JPS5387346A - Labelled bile acid - Google Patents

Labelled bile acid

Info

Publication number
JPS5387346A
JPS5387346A JP79378A JP79378A JPS5387346A JP S5387346 A JPS5387346 A JP S5387346A JP 79378 A JP79378 A JP 79378A JP 79378 A JP79378 A JP 79378A JP S5387346 A JPS5387346 A JP S5387346A
Authority
JP
Japan
Prior art keywords
bile acid
labelled
labelled bile
acid
bile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP79378A
Other languages
English (en)
Japanese (ja)
Inventor
Monkusu Rejinarudo
Reonaado Maaku Ririi Ansonii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
Radiochemical Centre Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Radiochemical Centre Ltd filed Critical Radiochemical Centre Ltd
Publication of JPS5387346A publication Critical patent/JPS5387346A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0493—Steroids, e.g. cholesterol, testosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP79378A 1977-01-07 1978-01-06 Labelled bile acid Pending JPS5387346A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB628/77A GB1592791A (en) 1977-01-07 1977-01-07 Selenium- or tellurium-containing bile acids and derivatives thereof

Publications (1)

Publication Number Publication Date
JPS5387346A true JPS5387346A (en) 1978-08-01

Family

ID=9707693

Family Applications (2)

Application Number Title Priority Date Filing Date
JP79378A Pending JPS5387346A (en) 1977-01-07 1978-01-06 Labelled bile acid
JP53000794A Expired JPS587612B2 (ja) 1977-01-07 1978-01-06 体機能調査剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP53000794A Expired JPS587612B2 (ja) 1977-01-07 1978-01-06 体機能調査剤

Country Status (5)

