JPS5592355A - Enzyme-adsorbing substance and purification of enzyme using the same - Google Patents

Enzyme-adsorbing substance and purification of enzyme using the same

Info

Publication number
JPS5592355A
JPS5592355A JP15754278A JP15754278A JPS5592355A JP S5592355 A JPS5592355 A JP S5592355A JP 15754278 A JP15754278 A JP 15754278A JP 15754278 A JP15754278 A JP 15754278A JP S5592355 A JPS5592355 A JP S5592355A
Authority
JP
Japan
Prior art keywords
compound
enzyme
formula
adsorbing substance
purification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15754278A
Other languages
Japanese (ja)
Inventor
Daigaku Takiguchi
Eiji Ito
Hiroaki Nakamura
Izumi Kumita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Soda Co Ltd
Original Assignee
Nippon Soda Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Soda Co Ltd filed Critical Nippon Soda Co Ltd
Priority to JP15754278A priority Critical patent/JPS5592355A/en
Publication of JPS5592355A publication Critical patent/JPS5592355A/en
Pending legal-status Critical Current

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  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:Amidine or guanidine compound of formula I [X is NH2 or COOH; A is 1W4C alkylene or phenylene; R is a group of formula II or formula III (γ1Wγ3 are H or lower alkyl], and a water-insoluble carrier bonded with the above compound directly or through a binder.
EXAMPLE: 2-(4-Aminophenoxy)acetamidine hydrochloride.
USE: Enzyme-adsorbing substance and its raw material, having a specific affinity with enzymes, e.g. urokinase, trypsin, kallikrein, etc. Useful for the purification of the above enzymes.
PROCESS: For example, a compound of formula I such as a compound of formula V can be obtained from a compound of formula IV. The compound obtained is then bonded with a water-insoluble carrier (preferably agarose) directly or through a bonding compound to given an enzyme-adsorbing substance.
COPYRIGHT: (C)1980,JPO&Japio
JP15754278A 1978-12-22 1978-12-22 Enzyme-adsorbing substance and purification of enzyme using the same Pending JPS5592355A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15754278A JPS5592355A (en) 1978-12-22 1978-12-22 Enzyme-adsorbing substance and purification of enzyme using the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15754278A JPS5592355A (en) 1978-12-22 1978-12-22 Enzyme-adsorbing substance and purification of enzyme using the same

Publications (1)

Publication Number Publication Date
JPS5592355A true JPS5592355A (en) 1980-07-12

Family

ID=15651947

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15754278A Pending JPS5592355A (en) 1978-12-22 1978-12-22 Enzyme-adsorbing substance and purification of enzyme using the same

Country Status (1)

Country Link
JP (1) JPS5592355A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59109172A (en) * 1982-12-13 1984-06-23 Ss Pharmaceut Co Ltd Purification of kallikrein
JPS6485077A (en) * 1987-09-25 1989-03-30 Takara Shuzo Co Purification of arginine residue-specific endopeptidase

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59109172A (en) * 1982-12-13 1984-06-23 Ss Pharmaceut Co Ltd Purification of kallikrein
JPH0260316B2 (en) * 1982-12-13 1990-12-14 Ss Pharmaceutical Co
JPS6485077A (en) * 1987-09-25 1989-03-30 Takara Shuzo Co Purification of arginine residue-specific endopeptidase

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