JPS5513213A - 2-(9-beta-d-ribofuranosyl purin-6-yl)-3-aminoacrylonitrile and its preparation - Google Patents
2-(9-beta-d-ribofuranosyl purin-6-yl)-3-aminoacrylonitrile and its preparationInfo
- Publication number
- JPS5513213A JPS5513213A JP8519178A JP8519178A JPS5513213A JP S5513213 A JPS5513213 A JP S5513213A JP 8519178 A JP8519178 A JP 8519178A JP 8519178 A JP8519178 A JP 8519178A JP S5513213 A JPS5513213 A JP S5513213A
- Authority
- JP
- Japan
- Prior art keywords
- ribofuranosyl
- purin
- formula
- aminoacrylonitrile
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:2-(9-β-D-ribofuranosyl purin-6-yl)-3-aminoacrylonitrile shown by the formula I (R is H or protective group).
USE: Medicines and biochemical study reagents having antiallergy, antitumorigenic properties, and powerful dilation action of terminal flood vessel.
PROCESS: 2-(9-β-D-ribofuranosyl purin-6-yl)-2-cyanoacetonitrile shown by the for the formula II is subjected to catalytic reduction in the presence of a catalyst to give the desired compound shown by the formula I. For example, a raw material of the compound shown by the formula II is obtained by reacting a 9-D-ribofuranosyl- 6-chloropurine with malonomitrile in the presence of a fase in a reaction solvent.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8519178A JPS5513213A (en) | 1978-07-14 | 1978-07-14 | 2-(9-beta-d-ribofuranosyl purin-6-yl)-3-aminoacrylonitrile and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8519178A JPS5513213A (en) | 1978-07-14 | 1978-07-14 | 2-(9-beta-d-ribofuranosyl purin-6-yl)-3-aminoacrylonitrile and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5513213A true JPS5513213A (en) | 1980-01-30 |
JPS5710113B2 JPS5710113B2 (en) | 1982-02-24 |
Family
ID=13851753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8519178A Granted JPS5513213A (en) | 1978-07-14 | 1978-07-14 | 2-(9-beta-d-ribofuranosyl purin-6-yl)-3-aminoacrylonitrile and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5513213A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008180007A (en) * | 2007-01-25 | 2008-08-07 | Metropolitan Expressway Co Ltd | Concrete material feeder for use in concrete pavement |
-
1978
- 1978-07-14 JP JP8519178A patent/JPS5513213A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008180007A (en) * | 2007-01-25 | 2008-08-07 | Metropolitan Expressway Co Ltd | Concrete material feeder for use in concrete pavement |
Also Published As
Publication number | Publication date |
---|---|
JPS5710113B2 (en) | 1982-02-24 |
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