JPS54109975A - Thienohydantoin derivative - Google Patents
Thienohydantoin derivativeInfo
- Publication number
- JPS54109975A JPS54109975A JP444379A JP444379A JPS54109975A JP S54109975 A JPS54109975 A JP S54109975A JP 444379 A JP444379 A JP 444379A JP 444379 A JP444379 A JP 444379A JP S54109975 A JPS54109975 A JP S54109975A
- Authority
- JP
- Japan
- Prior art keywords
- thienohydantoin
- derivative
- thienohydantoin derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/870,542 US4127665A (en) | 1978-01-18 | 1978-01-18 | Thienohydantoin derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS54109975A true JPS54109975A (en) | 1979-08-29 |
| JPS612067B2 JPS612067B2 (US20090177143A1-20090709-C00008.png) | 1986-01-22 |
Family
ID=25355609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP444379A Granted JPS54109975A (en) | 1978-01-18 | 1979-01-17 | Thienohydantoin derivative |
Country Status (11)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018104454A (ja) * | 2009-12-04 | 2018-07-05 | サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． | 多環式化合物及びその使用方法 |
| US10815249B2 (en) | 2018-02-16 | 2020-10-27 | Sunovion Pharmaceuticals Inc. | Salts, crystal forms, and production methods thereof |
| US11129807B2 (en) | 2017-02-16 | 2021-09-28 | Sunovion Pharmaceuticals Inc. | Methods of treating schizophrenia |
| US11738002B2 (en) | 2020-04-14 | 2023-08-29 | Sunovion Pharmaceuticals Inc. | Methods of treating neurological and psychiatric disorders |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147797A (en) * | 1978-08-11 | 1979-04-03 | Pfizer Inc. | Spiro-furanohydantoin derivatives |
| US4181728A (en) * | 1978-11-16 | 1980-01-01 | Pfizer Inc. | Spiro-polycyclicimidazolidinedione derivatives |
| US4181729A (en) * | 1979-03-21 | 1980-01-01 | Pfizer Inc. | Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives |
| US4210667A (en) * | 1979-04-19 | 1980-07-01 | Pfizer Inc. | Pharmaceutical preparations containing coumarin carboxylic acid derivatives |
| AU532110B2 (en) * | 1979-11-13 | 1983-09-15 | Ici Ltd. | Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives |
| ATE10940T1 (de) * | 1981-05-12 | 1985-01-15 | Imperial Chemical Industries Plc | Pyrrolderivate. |
| US4540700A (en) * | 1982-04-15 | 1985-09-10 | Alcon Laboratories, Inc. | Treatment of diabetic complications with certain spiro-imidazolidine-diones |
| US4464385A (en) * | 1982-04-15 | 1984-08-07 | Alcon Laboratories, Inc. | Treatment of diabetic complications with hydantoins |
| US4436745A (en) | 1982-04-15 | 1984-03-13 | Alcon Laboratories, Inc. | Method of inhibiting aldose reductase activity |
| US4438272A (en) | 1982-04-15 | 1984-03-20 | Alcon Laboratories, Inc. | Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones |
| US5070100A (en) * | 1983-09-14 | 1991-12-03 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives |
| US4864028A (en) * | 1983-09-14 | 1989-09-05 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives |
| US4537892A (en) * | 1983-09-14 | 1985-08-27 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase |
| US5153211A (en) * | 1983-09-14 | 1992-10-06 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase |
| US4680306A (en) * | 1984-07-20 | 1987-07-14 | Pfizer Inc. | Sprio-imidazolones for treatment of diabetes complications |
| US4966911A (en) * | 1984-11-20 | 1990-10-30 | Washington Research Foundation | Immunoregulatory agents |
| US5340829A (en) * | 1984-11-20 | 1994-08-23 | Washington Research Foundation | Immunoregulatory agents |
| JP2708507B2 (ja) * | 1988-04-07 | 1998-02-04 | 株式会社三和化学研究所 | （ｄ）‐６‐フルオロ‐２，３‐ジヒドロ‐２’，５’‐ジオキソ‐スピロ［４Ｈ‐１‐ベンゾピラン‐４，４’‐イミダゾリジン］‐２‐カルボキサミド誘導体、これらの製法及び用途 |
| EP0536119A4 (en) * | 1989-02-10 | 1993-08-04 | Washington Research Foundation | Immunoregulatory agents |
| KR20190065246A (ko) | 2016-07-29 | 2019-06-11 | 선오비온 파마슈티컬스 인코포레이티드 | 화합물 및 조성물 및 이들의 용도 |
| CN116283877A (zh) | 2016-07-29 | 2023-06-23 | 赛诺维信制药公司 | 化合物、组合物及其用途 |
| SG11202000669VA (en) | 2017-08-02 | 2020-02-27 | Sunovion Pharmaceuticals Inc | Isochroman compounds and uses thereof |
