JPS5495561A - Acylated pyrrole derivative and its preparation - Google Patents

Acylated pyrrole derivative and its preparation

Info

Publication number
JPS5495561A
JPS5495561A JP80178A JP80178A JPS5495561A JP S5495561 A JPS5495561 A JP S5495561A JP 80178 A JP80178 A JP 80178A JP 80178 A JP80178 A JP 80178A JP S5495561 A JPS5495561 A JP S5495561A
Authority
JP
Japan
Prior art keywords
formula
preparation
acylated
acyl
pyrrole derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP80178A
Other languages
Japanese (ja)
Inventor
Toshio Tanaka
Toshio Wakabayashi
Akira Otsu
Seiji Kurozumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP80178A priority Critical patent/JPS5495561A/en
Priority to US05/966,050 priority patent/US4233309A/en
Priority to EP78300757A priority patent/EP0002392A3/en
Publication of JPS5495561A publication Critical patent/JPS5495561A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:Acylated pyrrole derivatives of formula I (R1 is lower alkyl; R2 is H or lower alkyl; R3 is H or 2 - 10C acyl; Ar is 5 or 6 membered monoaromatic ring).
EXAMPLE: 2-]3-Benzoyl-2,5-dimethylpyrrole-1]-1-propanol.
USE: Analgesics, antiflammatory agents, antithrombotic agents, and antiarteriosclerosis.
PREPARATION: The condensation reaction of a pyrrole derivative of formula II (R31 is H or 2 - 10C acyl) with an acylating agent selected from the groups consisting of aromatic carboxylic acids, acid halides and anhydrides is effected in the presence of an acidic catalyst as sulfuric or Lewis acid, when necessary, followed by hydrolysis to prepare an acylated pyrrole of formula I.
COPYRIGHT: (C)1979,JPO&Japio
JP80178A 1977-12-06 1978-01-10 Acylated pyrrole derivative and its preparation Pending JPS5495561A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP80178A JPS5495561A (en) 1978-01-10 1978-01-10 Acylated pyrrole derivative and its preparation
US05/966,050 US4233309A (en) 1977-12-06 1978-12-04 Novel 1-substituted-3-acylpyrrole derivatives, platelet aggregation inhibitors containing them, as active ingredients, and processes for production of said derivatives
EP78300757A EP0002392A3 (en) 1977-12-06 1978-12-06 1-substituted-3-acylpyrrole derivatives, process for their preparation and platelet aggregation inhibiting agents containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP80178A JPS5495561A (en) 1978-01-10 1978-01-10 Acylated pyrrole derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5495561A true JPS5495561A (en) 1979-07-28

Family

ID=11483779

Family Applications (1)

Application Number Title Priority Date Filing Date
JP80178A Pending JPS5495561A (en) 1977-12-06 1978-01-10 Acylated pyrrole derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5495561A (en)

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