JPS5515401A - 1-substituted-2-4-(1-oxo-2-isoindolinyl)phenyl-propyl alcohol and their preparation - Google Patents
1-substituted-2-4-(1-oxo-2-isoindolinyl)phenyl-propyl alcohol and their preparationInfo
- Publication number
- JPS5515401A JPS5515401A JP8670478A JP8670478A JPS5515401A JP S5515401 A JPS5515401 A JP S5515401A JP 8670478 A JP8670478 A JP 8670478A JP 8670478 A JP8670478 A JP 8670478A JP S5515401 A JPS5515401 A JP S5515401A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- isoindolinyl
- oxo
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:The title compound of formula I (X=amide, acylamide, carboxyl, alkoxycarbonyl, nitrile; R=H, acyl, tosyl).
EXAMPLE: 2-Hydroxy-3-[4-(1-oxo-2-isoindolinyl)phenyl]butanamide.
USE: Excellent antiphlogistic analgesic agent.
PROCESS: A compound of formula II (X1=amide, carboxyl, alkoxycarbonyl) is hydrogenated to give a compound of formula III, which is then acylated or tosylated into a compound of formula I. A metal catalyst, e.g. Pt, Ni, etc., is used in the catalytic reduction. An acylating agent, e.g. acetyl chloride, or a tosylating agnet, e.g. tosyl chloride, is used in the acylatiob, etc. of the compound III.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8670478A JPS5515401A (en) | 1978-07-18 | 1978-07-18 | 1-substituted-2-4-(1-oxo-2-isoindolinyl)phenyl-propyl alcohol and their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8670478A JPS5515401A (en) | 1978-07-18 | 1978-07-18 | 1-substituted-2-4-(1-oxo-2-isoindolinyl)phenyl-propyl alcohol and their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5515401A true JPS5515401A (en) | 1980-02-02 |
Family
ID=13894312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8670478A Pending JPS5515401A (en) | 1978-07-18 | 1978-07-18 | 1-substituted-2-4-(1-oxo-2-isoindolinyl)phenyl-propyl alcohol and their preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5515401A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5548260A (en) * | 1992-05-06 | 1996-08-20 | Mitsuba Electric Manufacturing Co., Ltd. | Contact assembly for a magnetic switch |
-
1978
- 1978-07-18 JP JP8670478A patent/JPS5515401A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5548260A (en) * | 1992-05-06 | 1996-08-20 | Mitsuba Electric Manufacturing Co., Ltd. | Contact assembly for a magnetic switch |
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