JPS5366442A - Antitumors - Google Patents

Antitumors

Info

Publication number
JPS5366442A
JPS5366442A JP13914376A JP13914376A JPS5366442A JP S5366442 A JPS5366442 A JP S5366442A JP 13914376 A JP13914376 A JP 13914376A JP 13914376 A JP13914376 A JP 13914376A JP S5366442 A JPS5366442 A JP S5366442A
Authority
JP
Japan
Prior art keywords
antitumors
derivs
glucan
cooh
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13914376A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6152125B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Takuma Sasaki
Yukio Sugino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP13914376A priority Critical patent/JPS5366442A/ja
Priority to CH1333477A priority patent/CH634855A5/fr
Priority to GB45783/77A priority patent/GB1595596A/en
Priority to BE6046229A priority patent/BE860885A/xx
Priority to FR7734450A priority patent/FR2421617A1/fr
Priority to DK510177A priority patent/DK510177A/da
Priority to SU772543704A priority patent/SU1024011A3/ru
Priority to SE7713016A priority patent/SE432939B/xx
Priority to DE19772751570 priority patent/DE2751570A1/de
Priority to CA291,230A priority patent/CA1100951A/en
Priority to NL7712764A priority patent/NL7712764A/xx
Publication of JPS5366442A publication Critical patent/JPS5366442A/ja
Priority to FR7931574A priority patent/FR2438056A1/fr
Priority to CA344,027A priority patent/CA1094453A/en
Priority to US06/224,890 priority patent/US4454315A/en
Publication of JPS6152125B2 publication Critical patent/JPS6152125B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP13914376A 1976-11-18 1976-11-18 Antitumors Granted JPS5366442A (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
JP13914376A JPS5366442A (en) 1976-11-18 1976-11-18 Antitumors
CH1333477A CH634855A5 (fr) 1976-11-18 1977-11-02 Procede de production de nouveaux derives de beta-1,3-glucanes.
GB45783/77A GB1595596A (en) 1976-11-18 1977-11-03 Glucon derivatives
BE6046229A BE860885A (fr) 1976-11-18 1977-11-16 Nouveaux medicaments antitumoraux de type beta (1 - 3) glucane
FR7734450A FR2421617A1 (fr) 1976-11-18 1977-11-16 Nouveaux medicaments antitumoraux de type b(1 3)glucane
SE7713016A SE432939B (sv) 1976-11-18 1977-11-17 Forfarande for framstellning av nya derivat av beta-1,3-glukan med farmakologisk verkan
SU772543704A SU1024011A3 (ru) 1976-11-18 1977-11-17 Способ получени карбоксиметилированных @ -1,3-глюканов
DK510177A DK510177A (da) 1976-11-18 1977-11-17 Behandling af tumorer og hidtil ukendte derivater af beta-1,3-glucan
DE19772751570 DE2751570A1 (de) 1976-11-18 1977-11-18 Carboxymethylierte beta-1,3-glucane, verfahren zu deren herstellung und antitumormittel
CA291,230A CA1100951A (en) 1976-11-18 1977-11-18 TREATMENT OF TUMORS AND NEW DERIVATIVES OF .beta.-1,3- GLUCAN
NL7712764A NL7712764A (nl) 1976-11-18 1977-11-18 Werkwijze voor de bereiding van een tumorwerend preparaat.
FR7931574A FR2438056A1 (fr) 1976-11-18 1979-12-24 Nouveaux derives carboxymethyles de type b(1 3)glucane
CA344,027A CA1094453A (en) 1976-11-18 1980-01-21 TREATMENT OF TUMORS AND NEW DERIVATIVES OF .beta.-1,3- GLUCAN
US06/224,890 US4454315A (en) 1976-11-18 1981-01-14 Carboxymethylated derivatives of β-1,3-glucan

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13914376A JPS5366442A (en) 1976-11-18 1976-11-18 Antitumors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP1417486A Division JPS61241301A (ja) 1986-01-24 1986-01-24 抗腫瘍剤

Publications (2)

Publication Number Publication Date
JPS5366442A true JPS5366442A (en) 1978-06-13
JPS6152125B2 JPS6152125B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-11-12

Family

ID=15238550

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13914376A Granted JPS5366442A (en) 1976-11-18 1976-11-18 Antitumors

Country Status (12)

Country Link
US (1) US4454315A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5366442A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE860885A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1100951A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH634855A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2751570A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK510177A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (2) FR2421617A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1595596A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7712764A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE432939B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU1024011A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039155A1 (fr) * 1995-06-05 1996-12-12 Tayca Corporation Immunostimulant
WO1997000687A1 (fr) * 1995-06-22 1997-01-09 Tayca Corporation Immunostimulant

