JPS5519237A - Crystalline lactose with high beta-lactose content and diluent comprising it - Google Patents

Crystalline lactose with high beta-lactose content and diluent comprising it

Info

Publication number
JPS5519237A
JPS5519237A JP9213178A JP9213178A JPS5519237A JP S5519237 A JPS5519237 A JP S5519237A JP 9213178 A JP9213178 A JP 9213178A JP 9213178 A JP9213178 A JP 9213178A JP S5519237 A JPS5519237 A JP S5519237A
Authority
JP
Japan
Prior art keywords
lactose
diluent
crystalline
content
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9213178A
Other languages
Japanese (ja)
Other versions
JPS6144846B2 (en
Inventor
Takeshi Wakimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TOA IYAKUHIN KOGYO KK
Original Assignee
TOA IYAKUHIN KOGYO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TOA IYAKUHIN KOGYO KK filed Critical TOA IYAKUHIN KOGYO KK
Priority to JP9213178A priority Critical patent/JPS5519237A/en
Publication of JPS5519237A publication Critical patent/JPS5519237A/en
Publication of JPS6144846B2 publication Critical patent/JPS6144846B2/ja
Granted legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE: The title lactose useful as an excellent diluent, prepared by growing the crystal of amorphous lactose under specified conditions, and by drying the srystal.
CONSTITUTION: Amorphous lactose is subjected to the atmosphere of RH≥50% to make the crystal growth measured by the X-ray. diffractometry at the diffraction angle 2θ=10.5° in the 110-plane of the β-lactose maximum, and dried to give a crystalline lactose with a high β-lactose content, e.g.≥55 wt.%. The lactose having improved compression moldability is easily prepared and useful as a diluent due to the small increase in volume with moisture absorption.
COPYRIGHT: (C)1980,JPO&Japio
JP9213178A 1978-07-27 1978-07-27 Crystalline lactose with high beta-lactose content and diluent comprising it Granted JPS5519237A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9213178A JPS5519237A (en) 1978-07-27 1978-07-27 Crystalline lactose with high beta-lactose content and diluent comprising it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9213178A JPS5519237A (en) 1978-07-27 1978-07-27 Crystalline lactose with high beta-lactose content and diluent comprising it

Publications (2)

Publication Number Publication Date
JPS5519237A true JPS5519237A (en) 1980-02-09
JPS6144846B2 JPS6144846B2 (en) 1986-10-04

Family

ID=14045868

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9213178A Granted JPS5519237A (en) 1978-07-27 1978-07-27 Crystalline lactose with high beta-lactose content and diluent comprising it

Country Status (1)

Country Link
JP (1) JPS5519237A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6137728A (en) * 1984-07-23 1986-02-22 イーライ・リリー・アンド・カンパニー Improved medicine of ceftazidime
WO2002045682A1 (en) * 2000-12-08 2002-06-13 School Of Pharmacy, University Of London Particulate inhalation carrier
US20120220764A1 (en) * 2000-07-20 2012-08-30 Campina B.V. Method for producing a crystalline tableting additive, additive thus obtained and use thereof
US9365905B2 (en) 2005-02-10 2016-06-14 Dmv-Fonterra Excipients Technology Gmbh Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4885746A (en) * 1972-02-18 1973-11-13
JPS51146411A (en) * 1975-06-10 1976-12-16 Meiji Milk Prod Co Ltd Preparation of beta-lactose

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4885746A (en) * 1972-02-18 1973-11-13
JPS51146411A (en) * 1975-06-10 1976-12-16 Meiji Milk Prod Co Ltd Preparation of beta-lactose

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6137728A (en) * 1984-07-23 1986-02-22 イーライ・リリー・アンド・カンパニー Improved medicine of ceftazidime
US20120220764A1 (en) * 2000-07-20 2012-08-30 Campina B.V. Method for producing a crystalline tableting additive, additive thus obtained and use thereof
US8501236B2 (en) * 2000-07-20 2013-08-06 Campina B.V. Method for producing a crystalline tableting additive, additive thus obtained and use thereof
WO2002045682A1 (en) * 2000-12-08 2002-06-13 School Of Pharmacy, University Of London Particulate inhalation carrier
US9365905B2 (en) 2005-02-10 2016-06-14 Dmv-Fonterra Excipients Technology Gmbh Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom

Also Published As

Publication number Publication date
JPS6144846B2 (en) 1986-10-04

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