JPS5587779A - Epoxyditerpene - Google Patents

Epoxyditerpene

Info

Publication number
JPS5587779A
JPS5587779A JP16077178A JP16077178A JPS5587779A JP S5587779 A JPS5587779 A JP S5587779A JP 16077178 A JP16077178 A JP 16077178A JP 16077178 A JP16077178 A JP 16077178A JP S5587779 A JPS5587779 A JP S5587779A
Authority
JP
Japan
Prior art keywords
compound
formula
react
day
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16077178A
Other languages
Japanese (ja)
Other versions
JPS6154028B2 (en
Inventor
Tadahiro Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP16077178A priority Critical patent/JPS5587779A/en
Publication of JPS5587779A publication Critical patent/JPS5587779A/en
Publication of JPS6154028B2 publication Critical patent/JPS6154028B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:1β-Acetoxy-13, 14β-epoxy-2β-( 1-hydroxy-1-methylethyl )5, 9, 13α-trimethylcyclotetradecane-5,9-diene of formula I (Ac is acetyl).
USE: A medicine having carcinostatic acitivity. The dosage is about 5W3000mg/kg, preferably about 25W1000mg/kg.day in portions and it is orally or nonorally administered twice to five times a day.
PREPARATION: 2β-Isopropenyl-5, 9, 13-trimethylcyclotetradeca-5, 9, 13-trien-1β- ol is epoxidized with t-butylhydroperoxide in the presence of vanadyl acetoacetonate and the product is made to react with acetic anhydride to give a compound of formula III. Pyridine hydrochloride is made to react with the compound of formula III to form a compound of formula IV, which is made to react with tri-n-butyltin hydride to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP16077178A 1978-12-26 1978-12-26 Epoxyditerpene Granted JPS5587779A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16077178A JPS5587779A (en) 1978-12-26 1978-12-26 Epoxyditerpene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16077178A JPS5587779A (en) 1978-12-26 1978-12-26 Epoxyditerpene

Publications (2)

Publication Number Publication Date
JPS5587779A true JPS5587779A (en) 1980-07-02
JPS6154028B2 JPS6154028B2 (en) 1986-11-20

Family

ID=15722093

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16077178A Granted JPS5587779A (en) 1978-12-26 1978-12-26 Epoxyditerpene

Country Status (1)

Country Link
JP (1) JPS5587779A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1351678A2 (en) * 2001-01-02 2003-10-15 Elizabeth Shanahan-Prendergast Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1351678A2 (en) * 2001-01-02 2003-10-15 Elizabeth Shanahan-Prendergast Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens

Also Published As

Publication number Publication date
JPS6154028B2 (en) 1986-11-20

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