Country Link
US (2) US4202876A (cg-RX-API-DMAC7.html)
JP (2) JPS5387346A (cg-RX-API-DMAC7.html)
DE (2) DE2800780A1 (cg-RX-API-DMAC7.html)
FR (1) FR2376868A1 (cg-RX-API-DMAC7.html)
GB (1) GB1592791A (cg-RX-API-DMAC7.html)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7801908A (nl) * 1978-02-21 1979-08-23 Philips Nv Selenomethionine-75se bevattende oplossing, voor- zien van een thiol als stabilisator.
GB2028333B (en) * 1978-07-03 1982-10-27 Radiochemical Centre Ltd Selenium and tellurium derivatives of bile acids
US4363793A (en) * 1979-08-30 1982-12-14 State University Of New York Diagnostic radiopharmaceuticals for localization in target tissues exhibiting a regional pH shift relative to surrounding tissues
US4848349A (en) * 1987-04-29 1989-07-18 Sherman Igor A Substance and method for measuring hepatic blood flow
US5079240A (en) * 1990-03-15 1992-01-07 The Regents Of The University Of California Synthetic conjugated bile acid and method of use thereof
US5571783A (en) * 1993-03-09 1996-11-05 Clintec Nutrition Company Composition and method for treating patients with hepatic disease
US5506147A (en) * 1993-04-15 1996-04-09 Kolhouse; J. Fred Non-invasive evaluation of maldigestion and malaborption
US5602236A (en) * 1994-04-08 1997-02-11 Mallinckrodt Medical, Inc. Metal-containing steroid mimics and ligands useful in the preparation thereof
EP1023314B1 (en) * 1997-10-09 2003-02-12 Ice s.r.l. Bile acid salts of metals with physiological action and the use thereof in therapy
US20050183190A1 (en) * 2002-03-15 2005-08-25 Hussey Patrick P. Goggle contoured for helmet engagement
US20050193478A1 (en) * 2003-10-27 2005-09-08 Hussey Patrick P. Goggle attachment system
PL2724345T3 (pl) 2011-06-23 2019-03-29 Source Production & Equipment Co., Inc. Sposób wytwarzania źródła promieniowania gamma
CA2966885A1 (en) 2014-11-06 2016-05-12 Enanta Pharmaceuticals, Inc. Bile acid analogs an fxr/tgr5 agonists and methods of use thereof
US10208081B2 (en) 2014-11-26 2019-02-19 Enanta Pharmaceuticals, Inc. Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof
US10519191B2 (en) 2014-11-26 2019-12-31 Enanta Pharmaceuticals, Inc. Bile acid analogs as FXR/TGR5 agonists and methods of use thereof
WO2016086115A1 (en) 2014-11-26 2016-06-02 Enanta Pharmaceuticals, Inc. Tetrazole derivatives of bile acids as fxr/tgr5 agonists and methods of use thereof
KR20170133339A (ko) 2015-02-11 2017-12-05 이난타 파마슈티칼스, 인코포레이티드 Fxr/tgr5 작용제로서의 담즙산 유사체 및 이의 이용 방법
PL3277286T3 (pl) 2015-03-31 2021-11-08 Enanta Pharmaceuticals, Inc. Pochodne kwasu żółciowego jako agonisty fxr/tgr5 i sposoby ich stosowania
US10364267B2 (en) 2016-02-23 2019-07-30 Enanta Pharmaceuticals, Inc. Deuterated bile acid derivatives as FXR/TGR5 agonists and methods of use thereof
US10323061B2 (en) 2016-02-23 2019-06-18 Enanta Pharmaceuticals, Inc. Heteroaryl containing bile acid analogs as FXR/TGR5 agonists and methods of use thereof
WO2017147137A1 (en) 2016-02-23 2017-08-31 Enanta Pharmaceuticals, Inc. Benzoic acid derivatives of bile acid as fxr/tgr5 agonists and methods of use thereof
ES2918698T3 (es) 2016-11-29 2022-07-19 Enanta Pharm Inc Proceso para la preparación de derivados del ácido biliar de las sulfonilureas
US10472386B2 (en) 2017-02-14 2019-11-12 Enanta Pharmaceuticals, Inc. Bile acid derivatives as FXR agonists and methods of use thereof
WO2018187804A1 (en) 2017-04-07 2018-10-11 Enanta Pharmaceuticals, Inc. Process for preparation of sulfonyl carbamate bile acid derivatives
CN115260272A (zh) * 2022-08-17 2022-11-01 南宁师范大学 胆固醇硒氰酸酯类化合物及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3784576A (en) * 1970-09-24 1974-01-08 Univ Michigan Halogenated cholesterol
DK290774A (cg-RX-API-DMAC7.html) * 1973-06-08 1975-02-03 Schering Ag
NL7315287A (nl) * 1973-11-08 1975-05-12 Philips Nv Methode voor de bepaling van vetresorptie als- mede hierbij toegepaste stoffen en daarvan af- geleide preparaten.
GB1458267A (en) * 1974-02-20 1976-12-15 Radiochemical Centre Ltd Selentium-containing steroids and their use in organ visualisation
NL7415526A (nl) * 1974-11-28 1976-06-01 Tno Selenyl- en telluryl derivaten van steroiden, alsmede toepassing van deze verbindingen in diagnostische preparaten.
GB1550832A (en) * 1975-07-02 1979-08-22 Radiochemical Centre Ltd Selenium-containing steroids and their use in organ visualisation
GB2028333B (en) * 1978-07-03 1982-10-27 Radiochemical Centre Ltd Selenium and tellurium derivatives of bile acids

Also Published As

Publication number Publication date
DE2800781C2 (de) 1983-06-30
US4172085A (en) 1979-10-23
GB1592791A (en) 1981-07-08
DE2800780A1 (de) 1978-07-13
US4202876A (en) 1980-05-13
FR2376868A1 (fr) 1978-08-04
JPS5388331A (en) 1978-08-03
DE2800781A1 (de) 1978-07-13
JPS587612B2 (ja) 1983-02-10
FR2376868B1 (cg-RX-API-DMAC7.html) 1981-05-22

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