JPS5555186A - Preparation of indole derivative - Google Patents

Preparation of indole derivative

Info

Publication number
JPS5555186A
JPS5555186A JP12321278A JP12321278A JPS5555186A JP S5555186 A JPS5555186 A JP S5555186A JP 12321278 A JP12321278 A JP 12321278A JP 12321278 A JP12321278 A JP 12321278A JP S5555186 A JPS5555186 A JP S5555186A
Authority
JP
Japan
Prior art keywords
compound
indole derivative
preparation
reducing
pyride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12321278A
Other languages
Japanese (ja)
Other versions
JPS5936918B2 (en
Inventor
Shingo Matsumura
Hiroshi Enomoto
Yoshiaki Aoyanagi
Sumitsugu Nomiyama
Tatsuhiko Kono
Masato Matsuda
Haruo Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Priority to JP12321278A priority Critical patent/JPS5936918B2/en
Publication of JPS5555186A publication Critical patent/JPS5555186A/en
Publication of JPS5936918B2 publication Critical patent/JPS5936918B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To prepare an indole derivative useful as a xanthine oxidase inhibitor, by reducing a 1-carboalkoxy-9H-pyride[3,4-b]indole derivative with a reducing agent.
CONSTITUTION: A compound I (R1,2 are H, OH, or acyloxy; R3 is lower alkyl) is reduced with an organic metal hydride (e.g. diisobutyl aluminum hydride) at low temperature to afford a compound II. The compound I (wherein R1=OH, R2=H and R3=CH3) and the compound II (wherein R1=OH, and R2=H) can also be extracted from Picrasma quassioides Benn.
COPYRIGHT: (C)1980,JPO&Japio
JP12321278A 1978-10-05 1978-10-05 Method for producing indole derivatives Expired JPS5936918B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12321278A JPS5936918B2 (en) 1978-10-05 1978-10-05 Method for producing indole derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12321278A JPS5936918B2 (en) 1978-10-05 1978-10-05 Method for producing indole derivatives

Publications (2)

Publication Number Publication Date
JPS5555186A true JPS5555186A (en) 1980-04-22
JPS5936918B2 JPS5936918B2 (en) 1984-09-06

Family

ID=14854965

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12321278A Expired JPS5936918B2 (en) 1978-10-05 1978-10-05 Method for producing indole derivatives

Country Status (1)

Country Link
JP (1) JPS5936918B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0522024Y2 (en) * 1985-12-23 1993-06-07

Also Published As

Publication number Publication date
JPS5936918B2 (en) 1984-09-06

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