JPS54157566A - Preparation of nucleoside - Google Patents

Preparation of nucleoside

Info

Publication number
JPS54157566A
JPS54157566A JP6640678A JP6640678A JPS54157566A JP S54157566 A JPS54157566 A JP S54157566A JP 6640678 A JP6640678 A JP 6640678A JP 6640678 A JP6640678 A JP 6640678A JP S54157566 A JPS54157566 A JP S54157566A
Authority
JP
Japan
Prior art keywords
nucleoside
sugar
reacted
benzoxazolium
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6640678A
Other languages
Japanese (ja)
Other versions
JPS6244557B2 (en
Inventor
Mitsuaki Mukoyama
Shinichiro Shoda
Takashi Nakatsuka
Koichi Narasaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP6640678A priority Critical patent/JPS54157566A/en
Publication of JPS54157566A publication Critical patent/JPS54157566A/en
Publication of JPS6244557B2 publication Critical patent/JPS6244557B2/ja
Granted legal-status Critical Current

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Abstract

PURPOSE: To prepare nucleoside useful as medicines, pesticides, or their intermediates, in high yield under mild conditions of reaction temperature, etc. without using heavy metal or acid catalysts, by using a benzoxazolium salt.
CONSTITUTION: A benzoxazolium salt, e.g. 3-ethyl-2-chlorobenzoxazolium tetrafluroborate, is reacted with a nucleoside base, e.g. imidazole, in the presence of a tertiary amine, e.g. triethylamine, in an inert solvent at room temperature W 100°C. The reaction mixture is then treated with a triethyloxonium tetrafluoroborate to remove the remaining chloride ions, and sugar, e.g. 1-hydroxy-sugar, is reacted under the same reaction conditions as described above to form the objective nucleoside. The raw materials are used in amounts equimolar with the starting material.
COPYRIGHT: (C)1979,JPO&Japio
JP6640678A 1978-06-02 1978-06-02 Preparation of nucleoside Granted JPS54157566A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6640678A JPS54157566A (en) 1978-06-02 1978-06-02 Preparation of nucleoside

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6640678A JPS54157566A (en) 1978-06-02 1978-06-02 Preparation of nucleoside

Publications (2)

Publication Number Publication Date
JPS54157566A true JPS54157566A (en) 1979-12-12
JPS6244557B2 JPS6244557B2 (en) 1987-09-21

Family

ID=13314877

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6640678A Granted JPS54157566A (en) 1978-06-02 1978-06-02 Preparation of nucleoside

Country Status (1)

Country Link
JP (1) JPS54157566A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111961380A (en) * 2020-07-25 2020-11-20 候伟强 Household water-based paint and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111961380A (en) * 2020-07-25 2020-11-20 候伟强 Household water-based paint and preparation method thereof

Also Published As

Publication number Publication date
JPS6244557B2 (en) 1987-09-21

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