPS56115773A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998052919A1 (en) * 1997-05-21 1998-11-26 Japan Tobacco Inc. Phthalimide derivatives and pharmaceutical containing said derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998052919A1 (en) * 1997-05-21 1998-11-26 Japan Tobacco Inc. Phthalimide derivatives and pharmaceutical containing said derivatives

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