JPS54148000A - Preparation of antibiotic substance - Google Patents

Preparation of antibiotic substance

Info

Publication number
JPS54148000A
JPS54148000A JP5424378A JP5424378A JPS54148000A JP S54148000 A JPS54148000 A JP S54148000A JP 5424378 A JP5424378 A JP 5424378A JP 5424378 A JP5424378 A JP 5424378A JP S54148000 A JPS54148000 A JP S54148000A
Authority
JP
Japan
Prior art keywords
cephamycin
streptomyces
inositovorus
chromatography
bacteria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5424378A
Other languages
Japanese (ja)
Other versions
JPS574237B2 (en
Inventor
Ichiro Takase
Masahiro Kamata
Yoshiteru Hirose
Saburo Yamagishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP5424378A priority Critical patent/JPS54148000A/en
Publication of JPS54148000A publication Critical patent/JPS54148000A/en
Publication of JPS574237B2 publication Critical patent/JPS574237B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To prepare cephamycin C useful as an antibiotic substance, economically, in an industrial scale, by culturing specific bacteria.
CONSTITUTION: Streptomyces inositovorus AJ9408 (FERM-P No.4482) which belongs to a novel species of Streptomyces genus, Streptomyces inositovorus, is aerobically cultured in a nutrient liquid medium at 13W33°C and pH3W9 for 26W 100 hours. The cultured liquid is filtered or centrifuged to separate the insoluble residue, and the objective cephamycin C is separated from the filtrate by adsorption chromatography, partition chromatography, ion exchange chromatography, gel filtration, etc. Cephamycin C having the structure of the formula, has strong antibacterial activity to Gram-negative bacteria, and is effective even to penicillin- resistant bacteria.
COPYRIGHT: (C)1979,JPO&Japio
JP5424378A 1978-05-08 1978-05-08 Preparation of antibiotic substance Granted JPS54148000A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5424378A JPS54148000A (en) 1978-05-08 1978-05-08 Preparation of antibiotic substance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5424378A JPS54148000A (en) 1978-05-08 1978-05-08 Preparation of antibiotic substance

Publications (2)

Publication Number Publication Date
JPS54148000A true JPS54148000A (en) 1979-11-19
JPS574237B2 JPS574237B2 (en) 1982-01-25

Family

ID=12965095

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5424378A Granted JPS54148000A (en) 1978-05-08 1978-05-08 Preparation of antibiotic substance

Country Status (1)

Country Link
JP (1) JPS54148000A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4942893A (en) * 1972-08-31 1974-04-22
JPS4945594A (en) * 1972-09-08 1974-05-01

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4942893A (en) * 1972-08-31 1974-04-22
JPS4945594A (en) * 1972-09-08 1974-05-01

Also Published As

Publication number Publication date
JPS574237B2 (en) 1982-01-25

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