JPS54154763A - Thiazolidine derivative - Google Patents

Thiazolidine derivative

Info

Publication number
JPS54154763A
JPS54154763A JP6289478A JP6289478A JPS54154763A JP S54154763 A JPS54154763 A JP S54154763A JP 6289478 A JP6289478 A JP 6289478A JP 6289478 A JP6289478 A JP 6289478A JP S54154763 A JPS54154763 A JP S54154763A
Authority
JP
Japan
Prior art keywords
formula
compound
group
reacted
lower alkanoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6289478A
Other languages
Japanese (ja)
Inventor
Katsuo Arimura
Osamu Murakami
Taichi Oka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP6289478A priority Critical patent/JPS54154763A/en
Publication of JPS54154763A publication Critical patent/JPS54154763A/en
Pending legal-status Critical Current

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Landscapes

  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A thiazolidine derivative of formula I: (R1 is lower alkanoyl, alkoxycarbonyl, or N-alkyl-thiocarbamoyl group; R2 is H or CH3 group).
EXAMPLE: 3-[3-Acetylthio-2(S)-methylpropionyl]-4(R)-thiazolidinecarboxylic acid.
USE: Medicines, e.g. remedies for hypertension, having hypotensive actions.
PROCESS: A reactive derivative, e.g. an acid chloride, of a compound of formula II is reacted with a 4(R)-thiazolidinecarboxylic acid of formula III usually in the presence of an deacidification agent, e.g. triethylamine, in an inert solvent, e.g. methylene chloride, to give the objective compound of formula I. Alternatively, the compound of formula III is reacted with a compound of formula IV: (X is halogen; R1 is lower alkanoyl or alkoxycarbonyl group) or a compound of formula V: (R3 is a alkyl group).
COPYRIGHT: (C)1979,JPO&Japio
JP6289478A 1978-05-25 1978-05-25 Thiazolidine derivative Pending JPS54154763A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6289478A JPS54154763A (en) 1978-05-25 1978-05-25 Thiazolidine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6289478A JPS54154763A (en) 1978-05-25 1978-05-25 Thiazolidine derivative

Publications (1)

Publication Number Publication Date
JPS54154763A true JPS54154763A (en) 1979-12-06

Family

ID=13213401

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6289478A Pending JPS54154763A (en) 1978-05-25 1978-05-25 Thiazolidine derivative

Country Status (1)

Country Link
JP (1) JPS54154763A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981002893A1 (en) * 1980-04-02 1981-10-15 Santen Pharmaceutical Co Ltd Sulfur-containing acylamino acids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981002893A1 (en) * 1980-04-02 1981-10-15 Santen Pharmaceutical Co Ltd Sulfur-containing acylamino acids

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