JPS54148701A - Novel macrolide antibiotic, its preparaion and its producing bacteria - Google Patents

Novel macrolide antibiotic, its preparaion and its producing bacteria

Info

Publication number
JPS54148701A
JPS54148701A JP5437378A JP5437378A JPS54148701A JP S54148701 A JPS54148701 A JP S54148701A JP 5437378 A JP5437378 A JP 5437378A JP 5437378 A JP5437378 A JP 5437378A JP S54148701 A JPS54148701 A JP S54148701A
Authority
JP
Japan
Prior art keywords
macrolide antibiotic
ch3oh
alpha
preparaion
white powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5437378A
Other languages
Japanese (ja)
Other versions
JPS6121480B2 (en
Inventor
Masaru Kotani
Shuzo Satoi
Naoki Muto
Satoru Saito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Priority to JP5437378A priority Critical patent/JPS54148701A/en
Priority to CA326,416A priority patent/CA1125203A/en
Priority to GB7915807A priority patent/GB2020647B/en
Priority to NL7903601A priority patent/NL192621C/en
Priority to ES480405A priority patent/ES480405A1/en
Priority to DE19792918711 priority patent/DE2918711A1/en
Priority to DE2954218A priority patent/DE2954218C2/en
Priority to FR7911883A priority patent/FR2425444A1/en
Priority to IT22536/79A priority patent/IT1113372B/en
Priority to US06/037,846 priority patent/US4291021A/en
Publication of JPS54148701A publication Critical patent/JPS54148701A/en
Publication of JPS6121480B2 publication Critical patent/JPS6121480B2/ja
Granted legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

NEW MATERIAL:Antibiotics A11725I and A11725II, and their salts. Properties thereof are as follows. A11725I: white powder; molecular formula C37H61NO12; molecular weight 711; m.p. 103-107 deg.C; [alpha]D= -40.0 deg. (c=1, CH3OH); color reaction, discoloration of KMnO4 aqueous solution +, each of ninhydrin, Sakaguchi and ferric chloride reactions -; etc. A-11725II: white powder; molecular formula C37H61NO13; molecular weight 727; m.p. 102-106 deg.C; [alpha]D= -31.0 deg. (c=1, CH3OH); color reaction, the same as A11725I: etc. USE:Macrolide antibiotic which is especially effectibve against staphylococci and mycoplasma. PROCESS:Strains of micromonospora SPA11725 (FERM-P No.4488) are cultured under aerobic conditions in a medium containing assimilable C, N source and inorganic substances, to collect A11725Iand II from a cultured substance.
JP5437378A 1978-05-10 1978-05-10 Novel macrolide antibiotic, its preparaion and its producing bacteria Granted JPS54148701A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP5437378A JPS54148701A (en) 1978-05-10 1978-05-10 Novel macrolide antibiotic, its preparaion and its producing bacteria
CA326,416A CA1125203A (en) 1978-05-10 1979-04-26 Macrolide antibiotics from micromonospora
GB7915807A GB2020647B (en) 1978-05-10 1979-05-08 Macrolide antibiotics a 11725 1 2 and 3 preparation thereo
NL7903601A NL192621C (en) 1978-05-10 1979-05-08 Method for the preparation of new antibiotics, which belong to the macrolides, microorganisms of the strain Micromonospora, which are capable of producing these new antibiotics; and new antibiotics and pharmaceutical preparations.
ES480405A ES480405A1 (en) 1978-05-10 1979-05-09 Novel macrolide antibiotics and preparation thereof
DE19792918711 DE2918711A1 (en) 1978-05-10 1979-05-09 MACROLID ANTIBIOTICS, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE ANTIBIOTICS
DE2954218A DE2954218C2 (en) 1978-05-10 1979-05-09 Macrolide antibiotics and pharmaceutical preparations containing these antibiotics
FR7911883A FR2425444A1 (en) 1978-05-10 1979-05-10 NEW MACROLIDE-TYPE ANTIBIOTICS, THEIR PREPARATION AND THERAPEUTIC USE
IT22536/79A IT1113372B (en) 1978-05-10 1979-05-10 PROCEDURE TO PRODUCE ANTIBIOTIC SUBSTANCES AND THEIR ANTIBIOTICS SO OBTAINED
US06/037,846 US4291021A (en) 1978-05-10 1979-05-10 Novel macrolide antibiotics and preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5437378A JPS54148701A (en) 1978-05-10 1978-05-10 Novel macrolide antibiotic, its preparaion and its producing bacteria

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP60206347A Division JPS6192577A (en) 1985-09-20 1985-09-20 Novel macrolide antibiotic and its production
JP60206348A Division JPS6192564A (en) 1985-09-20 1985-09-20 Microorganism producing novel macrolide antibiotic

Publications (2)

Publication Number Publication Date
JPS54148701A true JPS54148701A (en) 1979-11-21
JPS6121480B2 JPS6121480B2 (en) 1986-05-27

Family

ID=12968859

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5437378A Granted JPS54148701A (en) 1978-05-10 1978-05-10 Novel macrolide antibiotic, its preparaion and its producing bacteria

Country Status (1)

Country Link
JP (1) JPS54148701A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5683497A (en) * 1979-11-09 1981-07-08 Schering Corp Macrolide antibiotic* its manufacture and medicinal composition containing it

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5683497A (en) * 1979-11-09 1981-07-08 Schering Corp Macrolide antibiotic* its manufacture and medicinal composition containing it

Also Published As

Publication number Publication date
JPS6121480B2 (en) 1986-05-27

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