JPS55143980A - Anti-allergic preparation - Google Patents
Anti-allergic preparationInfo
- Publication number
- JPS55143980A JPS55143980A JP5242579A JP5242579A JPS55143980A JP S55143980 A JPS55143980 A JP S55143980A JP 5242579 A JP5242579 A JP 5242579A JP 5242579 A JP5242579 A JP 5242579A JP S55143980 A JPS55143980 A JP S55143980A
- Authority
- JP
- Japan
- Prior art keywords
- allergic
- alkyl
- novel
- compounds
- acid addition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003266 anti-allergic effect Effects 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 3
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 208000026935 allergic disease Diseases 0.000 abstract 2
- 230000000172 allergic effect Effects 0.000 abstract 2
- 230000007815 allergy Effects 0.000 abstract 2
- 208000010668 atopic eczema Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- 150000003413 spiro compounds Chemical class 0.000 abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 108010074506 Transfer Factor Proteins 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 229960001340 histamine Drugs 0.000 abstract 1
- 210000003630 histaminocyte Anatomy 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5242579A JPS55143980A (en) | 1979-04-27 | 1979-04-27 | Anti-allergic preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5242579A JPS55143980A (en) | 1979-04-27 | 1979-04-27 | Anti-allergic preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55143980A true JPS55143980A (en) | 1980-11-10 |
| JPS6363533B2 JPS6363533B2 (enrdf_load_stackoverflow) | 1988-12-07 |
Family
ID=12914420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5242579A Granted JPS55143980A (en) | 1979-04-27 | 1979-04-27 | Anti-allergic preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55143980A (enrdf_load_stackoverflow) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894374A (en) * | 1988-08-17 | 1990-01-16 | American Home Products Corporation | Substituted 1,2-dihydro-4h-3,1-benzoxazin-4-one derivatives inhibitors of interleukin 1 |
| JPH04217960A (ja) * | 1989-12-08 | 1992-08-07 | Merck & Co Inc | 窒素含有スピロサイクル |
| WO1995028389A1 (fr) * | 1994-04-15 | 1995-10-26 | Yamanouchi Pharmaceutical Co., Ltd. | Compose spiro et composition medicinale issue de ce compose |
| US5658921A (en) * | 1992-06-12 | 1997-08-19 | H. Lundbeck A/S | Dimeric piperidine, tetrahydropyridine and piperazine derivatives |
| US5665725A (en) * | 1991-06-13 | 1997-09-09 | H. Lundbeck | Piperidine derivatives having anxiolytic effect |
| WO1997037630A3 (en) * | 1996-04-10 | 1998-01-29 | Richter Gedeon Vegyeszet | Spiro(2h-1-benzopyran-2,4'-piperidine)-4(3h)-one derivatives, acid addition salts thereof and pharmaceutical compositions containing them |
| WO2002048152A3 (en) * | 2000-12-12 | 2003-05-08 | Neurogen Corp | Spiro[isobenzofuran-1,4'-piperidin]-3-ones and 3h-spiroisobenzofuran-1,4'-piperidines |
| WO2003095427A1 (fr) * | 2002-05-10 | 2003-11-20 | Taisho Pharmaceutical Co.,Ltd. | Compose a noyau spiranique |
| WO2004035581A1 (ja) * | 2002-10-18 | 2004-04-29 | Ono Pharmaceutical Co., Ltd. | スピロ複素環誘導体化合物およびその化合物を有効成分とする薬剤 |
| EP1695977A3 (en) * | 2000-12-12 | 2006-09-20 | Neurogen Corporation | Spiro [isobenzofuran-1,4'piperidin]-3-ones and 3H-spiroisobenzofuran-1, 4'-piperidines |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63215820A (ja) * | 1987-03-02 | 1988-09-08 | Mazda Motor Corp | 直噴デイ−ゼルエンジン |
-
1979
- 1979-04-27 JP JP5242579A patent/JPS55143980A/ja active Granted
Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894374A (en) * | 1988-08-17 | 1990-01-16 | American Home Products Corporation | Substituted 1,2-dihydro-4h-3,1-benzoxazin-4-one derivatives inhibitors of interleukin 1 |
| JPH04217960A (ja) * | 1989-12-08 | 1992-08-07 | Merck & Co Inc | 窒素含有スピロサイクル |
| US5807871A (en) * | 1991-06-13 | 1998-09-15 | H. Lundbeck A/S | Piperidine derivatives having anxiolytic effect |
| US6031099A (en) * | 1991-06-13 | 2000-02-29 | H. Lundbeck A/S | Piperidine derivates having anxiolytic effect |
| US5665725A (en) * | 1991-06-13 | 1997-09-09 | H. Lundbeck | Piperidine derivatives having anxiolytic effect |
| US6207677B1 (en) | 1991-06-13 | 2001-03-27 | H. Lundbeck A/S | Piperidine derivatives having anxiolytic effect |
| EP0853085A1 (en) * | 1991-06-13 | 1998-07-15 | H. Lundbeck A/S | Piperidine derivatives having anxiolytic effect |
| US5830896A (en) * | 1992-06-12 | 1998-11-03 | H. Lundbeck A/S | Dimeric piperidine, tetrahydropyridine and piperazine derivatives |
| US5837707A (en) * | 1992-06-12 | 1998-11-17 | H. Lundbeck A/S | Dimeric piperidine, tetrahydropyridine and piperazine derivatives |
| US5658921A (en) * | 1992-06-12 | 1997-08-19 | H. Lundbeck A/S | Dimeric piperidine, tetrahydropyridine and piperazine derivatives |
| US6090808A (en) * | 1992-06-12 | 2000-07-18 | H. Lundbeck A/S | Dimeric piperidine, tetrahydropyridine and piperazine derivatives |
| US5684012A (en) * | 1992-06-12 | 1997-11-04 | H. Lundbeck A/S | Dimeric piperidine, tetrahydropyridine and piperazine derivatives |
| WO1995028389A1 (fr) * | 1994-04-15 | 1995-10-26 | Yamanouchi Pharmaceutical Co., Ltd. | Compose spiro et composition medicinale issue de ce compose |
| WO1997037630A3 (en) * | 1996-04-10 | 1998-01-29 | Richter Gedeon Vegyeszet | Spiro(2h-1-benzopyran-2,4'-piperidine)-4(3h)-one derivatives, acid addition salts thereof and pharmaceutical compositions containing them |
| WO2002048152A3 (en) * | 2000-12-12 | 2003-05-08 | Neurogen Corp | Spiro[isobenzofuran-1,4'-piperidin]-3-ones and 3h-spiroisobenzofuran-1,4'-piperidines |
| US6943199B2 (en) | 2000-12-12 | 2005-09-13 | Neurogen Corporation | Spiro[isobenzofuran-1,4′-piperidin]-3-ones and 3H-spiroisobenzofuran-1,4′-piperidines |
| EP1695977A3 (en) * | 2000-12-12 | 2006-09-20 | Neurogen Corporation | Spiro [isobenzofuran-1,4'piperidin]-3-ones and 3H-spiroisobenzofuran-1, 4'-piperidines |
| WO2003095427A1 (fr) * | 2002-05-10 | 2003-11-20 | Taisho Pharmaceutical Co.,Ltd. | Compose a noyau spiranique |
| WO2004035581A1 (ja) * | 2002-10-18 | 2004-04-29 | Ono Pharmaceutical Co., Ltd. | スピロ複素環誘導体化合物およびその化合物を有効成分とする薬剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6363533B2 (enrdf_load_stackoverflow) | 1988-12-07 |
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