JPS55145664A - Dihydroindole derivative - Google Patents
Dihydroindole derivativeInfo
- Publication number
- JPS55145664A JPS55145664A JP5261079A JP5261079A JPS55145664A JP S55145664 A JPS55145664 A JP S55145664A JP 5261079 A JP5261079 A JP 5261079A JP 5261079 A JP5261079 A JP 5261079A JP S55145664 A JPS55145664 A JP S55145664A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- aralkyl
- dihydroindole
- derivative
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
NEW MATERIAL:A dihydroindole derivative of formula I or its salt [Q is 1W3C alkylene; R1 is H, lower alkyl, aralkyl, or acyl; R2 is H, aralkyl, acyl, (un)saturated lower alkylthio, or a group obtained by eliminating R2 from formula I; R3 is H, lower alkyl, aralkyl, acyloxy-lower-alkyl, or phthalimido-lower alkyl].
EXAMPLE: ( 2S )-1-( S-Benzoyl-3-mercaptopropanoyl-5, 6-diacetoxy-2, 3-dihydroindole-2-carboxylic acid methyl ester.
USE: Hypotensor which inhibits angiotensin-converting enzyme.
PROCESS: The objective compound of formula III is prepared, e.g. by reacting a compound of formula II (R4 is the group obtained by eliminating H from R1) with a ractive derivative of compound of formula R5S-Q-COOH (R5 is the same as R4).
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5261079A JPS55145664A (en) | 1979-04-28 | 1979-04-28 | Dihydroindole derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5261079A JPS55145664A (en) | 1979-04-28 | 1979-04-28 | Dihydroindole derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55145664A true JPS55145664A (en) | 1980-11-13 |
JPS6247180B2 JPS6247180B2 (en) | 1987-10-06 |
Family
ID=12919558
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5261079A Granted JPS55145664A (en) | 1979-04-28 | 1979-04-28 | Dihydroindole derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55145664A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4396773A (en) * | 1980-07-01 | 1983-08-02 | American Home Products Corporation | 1,1'-[Dithiobis(2-alkyl-1-oxo-3,1-propanediyl)]-bis[2,3-dihydro-1H-indole-2-carboxylic acids and derivatives |
-
1979
- 1979-04-28 JP JP5261079A patent/JPS55145664A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4396773A (en) * | 1980-07-01 | 1983-08-02 | American Home Products Corporation | 1,1'-[Dithiobis(2-alkyl-1-oxo-3,1-propanediyl)]-bis[2,3-dihydro-1H-indole-2-carboxylic acids and derivatives |
Also Published As
Publication number | Publication date |
---|---|
JPS6247180B2 (en) | 1987-10-06 |
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