| AU2020236225A1 (en) | 2019-03-14 | 2021-09-16 | Sunovion Pharmaceuticals Inc. | Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB796069A (en) * | 1955-12-23 | 1958-06-04 | Ici Ltd | Substituted hydantoins |
| DE1135915B (de) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine |
| CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
-
1978
- 1978-01-18 US US05/870,542 patent/US4127665A/en not_active Expired - Lifetime
-
1979
- 1979-01-16 DE DE2901477A patent/DE2901477C2/de not_active Expired
- 1979-01-16 BE BE0/192915A patent/BE873500A/xx not_active IP Right Cessation
- 1979-01-16 LU LU80795A patent/LU80795A1/xx unknown
- 1979-01-17 JP JP444379A patent/JPS54109975A/ja active Granted
- 1979-01-17 FR FR7901155A patent/FR2415112A1/fr active Granted
- 1979-01-17 DK DK019579A patent/DK151260C/da not_active IP Right Cessation
- 1979-01-17 GB GB791692A patent/GB2012759B/en not_active Expired
- 1979-01-17 NL NLAANVRAGE7900354,A patent/NL176459B/xx not_active IP Right Cessation
- 1979-01-17 IT IT19369/79A patent/IT1110007B/it active
- 1979-01-30 IE IE88/79A patent/IE47726B1/en unknown
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018104454A (ja) * | 2009-12-04 | 2018-07-05 | サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． | 多環式化合物及びその使用方法 |
| US10894033B2 (en) | 2009-12-04 | 2021-01-19 | Sunovion Pharmaceuticals Inc. | Multicyclic compounds and methods of use thereof |
| US11129807B2 (en) | 2017-02-16 | 2021-09-28 | Sunovion Pharmaceuticals Inc. | Methods of treating schizophrenia |
| US10815249B2 (en) | 2018-02-16 | 2020-10-27 | Sunovion Pharmaceuticals Inc. | Salts, crystal forms, and production methods thereof |
| US11440921B2 (en) | 2018-02-16 | 2022-09-13 | Sunovion Pharmaceuticals Inc. | Salts, crystal forms, and production methods thereof |
| US11738002B2 (en) | 2020-04-14 | 2023-08-29 | Sunovion Pharmaceuticals Inc. | Methods of treating neurological and psychiatric disorders |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7900354A (nl) | 1979-07-20 |
| IT1110007B (it) | 1985-12-23 |
| DK151260B (da) | 1987-11-16 |
| FR2415112B1 (US20090177143A1-20090709-C00008.png) | 1983-01-14 |
| DE2901477C2 (de) | 1982-06-09 |
| DK151260C (da) | 1988-05-09 |
| FR2415112A1 (fr) | 1979-08-17 |
| DE2901477A1 (de) | 1979-07-19 |
| BE873500A (fr) | 1979-07-16 |
| US4127665A (en) | 1978-11-28 |
| GB2012759B (en) | 1982-05-26 |
| LU80795A1 (fr) | 1979-09-07 |
| IE47726B1 (en) | 1984-05-30 |
| IE790088L (en) | 1979-07-18 |
| DK19579A (da) | 1979-07-19 |
| NL176459B (nl) | 1984-11-16 |
| IT7919369A0 (it) | 1979-01-17 |
| GB2012759A (en) | 1979-08-01 |
| JPS612067B2 (US20090177143A1-20090709-C00008.png) | 1986-01-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2033893B (en) | Tetrazolylalkoxycarbostyril derivatives | |
| JPS54109975A (en) | Thienohydantoin derivative | |
| JPS54141798A (en) | 44desacetyl vlboo33carboxyhydrazide derivative | |
| JPS54119450A (en) | 2hhbenzofurann33one derivative | |
| JPS5527193A (en) | Spiroofuranohydantoin derivative | |
| JPS54132627A (en) | Cumalin derivative | |
| GB2022079B (en) | L-leucyl-4-hydroxyanilide derivatives | |
| JPS54151966A (en) | Nnsubstituted oxobenzothiazoline derivative | |
| GB2018757B (en) | 3-phenyltetrahydropyridine derivatives | |
| PH17055A (en) | Delta4-androstenes derivative | |
| GB2036744B (en) | Eburnane derivatives | |
| GB2017708B (en) | Steroid-spirooxazolidinone derivatives | |
| JPS54128570A (en) | Arylaminoimidazoline derivative | |
| GB2019843B (en) | N-alkenylmoranoline derivatives | |
| GB2017691B (en) | 2-hydroxymethyl-pyrazine derivatives | |
| JPS5543080A (en) | 22oxazolin derivative | |
| GB2024806B (en) | Onomycin derivatives | |
| JPS54163596A (en) | Flonaphlizine derivative | |
| JPS54109991A (en) | 111alkanoyll4***deoxyy4***isonitroooleandomycin derivative | |
| GB2013187B (en) | Phenylpyrol derivatives | |
| GB2023574B (en) | N-cyano-azomethine derivatives | |
| JPS557262A (en) | Novel bettaine derivative | |
| JPS5581835A (en) | Novel pentenee22yl derivative | |
| JPS54151967A (en) | Nnsubstituted oxobenzothiazoline derivative | |
| JPS54154775A (en) | Benzylpyrimidine derivative |