JPS5587779A - Epoxyditerpene - Google Patents
EpoxyditerpeneInfo
- Publication number
- JPS5587779A JPS5587779A JP16077178A JP16077178A JPS5587779A JP S5587779 A JPS5587779 A JP S5587779A JP 16077178 A JP16077178 A JP 16077178A JP 16077178 A JP16077178 A JP 16077178A JP S5587779 A JPS5587779 A JP S5587779A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- react
- day
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:1β-Acetoxy-13, 14β-epoxy-2β-( 1-hydroxy-1-methylethyl )5, 9, 13α-trimethylcyclotetradecane-5,9-diene of formula I (Ac is acetyl).
USE: A medicine having carcinostatic acitivity. The dosage is about 5W3000mg/kg, preferably about 25W1000mg/kg.day in portions and it is orally or nonorally administered twice to five times a day.
PREPARATION: 2β-Isopropenyl-5, 9, 13-trimethylcyclotetradeca-5, 9, 13-trien-1β- ol is epoxidized with t-butylhydroperoxide in the presence of vanadyl acetoacetonate and the product is made to react with acetic anhydride to give a compound of formula III. Pyridine hydrochloride is made to react with the compound of formula III to form a compound of formula IV, which is made to react with tri-n-butyltin hydride to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16077178A JPS5587779A (en) | 1978-12-26 | 1978-12-26 | Epoxyditerpene |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16077178A JPS5587779A (en) | 1978-12-26 | 1978-12-26 | Epoxyditerpene |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5587779A true JPS5587779A (en) | 1980-07-02 |
JPS6154028B2 JPS6154028B2 (en) | 1986-11-20 |
Family
ID=15722093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16077178A Granted JPS5587779A (en) | 1978-12-26 | 1978-12-26 | Epoxyditerpene |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5587779A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1351678A2 (en) * | 2001-01-02 | 2003-10-15 | Elizabeth Shanahan-Prendergast | Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens |
-
1978
- 1978-12-26 JP JP16077178A patent/JPS5587779A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1351678A2 (en) * | 2001-01-02 | 2003-10-15 | Elizabeth Shanahan-Prendergast | Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens |
Also Published As
Publication number | Publication date |
---|---|
JPS6154028B2 (en) | 1986-11-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2059603C1 (en) | Derivatives of &&&-substituted arylacetic acids and pharmaceutical composition | |
JPS52283A (en) | Process for preparation of carbostyril derivatives | |
JPS5587779A (en) | Epoxyditerpene | |
JPS52282A (en) | Process for preparation of carbostyril derivatives | |
JPS57106618A (en) | Anticancer agent consisting of polyprenyl compound | |
JPS57193473A (en) | Vitamin e linoleic acid ester | |
JPS55122715A (en) | Antidiabetic agent | |
JPS51136676A (en) | Process for preparation of carbostyril derivatives | |
JPS5668672A (en) | Novel 2-acetoxybenzamide derviative, its preparation, and pharmaceutical containing said derviative as effective component | |
JPS525769A (en) | Preparation of 3-substituted pyrolidine derivatives | |
JPS5711985A (en) | Protoporphyrin dimethyl ester germanium complex and its preparation | |
JPS57112400A (en) | Sterol saccharide and drug containing the same | |
JPS5764639A (en) | Novel stilbene derivative, its preparation, and medical composition containing the same as active ingredent | |
JPS5223058A (en) | Preparation of indanylpropionic acid derivatives | |
JPS55122719A (en) | Medicine composition having antipyretic, analgesic, and anti-inflammatory action | |
JPS51139694A (en) | Process for producing 'miso' | |
JPS56156290A (en) | Organosilicon compound | |
JPS5248670A (en) | Preparation of 2,5-disubstituted-pyridine derivatives | |
JPS55133311A (en) | Novel antiallergic agent | |
JPS57156434A (en) | Zinc indanecarboxylate | |
JPS5625166A (en) | 5-fluorouracil derivative | |
JPS5519226A (en) | 5-acyloxymethylindazole derivative, its preparation, and preparation including the same | |
JPS57212137A (en) | Preparation of phenyl aliphtic acid derivative | |
JPS55157574A (en) | 5-fluorouracyl derivative and its preparation | |
JPS5444696A (en) | Condensed isoxazole compound and its preparation |