JPS5498789A - Preparation of pyrazinecarboxylic amide - Google Patents

Preparation of pyrazinecarboxylic amide

Info

Publication number
JPS5498789A
JPS5498789A JP217878A JP217878A JPS5498789A JP S5498789 A JPS5498789 A JP S5498789A JP 217878 A JP217878 A JP 217878A JP 217878 A JP217878 A JP 217878A JP S5498789 A JPS5498789 A JP S5498789A
Authority
JP
Japan
Prior art keywords
amide
pyrazinecarboxylic
pyrazine
persulfate
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP217878A
Other languages
Japanese (ja)
Inventor
Masao Kawamura
Masakazu Hatta
Morio Nakamura
Nobuhiro Koune
Yoshiaki Iwasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Seika Chemicals Co Ltd
Original Assignee
Seitetsu Kagaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seitetsu Kagaku Co Ltd filed Critical Seitetsu Kagaku Co Ltd
Priority to JP217878A priority Critical patent/JPS5498789A/en
Publication of JPS5498789A publication Critical patent/JPS5498789A/en
Pending legal-status Critical Current

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  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PURPOSE: To obtain a pyrazinecarboxylic amide useful as tuberculostatics in a simple process industrially advantageously, by reacting pyrazine with formamide and a persulfate to introduce an amide group into the pyrazine directly.
CONSTITUTION: One mole of pyrazine or its sulfate is mixed with 4W50 moles of formamide, and 0.2W2 moles of a persulfate, e.g. potassium or sodium persulfate, is added slowly and reacted with the mixture at 50W100°C. The reaction mixture is then vacuum distilled and extracted with CH3OH or CHCl3 to give pyrazinecarboxylic amide.
COPYRIGHT: (C)1979,JPO&Japio
JP217878A 1978-01-11 1978-01-11 Preparation of pyrazinecarboxylic amide Pending JPS5498789A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP217878A JPS5498789A (en) 1978-01-11 1978-01-11 Preparation of pyrazinecarboxylic amide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP217878A JPS5498789A (en) 1978-01-11 1978-01-11 Preparation of pyrazinecarboxylic amide

Publications (1)

Publication Number Publication Date
JPS5498789A true JPS5498789A (en) 1979-08-03

Family

ID=11522098

Family Applications (1)

Application Number Title Priority Date Filing Date
JP217878A Pending JPS5498789A (en) 1978-01-11 1978-01-11 Preparation of pyrazinecarboxylic amide

Country Status (1)

Country Link
JP (1) JPS5498789A (en)

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