ES449095A1 - Procedimiento para la preparacion de pirrolidonas. - Google Patents
Procedimiento para la preparacion de pirrolidonas.Info
- Publication number
- ES449095A1 ES449095A1 ES449095A ES449095A ES449095A1 ES 449095 A1 ES449095 A1 ES 449095A1 ES 449095 A ES449095 A ES 449095A ES 449095 A ES449095 A ES 449095A ES 449095 A1 ES449095 A1 ES 449095A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- properties
- pyrrolidones
- hand
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004040 pyrrolidinones Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 230000003033 spasmogenic effect Effects 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752528664 DE2528664A1 (de) | 1975-06-27 | 1975-06-27 | Pyrrolidone und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES449095A1 true ES449095A1 (es) | 1977-12-16 |
Family
ID=5950059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES449095A Expired ES449095A1 (es) | 1975-06-27 | 1976-06-22 | Procedimiento para la preparacion de pirrolidonas. |
Country Status (14)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE423813B (sv) * | 1976-08-06 | 1982-06-07 | Pfizer | Forfarande for framstellning av 1,5-disubstituerade pyrrolidoner med terapeutiska egenskaper |
| US4772601A (en) * | 1988-01-25 | 1988-09-20 | Hoechst-Roussel Pharmaceuticals, Inc. | 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use |
| AU1293101A (en) | 1999-12-22 | 2001-07-03 | Pfizer Products Inc. | Ep4 receptor selective agonists in the treatment of osteoporosis |
| WO2002024647A1 (fr) * | 2000-09-21 | 2002-03-28 | Ono Pharmaceutical Co., Ltd. | Agonistes du recepteur de l'ep4 comprenant comme principe actif des derives de la 8-azaprostaglandine |
| EA200300379A1 (ru) | 2000-11-27 | 2003-08-28 | Пфайзер Продактс Инк. | Селективные агонисты рецептора ep4 в лечении остеопороза |
| EP1408961B1 (en) | 2001-07-16 | 2007-07-11 | F. Hoffmann-La Roche Ag | 2 pyrrolidone derivatives as prostanoid agonists |
| MXPA04000456A (es) | 2001-07-16 | 2004-03-18 | Hoffmann La Roche | Analogos de prostaglandina como agonistas del receptor ep4. |
| TWI313608B (en) | 2001-07-23 | 2009-08-21 | Ono Pharmaceutical Co | Lower bone mass treating agent containing er4 agonist as active ingredient |
| JP2005531516A (ja) * | 2002-03-18 | 2005-10-20 | ファイザー・プロダクツ・インク | 選択的ｅｐ４受容体アゴニストによる治療方法 |
| US6573294B1 (en) * | 2002-05-14 | 2003-06-03 | Allergan, Inc. | 8-azaprostaglandin analogs as agents for lowering intraocular pressure |
| BRPI0406717A (pt) | 2003-01-10 | 2005-12-20 | Hoffmann La Roche | Composto, composição farmacêutica que compreende o mesmo, método de tratamento de uma enfermidade em um mamìfero, utilização do composto e processo para a sua produção |
| US7179820B2 (en) | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
| HUE031885T2 (en) | 2012-07-19 | 2017-08-28 | Cayman Chemical Co Inc | Difluoro lactam preparations for EP4-mediated osteo-related diseases and conditions |
| WO2014144610A1 (en) * | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
| WO2014144500A2 (en) | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Methods of synthesizing a difluorolactam analog |
| EP3235817B1 (en) | 2013-03-15 | 2018-12-12 | Cayman Chemical Company, Incorporated | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
| CA2910398A1 (en) | 2013-07-19 | 2015-01-22 | Cayman Chemical Company, Inc. | Methods, systems, and compositions for promoting bone growth |
-
1975
- 1975-06-27 DE DE19752528664 patent/DE2528664A1/de not_active Withdrawn
-
1976
- 1976-06-22 ES ES449095A patent/ES449095A1/es not_active Expired
- 1976-06-22 NL NL7606773A patent/NL7606773A/xx not_active Application Discontinuation
- 1976-06-24 CH CH809976A patent/CH623809A5/de not_active IP Right Cessation
- 1976-06-24 SE SE7607331A patent/SE7607331L/xx unknown
- 1976-06-24 LU LU75235A patent/LU75235A1/xx unknown
- 1976-06-25 ZA ZA763802A patent/ZA763802B/xx unknown
- 1976-06-25 DK DK287476A patent/DK287476A/da unknown
- 1976-06-25 GB GB26564/76A patent/GB1553595A/en not_active Expired
- 1976-06-25 AT AT0467976A patent/AT365575B/de active
- 1976-06-25 IL IL49916A patent/IL49916A0/xx unknown
- 1976-06-26 JP JP51075954A patent/JPS525764A/ja active Pending
- 1976-06-28 FR FR7619563A patent/FR2316943A1/fr active Granted
- 1976-06-28 BE BE168390A patent/BE843505A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL49916A0 (en) | 1976-08-31 |
| SE7607331L (sv) | 1976-12-28 |
| DK287476A (da) | 1976-12-28 |
| ATA467976A (de) | 1981-06-15 |
| JPS525764A (en) | 1977-01-17 |
| GB1553595A (en) | 1979-09-26 |
| FR2316943B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-11-03 |
| DE2528664A1 (de) | 1977-01-13 |
| FR2316943A1 (fr) | 1977-02-04 |
| ZA763802B (en) | 1977-05-25 |
| CH623809A5 (en) | 1981-06-30 |
| NL7606773A (nl) | 1976-12-29 |
| LU75235A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-03-16 |
| AT365575B (de) | 1982-01-25 |
| BE843505A (fr) | 1976-12-28 |
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