JPS54148000A - Preparation of antibiotic substance - Google Patents
Preparation of antibiotic substanceInfo
- Publication number
- JPS54148000A JPS54148000A JP5424378A JP5424378A JPS54148000A JP S54148000 A JPS54148000 A JP S54148000A JP 5424378 A JP5424378 A JP 5424378A JP 5424378 A JP5424378 A JP 5424378A JP S54148000 A JPS54148000 A JP S54148000A
- Authority
- JP
- Japan
- Prior art keywords
- cephamycin
- streptomyces
- inositovorus
- chromatography
- bacteria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To prepare cephamycin C useful as an antibiotic substance, economically, in an industrial scale, by culturing specific bacteria.
CONSTITUTION: Streptomyces inositovorus AJ9408 (FERM-P No.4482) which belongs to a novel species of Streptomyces genus, Streptomyces inositovorus, is aerobically cultured in a nutrient liquid medium at 13W33°C and pH3W9 for 26W 100 hours. The cultured liquid is filtered or centrifuged to separate the insoluble residue, and the objective cephamycin C is separated from the filtrate by adsorption chromatography, partition chromatography, ion exchange chromatography, gel filtration, etc. Cephamycin C having the structure of the formula, has strong antibacterial activity to Gram-negative bacteria, and is effective even to penicillin- resistant bacteria.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5424378A JPS54148000A (en) | 1978-05-08 | 1978-05-08 | Preparation of antibiotic substance |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5424378A JPS54148000A (en) | 1978-05-08 | 1978-05-08 | Preparation of antibiotic substance |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54148000A true JPS54148000A (en) | 1979-11-19 |
JPS574237B2 JPS574237B2 (en) | 1982-01-25 |
Family
ID=12965095
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5424378A Granted JPS54148000A (en) | 1978-05-08 | 1978-05-08 | Preparation of antibiotic substance |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54148000A (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4942893A (en) * | 1972-08-31 | 1974-04-22 | ||
JPS4945594A (en) * | 1972-09-08 | 1974-05-01 |
-
1978
- 1978-05-08 JP JP5424378A patent/JPS54148000A/en active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4942893A (en) * | 1972-08-31 | 1974-04-22 | ||
JPS4945594A (en) * | 1972-09-08 | 1974-05-01 |
Also Published As
Publication number | Publication date |
---|---|
JPS574237B2 (en) | 1982-01-25 |
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