JPS5517349A - Production of diterpene derivative - Google Patents

Production of diterpene derivative

Info

Publication number
JPS5517349A
JPS5517349A JP9021078A JP9021078A JPS5517349A JP S5517349 A JPS5517349 A JP S5517349A JP 9021078 A JP9021078 A JP 9021078A JP 9021078 A JP9021078 A JP 9021078A JP S5517349 A JPS5517349 A JP S5517349A
Authority
JP
Japan
Prior art keywords
formula
compound
methanol
nitration
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9021078A
Other languages
Japanese (ja)
Other versions
JPS5653295B2 (en
Inventor
Hiroyuki Akita
Takeshi Oishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN Institute of Physical and Chemical Research
Original Assignee
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN Institute of Physical and Chemical Research filed Critical RIKEN Institute of Physical and Chemical Research
Priority to JP9021078A priority Critical patent/JPS5517349A/en
Publication of JPS5517349A publication Critical patent/JPS5517349A/en
Publication of JPS5653295B2 publication Critical patent/JPS5653295B2/ja
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: Title compound useful as a synthetic intermediate of various kinds of sesquiterpene is readily and inexpensively obtained by the diazotization of 7-oxo-13- amino-derivative in methanol.
CONSTITUTION: A compound of formula (2) is dissolved in a large amount of methanol and the solution is acidified by adding sulfuric acid or the like. Then, sodium nitrite is added and the reaction is effected at room temperature. The methanol is distilled off to 1/4 volume. Water is added to the residue and the mixture is extracted with benzene to give compounds of formula I, II and III. The starting compound of formula (2) is produced by the reduction of l-abietic acid (1) with lithium-aluminum hydride, then nitration with fuming nitric acid-conc. sulfuric acid, and further reduction. Or the nitration of a compound of formula III gives a compound of formula (3), which is subsequently reduced to give the compound of formula (2).
COPYRIGHT: (C)1980,JPO&Japio
JP9021078A 1978-07-24 1978-07-24 Production of diterpene derivative Granted JPS5517349A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9021078A JPS5517349A (en) 1978-07-24 1978-07-24 Production of diterpene derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9021078A JPS5517349A (en) 1978-07-24 1978-07-24 Production of diterpene derivative

Publications (2)

Publication Number Publication Date
JPS5517349A true JPS5517349A (en) 1980-02-06
JPS5653295B2 JPS5653295B2 (en) 1981-12-17

Family

ID=13992113

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9021078A Granted JPS5517349A (en) 1978-07-24 1978-07-24 Production of diterpene derivative

Country Status (1)

Country Link
JP (1) JPS5517349A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7087751B2 (en) 2001-01-18 2006-08-08 Schering Corporation Synthesis of temozolomide and analogs
CN103613490A (en) * 2013-12-11 2014-03-05 中国科学院烟台海岸带研究所 Drop diterpenoid type compound as well as preparation method and application thereof

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58174794U (en) * 1982-05-18 1983-11-22 ホーチキ株式会社 photoelectric smoke detector
JPS6010393U (en) * 1983-07-01 1985-01-24 ホーチキ株式会社 Structure of smoke detection part of scattered light smoke detector
JPS60148688U (en) * 1984-03-09 1985-10-02 ホーチキ株式会社 Scattered light smoke detector
JPS6155787U (en) * 1984-09-19 1986-04-15

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49116051A (en) * 1973-03-12 1974-11-06
JPS5324069A (en) * 1976-08-18 1978-03-06 Okura Kikai Kk Peeling apparatus for food material

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49116051A (en) * 1973-03-12 1974-11-06
JPS5324069A (en) * 1976-08-18 1978-03-06 Okura Kikai Kk Peeling apparatus for food material

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7087751B2 (en) 2001-01-18 2006-08-08 Schering Corporation Synthesis of temozolomide and analogs
US7446209B2 (en) 2001-01-18 2008-11-04 Schering Corporation Synthesis of temozolomide and analogs
CN103613490A (en) * 2013-12-11 2014-03-05 中国科学院烟台海岸带研究所 Drop diterpenoid type compound as well as preparation method and application thereof

Also Published As

Publication number Publication date
JPS5653295B2 (en) 1981-12-17

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