JPS55162760A - Phenylacetamide derivative - Google Patents

Phenylacetamide derivative

Info

Publication number
JPS55162760A
JPS55162760A JP4073579A JP4073579A JPS55162760A JP S55162760 A JPS55162760 A JP S55162760A JP 4073579 A JP4073579 A JP 4073579A JP 4073579 A JP4073579 A JP 4073579A JP S55162760 A JPS55162760 A JP S55162760A
Authority
JP
Japan
Prior art keywords
formula
compound
reacted
integer
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4073579A
Other languages
Japanese (ja)
Other versions
JPS6155498B2 (en
Inventor
Tetsukiyo Kamijo
Ryoji Yamamoto
Masanori Yamaura
Yukiyoshi Ajisawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Priority to JP4073579A priority Critical patent/JPS55162760A/en
Priority to EP80300817A priority patent/EP0017376A1/en
Publication of JPS55162760A publication Critical patent/JPS55162760A/en
Publication of JPS6155498B2 publication Critical patent/JPS6155498B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NEW MATERIAL:A compound of formula I (X is 1W3C alkoxy group; R1 is 1W3C alkyl group; R2 is 1W3C alkyl group, 3W6C alkenyl group, etc.; n is an integer 0W2; m is 0 or 1; l is an integer 3W5), and its salt.
EXAMPLE: N-( 1,2,3,4-Tetrahydro-1-naphthylmethyl )-N-2-( N-methyl-N-tetrahydrofurfurylamino)ethyl-4-methoxyphenylacetamide.
USE: A medicine having a powerful analgesic action.
PROCESS: A compound of formula II is reacted with a phenylacetic acid or its derivative of formula III in an inert organic solvent, e.g. benzene, in the presence of a condensing agent, e.g. phosphorus oxychloride, to give the compound of formula I. The starting compound of formula II can be obtained by the following method: A novel compound of formula IV is reacted with chloroacetyl chloride to give a reaction product, which is then reacted with an amine of the formula R1NH2. The resulting product is reacted with a compound of the formula R2Z (Z is halogen), and then reduced.
COPYRIGHT: (C)1980,JPO&Japio
JP4073579A 1979-03-30 1979-04-04 Phenylacetamide derivative Granted JPS55162760A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP4073579A JPS55162760A (en) 1979-04-04 1979-04-04 Phenylacetamide derivative
EP80300817A EP0017376A1 (en) 1979-03-30 1980-03-18 Phenylacetamide compounds and an analgesic composition containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4073579A JPS55162760A (en) 1979-04-04 1979-04-04 Phenylacetamide derivative

Publications (2)

Publication Number Publication Date
JPS55162760A true JPS55162760A (en) 1980-12-18
JPS6155498B2 JPS6155498B2 (en) 1986-11-28

Family

ID=12588883

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4073579A Granted JPS55162760A (en) 1979-03-30 1979-04-04 Phenylacetamide derivative

Country Status (1)

Country Link
JP (1) JPS55162760A (en)

Also Published As

Publication number Publication date
JPS6155498B2 (en) 1986-11-28

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