JPS5576847A - (2s,3r)-and (2r,3r)-3-amino-2-hydroxy-5-methylhexanoic acid, its derivative, and their preparation - Google Patents

(2s,3r)-and (2r,3r)-3-amino-2-hydroxy-5-methylhexanoic acid, its derivative, and their preparation

Info

Publication number
JPS5576847A
JPS5576847A JP14785078A JP14785078A JPS5576847A JP S5576847 A JPS5576847 A JP S5576847A JP 14785078 A JP14785078 A JP 14785078A JP 14785078 A JP14785078 A JP 14785078A JP S5576847 A JPS5576847 A JP S5576847A
Authority
JP
Japan
Prior art keywords
hydroxy
amino
derivative
methylhexanoic acid
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14785078A
Other languages
Japanese (ja)
Inventor
Hamao Umezawa
Takaaki Aoyanagi
Tetsuyuki Saino
Kenji Seya
Rinzo Nishizawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP14785078A priority Critical patent/JPS5576847A/en
Publication of JPS5576847A publication Critical patent/JPS5576847A/en
Pending legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:( 2S,3R )-and ( 2R,3R )-3-Amino-2-hydroxy-5-methylhexanoic acid of the formula (R is H or benzyloxycarbonyl) and its derivative.
USE: Intermediate of the immunostimulator, amastacin. Has an asymmetry center at the 2-position of 3-amino-2-hydroxy-5-methylhexane derivative.
PROCESS: ( 2RS, 3R )-N-Benzyloxycarbonyl-3-amino-2-hydroxy-5-methylhexanoic acid and substantially equivalent amount of burcine are dissolved in a hot organic solvent, e.g. lower alcohol, to deposit crystals, from which brucine salt is then removed. The residue obtained is crystallized to give a compound of the formula.
COPYRIGHT: (C)1980,JPO&Japio
JP14785078A 1978-12-01 1978-12-01 (2s,3r)-and (2r,3r)-3-amino-2-hydroxy-5-methylhexanoic acid, its derivative, and their preparation Pending JPS5576847A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14785078A JPS5576847A (en) 1978-12-01 1978-12-01 (2s,3r)-and (2r,3r)-3-amino-2-hydroxy-5-methylhexanoic acid, its derivative, and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14785078A JPS5576847A (en) 1978-12-01 1978-12-01 (2s,3r)-and (2r,3r)-3-amino-2-hydroxy-5-methylhexanoic acid, its derivative, and their preparation

Publications (1)

Publication Number Publication Date
JPS5576847A true JPS5576847A (en) 1980-06-10

Family

ID=15439660

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14785078A Pending JPS5576847A (en) 1978-12-01 1978-12-01 (2s,3r)-and (2r,3r)-3-amino-2-hydroxy-5-methylhexanoic acid, its derivative, and their preparation

Country Status (1)

Country Link
JP (1) JPS5576847A (en)

Similar Documents

Publication Publication Date Title
JPS5576847A (en) (2s,3r)-and (2r,3r)-3-amino-2-hydroxy-5-methylhexanoic acid, its derivative, and their preparation
JPS5536403A (en) Preparation of 1-benzazonine derivative
DK527483A (en) PROCEDURE FOR THE PREPARATION OF BENZAZEPINE DERIVATIVES
JPS51142098A (en) A process for preparing a polyester
JPS53127891A (en) Crystallization of co-enzyme q
DE2962281D1 (en) Substituted 2-phenylamino-3,4,5,6-tetrahydropyrimidines, their acid addition salts, medicines containing them and process for their preparation
JPS5511547A (en) Thiazolidine derivative
JPS5432480A (en) Novel preparation of piperidine derivatives
JPS5419985A (en) Production of hydroxycarbostyril derivative
JPS5538363A (en) Preparation of optically active n-mercaptoacyl-imino acid
JPS5557566A (en) N-methyl-8-chloro-3,4-dihydro-2-quinolinone, its preparation, and germicide containing the same
JPS557221A (en) Preparation of alethine derivative
JPS5540614A (en) Preparation of optically active n-mercaptoacyl-imino acid
JPS5553299A (en) N2-substituted-phenyl-2,6-diaminonebularine
JPS54109969A (en) Novel method of preparing thiazole derivative
JPS5219622A (en) Process for preparation of tartaric acid salts
JPS51122066A (en) Process for preparation of heterocyclic compounds
JPS53149975A (en) Preparation of imidazolylbenzophenones
JPS5231093A (en) Preparation of 3- methylenecephalosporanic acid derivatives
JPS5239665A (en) Process for preparing perfluorolactones
JPS53112868A (en) Production of thienylacetic acid derivative
JPS572271A (en) Preparation of 2-aminoindolenine derivative
JPS549225A (en) Preparation of hydrazinoalkanesulfonic acid derivatives
JPS5452055A (en) Optical resolution of n-sulfonyldiarylsulfylimines
JPS51138680A (en) Process for preparing dibenzopyrans.