JPS525764A - Production of pyrrolidone - Google Patents
Production of pyrrolidoneInfo
- Publication number
- JPS525764A JPS525764A JP51075954A JP7595476A JPS525764A JP S525764 A JPS525764 A JP S525764A JP 51075954 A JP51075954 A JP 51075954A JP 7595476 A JP7595476 A JP 7595476A JP S525764 A JPS525764 A JP S525764A
- Authority
- JP
- Japan
- Prior art keywords
- pyrrolidone
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19752528664 DE2528664A1 (de) | 1975-06-27 | 1975-06-27 | Pyrrolidone und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS525764A true JPS525764A (en) | 1977-01-17 |
Family
ID=5950059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51075954A Pending JPS525764A (en) | 1975-06-27 | 1976-06-26 | Production of pyrrolidone |
Country Status (14)
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002024647A1 (fr) * | 2000-09-21 | 2002-03-28 | Ono Pharmaceutical Co., Ltd. | Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine |
JP2011116768A (ja) * | 2002-05-14 | 2011-06-16 | Allergan Inc | 眼圧降下剤としての8−アザプロスタグランジン類似体 |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE423813B (sv) * | 1976-08-06 | 1982-06-07 | Pfizer | Forfarande for framstellning av 1,5-disubstituerade pyrrolidoner med terapeutiska egenskaper |
US4772601A (en) * | 1988-01-25 | 1988-09-20 | Hoechst-Roussel Pharmaceuticals, Inc. | 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use |
CN1413190A (zh) * | 1999-12-22 | 2003-04-23 | 辉瑞产品公司 | 治疗骨质疏松的ep4受体选择性激动剂 |
PT1339678E (pt) | 2000-11-27 | 2007-11-30 | Pfizer Prod Inc | Agonistas selectivos do receptor ep4 no tratamento de osteoporose |
RU2288913C2 (ru) | 2001-07-16 | 2006-12-10 | Ф.Хоффманн-Ля Рош Аг | Аналоги простагландинов, способ их получения и фармацевтическая композиция, обладающая селективной агонистической активностью в отношении рецептора ep4 |
JP4211605B2 (ja) | 2001-07-16 | 2009-01-21 | 小野薬品工業株式会社 | プロスタノイドアゴニストとしての2ピロリドン誘導体 |
IL159996A0 (en) | 2001-07-23 | 2004-06-20 | Ono Pharmaceutical Co | Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient |
EP1487437B1 (en) * | 2002-03-18 | 2006-08-16 | Pfizer Products Inc. | Use of selective ep4 receptor agonists for the treatment of diseases |
JP2006515015A (ja) | 2003-01-10 | 2006-05-18 | エフ.ホフマン−ラ ロシュ アーゲー | プロスタグランジンアゴニストとしての2−ピペリドン誘導体 |
US7179820B2 (en) | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
CA2879507A1 (en) | 2012-07-19 | 2014-01-23 | Cayman Chemical Company, Inc. | Difluorolactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated disease and conditions |
US9914725B2 (en) | 2013-03-15 | 2018-03-13 | Cayman Chemical Company, Inc. | Methods of synthesizing a difluorolactam analog |
US9676712B2 (en) | 2013-03-15 | 2017-06-13 | Cayman Chemical Company, Inc. | Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions |
ES2635635T3 (es) | 2013-03-15 | 2017-10-04 | Cayman Chemical Company, Incorporated | Compuestos de difluorolactama como agonistas selectivos del receptor EP4 para su uso en el tratamiento de enfermedades y afecciones mediadas por EP4 |
AU2014290512A1 (en) | 2013-07-19 | 2015-11-12 | Cayman Chemical Company, Inc. | Methods, systems, and compositions for promoting bone growth |
-
1975
- 1975-06-27 DE DE19752528664 patent/DE2528664A1/de not_active Withdrawn
-
1976
- 1976-06-22 ES ES449095A patent/ES449095A1/es not_active Expired
- 1976-06-22 NL NL7606773A patent/NL7606773A/xx not_active Application Discontinuation
- 1976-06-24 CH CH809976A patent/CH623809A5/de not_active IP Right Cessation
- 1976-06-24 SE SE7607331A patent/SE7607331L/xx unknown
- 1976-06-24 LU LU75235A patent/LU75235A1/xx unknown
- 1976-06-25 DK DK287476A patent/DK287476A/da unknown
- 1976-06-25 AT AT0467976A patent/AT365575B/de active
- 1976-06-25 ZA ZA763802A patent/ZA763802B/xx unknown
- 1976-06-25 GB GB26564/76A patent/GB1553595A/en not_active Expired
- 1976-06-25 IL IL49916A patent/IL49916A0/xx unknown
- 1976-06-26 JP JP51075954A patent/JPS525764A/ja active Pending
- 1976-06-28 BE BE168390A patent/BE843505A/xx not_active IP Right Cessation
- 1976-06-28 FR FR7619563A patent/FR2316943A1/fr active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002024647A1 (fr) * | 2000-09-21 | 2002-03-28 | Ono Pharmaceutical Co., Ltd. | Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine |
JP2011116768A (ja) * | 2002-05-14 | 2011-06-16 | Allergan Inc | 眼圧降下剤としての8−アザプロスタグランジン類似体 |
Also Published As
Publication number | Publication date |
---|---|
IL49916A0 (en) | 1976-08-31 |
DK287476A (da) | 1976-12-28 |
DE2528664A1 (de) | 1977-01-13 |
CH623809A5 (en) | 1981-06-30 |
NL7606773A (nl) | 1976-12-29 |
FR2316943B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-11-03 |
SE7607331L (sv) | 1976-12-28 |
ZA763802B (en) | 1977-05-25 |
ATA467976A (de) | 1981-06-15 |
AT365575B (de) | 1982-01-25 |
FR2316943A1 (fr) | 1977-02-04 |
BE843505A (fr) | 1976-12-28 |
ES449095A1 (es) | 1977-12-16 |
GB1553595A (en) | 1979-09-26 |
LU75235A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-03-16 |
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