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8404299D0 (en) * 1984-02-18 1984-03-21 Milner Research Ireland Ltd Peritoneal dialysis
US4774093A (en) * 1985-06-25 1988-09-27 Fmc Corporation Polysaccharide compositions, preparation and uses
JPH0653764B2 (ja) * 1985-07-31 1994-07-20 三井東圧化学株式会社 モノシアロガングリオシドの製造法
JPH0692441B2 (ja) * 1986-03-03 1994-11-16 株式会社林原生物化学研究所 β−Ｄ−グルカンとその製造方法及び用途
JPH02124902A (ja) * 1988-07-21 1990-05-14 Takeda Chem Ind Ltd 血液凝固抑制剤
KR0141685B1 (ko) * 1988-09-01 1998-07-01 야마따니 와따루 참게 아메보사이트 라이세이트 g 인자 활성화 저해제
CA1328074C (en) * 1988-09-01 1994-03-29 Shigenori Tanaka Horseshoe crab amebocyte lysate factor g inhibitor
DE3929355A1 (de) * 1989-09-04 1991-03-07 Boehringer Mannheim Gmbh Verfahren zur spezifischen bestimmung von pankreas-(alpha)-amylase
US5227372A (en) * 1990-03-07 1993-07-13 Children's Medical Center Corporation Method for retaining ophthalmological agents in ocular tissues
JP3122454B2 (ja) * 1990-09-27 2001-01-09 生化学工業株式会社 カブトガニ・アメボサイト・ライセートの調製法
WO1992014759A1 (en) * 1991-02-21 1992-09-03 Drug Delivery System Institute, Ltd. Carboxymethylmannoglucan and derivative thereof
US5519009A (en) * 1993-10-01 1996-05-21 Donzis; Byron A. Solubilized yeast glucan
DE59711933D1 (de) * 1996-07-19 2004-10-28 Mibelle Ag Cosmetics Polymere Glucanäther-Derivate, ihre Herstellung sowie ihre Verwendung
CN1272024C (zh) * 1999-07-09 2006-08-30 太阳农场股份有限公司 使用食物添加剂制备治疗恶性肿瘤和病毒感染以及增进免疫功能的药剂的用途
EP1414865B1 (en) * 2000-08-03 2014-04-09 Abac R & D Ag Isolation of glucan particles and uses thereof
WO2004087121A2 (en) * 2003-03-28 2004-10-14 Azaya Therapeutics, Inc. Water soluble formulations of digitalis glycosides for treating cell-proliferative and other diseases
US20050022258A1 (en) * 2003-04-25 2005-01-27 Zheng Cui Genetically determined mouse model of resistance to transplantable cancers
BRPI0611535B1 (pt) 2005-05-05 2021-11-30 Sensient Flavors Inc Método para processar células de levedura para produzir beta-glucanos e mananas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3301848A (en) * 1962-10-30 1967-01-31 Pillsbury Co Polysaccharides and methods for production thereof
US3396082A (en) * 1965-06-09 1968-08-06 Agriculture Usa Glucan production by fermentation of fleshy fungi
US3856775A (en) * 1969-07-14 1974-12-24 Ajinomoto Kk {62 -(1{43 3)-glucans
US3754925A (en) * 1970-03-24 1973-08-28 Takeda Chemical Industries Ltd New thermo gelable polysaccharide containing foodstuffs
US3987166A (en) * 1970-05-13 1976-10-19 Kaken Kagaku Kabushiki Kaisha Treatment of tumors with glucan compositions in mice and rats
JPS4837590B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1970-10-19 1973-11-12

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039155A1 (fr) * 1995-06-05 1996-12-12 Tayca Corporation Immunostimulant
WO1997000687A1 (fr) * 1995-06-22 1997-01-09 Tayca Corporation Immunostimulant

Also Published As

Publication number Publication date
GB1595596A (en) 1981-08-12
SE7713016L (sv) 1978-05-19
US4454315A (en) 1984-06-12
FR2438056B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-10-21
BE860885A (fr) 1978-05-16
NL7712764A (nl) 1978-05-22
JPS6152125B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-11-12
DK510177A (da) 1978-05-19
CA1100951A (en) 1981-05-12
FR2421617B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-12-23
FR2421617A1 (fr) 1979-11-02
SU1024011A3 (ru) 1983-06-15
CH634855A5 (fr) 1983-02-28
FR2438056A1 (fr) 1980-04-30
SE432939B (sv) 1984-04-30
DE2751570A1 (de) 1978-05-24

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