JPS54160371A - Novel piperidine derivative and hypotensive agents comprising it - Google Patents

Novel piperidine derivative and hypotensive agents comprising it

Info

Publication number
JPS54160371A
JPS54160371A JP6654878A JP6654878A JPS54160371A JP S54160371 A JPS54160371 A JP S54160371A JP 6654878 A JP6654878 A JP 6654878A JP 6654878 A JP6654878 A JP 6654878A JP S54160371 A JPS54160371 A JP S54160371A
Authority
JP
Japan
Prior art keywords
formula
group
compound
piperidine derivative
hypotensive agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6654878A
Other languages
English (en)
Inventor
Yoshihiro Nakamizo
Hiroyuki Obase
Kazuhiro Kubo
Yutaka Kasuya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP6654878A priority Critical patent/JPS54160371A/ja
Priority to IT68190/79A priority patent/IT1120985B/it
Priority to US06/191,339 priority patent/US4446141A/en
Priority to PCT/JP1979/000141 priority patent/WO1980000024A1/ja
Priority to DE7979900598T priority patent/DE2963225D1/de
Publication of JPS54160371A publication Critical patent/JPS54160371A/ja
Priority to EP79900598A priority patent/EP0018417B1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP6654878A 1978-06-02 1978-06-02 Novel piperidine derivative and hypotensive agents comprising it Pending JPS54160371A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP6654878A JPS54160371A (en) 1978-06-02 1978-06-02 Novel piperidine derivative and hypotensive agents comprising it
IT68190/79A IT1120985B (it) 1978-06-02 1979-06-01 Derivati della piperidina e procedimento per la loro preparazione
US06/191,339 US4446141A (en) 1978-06-02 1979-06-01 Hypotensive piperidine derivatives
PCT/JP1979/000141 WO1980000024A1 (en) 1978-06-02 1979-06-01 Novel piperidine derivatives
DE7979900598T DE2963225D1 (en) 1978-06-02 1979-06-01 Novel piperidine derivatives and pharmaceutical compositions containing them
EP79900598A EP0018417B1 (en) 1978-06-02 1980-01-14 Novel piperidine derivatives and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6654878A JPS54160371A (en) 1978-06-02 1978-06-02 Novel piperidine derivative and hypotensive agents comprising it

Publications (1)

Publication Number Publication Date
JPS54160371A true JPS54160371A (en) 1979-12-19

Family

ID=13319062

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6654878A Pending JPS54160371A (en) 1978-06-02 1978-06-02 Novel piperidine derivative and hypotensive agents comprising it

Country Status (6)

Country Link
US (1) US4446141A (ja)
EP (1) EP0018417B1 (ja)
JP (1) JPS54160371A (ja)
DE (1) DE2963225D1 (ja)
IT (1) IT1120985B (ja)
WO (1) WO1980000024A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5517385A (en) * 1978-07-20 1980-02-06 Science Union & Cie Benzimidazolinone derivative and medical composition containing it
JPS5668680A (en) * 1979-11-06 1981-06-09 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and hypotensive agent containing the same

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2469411A1 (fr) * 1979-11-15 1981-05-22 Science Union & Cie Nouveaux derives de la piperidylbenzimidazolinone, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
JPS5815979A (ja) * 1981-07-11 1983-01-29 Kyowa Hakko Kogyo Co Ltd 新規なピペリジン誘導体およびその製造法
DE3685382D1 (de) * 1985-08-27 1992-06-25 Ciba Geigy Ag Hydropyridin-derivate.
US4679258A (en) * 1985-11-12 1987-07-14 Henkin Melvyn Lane Hydrotherapy massage method and apparatus
US4957928A (en) * 1986-06-26 1990-09-18 Ciba-Geigy Corporation Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL135941C (ja) * 1961-12-22
US3318900A (en) * 1964-05-06 1967-05-09 Janssen Pharmaceutica Nv Derivatives of benzimidazolinyl piperidine
BE794333A (fr) * 1972-01-20 1973-07-19 Wyeth John & Brother Ltd Composes heterocycliques azotes therapeutiques
JPS595589B2 (ja) * 1972-04-12 1984-02-06 帝国化学産業 （株） アロイルアルキルビペリジン誘導体の製造法
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) * 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
JPS5417747B2 (ja) * 1973-11-30 1979-07-02
US4048058A (en) * 1975-08-13 1977-09-13 Standard Oil Company (Indiana) Methods to be used in reforming processes employing multi-metallic catalysts
JPS5227775A (en) * 1975-08-28 1977-03-02 Sumitomo Chem Co Ltd Preparation of novel acylhydrazone derivatives and their salts
GR69650B (ja) * 1978-07-20 1982-07-07 Science Union & Cie
US4264613A (en) * 1979-08-01 1981-04-28 Science Union Et Cie, Societe Francaise De Recherche Medicale Piperidylbenzimidazolinone compounds
JPS5924990B2 (ja) * 1979-11-21 1984-06-13 協和醗酵工業株式会社 新規なピペリジン誘導体

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5517385A (en) * 1978-07-20 1980-02-06 Science Union & Cie Benzimidazolinone derivative and medical composition containing it
JPS5668680A (en) * 1979-11-06 1981-06-09 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and hypotensive agent containing the same

Also Published As

Publication number Publication date
IT1120985B (it) 1986-03-26
IT7968190A0 (it) 1979-06-01
US4446141A (en) 1984-05-01
EP0018417B1 (en) 1982-06-30
EP0018417A4 (en) 1980-05-06
DE2963225D1 (en) 1982-08-19
WO1980000024A1 (en) 1980-01-10
EP0018417A1 (en) 1980-11-12

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