JPS57120584A - Production of catechin derivative - Google Patents
Production of catechin derivativeInfo
- Publication number
- JPS57120584A JPS57120584A JP746981A JP746981A JPS57120584A JP S57120584 A JPS57120584 A JP S57120584A JP 746981 A JP746981 A JP 746981A JP 746981 A JP746981 A JP 746981A JP S57120584 A JPS57120584 A JP S57120584A
- Authority
- JP
- Japan
- Prior art keywords
- positions
- catechin
- variety
- compound
- produce
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pyrane Compounds (AREA)
Abstract
PURPOSE: Selective acylation is effected in 5 and 7 positions of catechin in the presence of boric acid under a basic condition, when necessary, further acylation in 3 and/or 3', 4' positions is conducted to produce a catechin derivative used for a variety of purposes such as carcinostatic agent.
CONSTITUTION: An acylating agent is made to act on catechin of formulaIin the presence of boric acid under a basic condition to prepare 5,7-O-diacylcatechin of formula II (R1 is acyl residue of organic carboxyl, carbonylic or sulfonic acid). Further, when necessary, the hydroxyls in 3 and/or 3', 4' positions in the compound of formulaIa are converted into O-acyls or O-alkyls to produce a compound of formula III (R2, R3 are the same group in R1, alkyl or substituted alkyl, H). The process readily gives a variety of catechin derivatives having different substituents in the 5, 7 positions from in 3', 4' positions.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP746981A JPS57120584A (en) | 1981-01-20 | 1981-01-20 | Production of catechin derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP746981A JPS57120584A (en) | 1981-01-20 | 1981-01-20 | Production of catechin derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57120584A true JPS57120584A (en) | 1982-07-27 |
Family
ID=11666650
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP746981A Pending JPS57120584A (en) | 1981-01-20 | 1981-01-20 | Production of catechin derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57120584A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997041137A1 (en) * | 1996-04-17 | 1997-11-06 | Unifob | Use of anthocyanidin and anthocyanidin derivatives |
JP2008509939A (en) * | 2004-08-19 | 2008-04-03 | ザ・ホンコン・ポリテクニック・ユニバーシティ | (-)-Epigallocatechin gallate derivative for inhibiting proteasome |
-
1981
- 1981-01-20 JP JP746981A patent/JPS57120584A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997041137A1 (en) * | 1996-04-17 | 1997-11-06 | Unifob | Use of anthocyanidin and anthocyanidin derivatives |
JP2008509939A (en) * | 2004-08-19 | 2008-04-03 | ザ・ホンコン・ポリテクニック・ユニバーシティ | (-)-Epigallocatechin gallate derivative for inhibiting proteasome |
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