JPS5549381A - 1-(3-hydroxypropyl)-3, 7-dimethylxanthine and its preparation - Google Patents

1-(3-hydroxypropyl)-3, 7-dimethylxanthine and its preparation

Info

Publication number
JPS5549381A
JPS5549381A JP12298878A JP12298878A JPS5549381A JP S5549381 A JPS5549381 A JP S5549381A JP 12298878 A JP12298878 A JP 12298878A JP 12298878 A JP12298878 A JP 12298878A JP S5549381 A JPS5549381 A JP S5549381A
Authority
JP
Japan
Prior art keywords
dimethylxanthine
hydroxypropyl
preparation
formula
lipoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12298878A
Other languages
Japanese (ja)
Inventor
Shigeo Shimizu
Hiroyuki Takano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
SANKEI YAKUHIN KK
Nippon Pharmaceutical Development Institute Co
Original Assignee
NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
SANKEI YAKUHIN KK
Nippon Pharmaceutical Development Institute Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK, SANKEI YAKUHIN KK, Nippon Pharmaceutical Development Institute Co filed Critical NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
Priority to JP12298878A priority Critical patent/JPS5549381A/en
Publication of JPS5549381A publication Critical patent/JPS5549381A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:1-(3-Hydroxypropyl)-3, 7-dimethylxanthine of formula.
USE: Remedy for circulatory disorder, having vascular dilation activity. Since it is easily soluble in lipoid as well as water, it can be easily absorbed through the stomach and the intestines.
PROCESS: The compound of formula is prepared by reacting 3, 7-dimethylxanthine (theobromine) with a 3-halogeno-1-propanol in the presence of an alkali.
COPYRIGHT: (C)1980,JPO&Japio
JP12298878A 1978-10-05 1978-10-05 1-(3-hydroxypropyl)-3, 7-dimethylxanthine and its preparation Pending JPS5549381A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12298878A JPS5549381A (en) 1978-10-05 1978-10-05 1-(3-hydroxypropyl)-3, 7-dimethylxanthine and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12298878A JPS5549381A (en) 1978-10-05 1978-10-05 1-(3-hydroxypropyl)-3, 7-dimethylxanthine and its preparation

Publications (1)

Publication Number Publication Date
JPS5549381A true JPS5549381A (en) 1980-04-09

Family

ID=14849503

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12298878A Pending JPS5549381A (en) 1978-10-05 1978-10-05 1-(3-hydroxypropyl)-3, 7-dimethylxanthine and its preparation

Country Status (1)

Country Link
JP (1) JPS5549381A (en)

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