JPS55162760A - Phenylacetamide derivative - Google Patents
Phenylacetamide derivativeInfo
- Publication number
- JPS55162760A JPS55162760A JP4073579A JP4073579A JPS55162760A JP S55162760 A JPS55162760 A JP S55162760A JP 4073579 A JP4073579 A JP 4073579A JP 4073579 A JP4073579 A JP 4073579A JP S55162760 A JPS55162760 A JP S55162760A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- reacted
- integer
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
NEW MATERIAL:A compound of formula I (X is 1W3C alkoxy group; R1 is 1W3C alkyl group; R2 is 1W3C alkyl group, 3W6C alkenyl group, etc.; n is an integer 0W2; m is 0 or 1; l is an integer 3W5), and its salt.
EXAMPLE: N-( 1,2,3,4-Tetrahydro-1-naphthylmethyl )-N-2-( N-methyl-N-tetrahydrofurfurylamino)ethyl-4-methoxyphenylacetamide.
USE: A medicine having a powerful analgesic action.
PROCESS: A compound of formula II is reacted with a phenylacetic acid or its derivative of formula III in an inert organic solvent, e.g. benzene, in the presence of a condensing agent, e.g. phosphorus oxychloride, to give the compound of formula I. The starting compound of formula II can be obtained by the following method: A novel compound of formula IV is reacted with chloroacetyl chloride to give a reaction product, which is then reacted with an amine of the formula R1NH2. The resulting product is reacted with a compound of the formula R2Z (Z is halogen), and then reduced.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4073579A JPS55162760A (en) | 1979-04-04 | 1979-04-04 | Phenylacetamide derivative |
EP80300817A EP0017376A1 (en) | 1979-03-30 | 1980-03-18 | Phenylacetamide compounds and an analgesic composition containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4073579A JPS55162760A (en) | 1979-04-04 | 1979-04-04 | Phenylacetamide derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55162760A true JPS55162760A (en) | 1980-12-18 |
JPS6155498B2 JPS6155498B2 (en) | 1986-11-28 |
Family
ID=12588883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4073579A Granted JPS55162760A (en) | 1979-03-30 | 1979-04-04 | Phenylacetamide derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55162760A (en) |
-
1979
- 1979-04-04 JP JP4073579A patent/JPS55162760A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6155498B2 (en) | 1986-11-28 |
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