JPS5225722A - Reactive asymmetric dicarboxylate* preparation and reagent for heart glycoside test containing these - Google Patents

Reactive asymmetric dicarboxylate* preparation and reagent for heart glycoside test containing these

Info

Publication number
JPS5225722A
JPS5225722A JP51099563A JP9956376A JPS5225722A JP S5225722 A JPS5225722 A JP S5225722A JP 51099563 A JP51099563 A JP 51099563A JP 9956376 A JP9956376 A JP 9956376A JP S5225722 A JPS5225722 A JP S5225722A
Authority
JP
Japan
Prior art keywords
dicarboxylate
reagent
preparation
test containing
asymmetric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51099563A
Other languages
English (en)
Other versions
JPS5855160B2 (ja
Inventor
Georuku Batsutsu Hansu
Rarufu Rinke Hansu
Shiyuterunaa Kurausu
Buaiman Giyuntaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of JPS5225722A publication Critical patent/JPS5225722A/ja
Publication of JPS5855160B2 publication Critical patent/JPS5855160B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/822—Identified hapten
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP51099563A 1975-08-20 1976-08-20 反応性非対称ジカルボン酸エステル、その製造法、および該反応生成物を含有する心臓グリコシド検査用試薬 Expired JPS5855160B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2537129A DE2537129C3 (de) 1975-08-20 1975-08-20 Reaktive unsymmetrische, einen Digoxin- bzw. Digitoxinrest enthaltende Dicarbonsäureester, Verfahren zu deren Herstellung sowie ihre Verwendung zur Herstellung von Testreagentien

Publications (2)

Publication Number Publication Date
JPS5225722A true JPS5225722A (en) 1977-02-25
JPS5855160B2 JPS5855160B2 (ja) 1983-12-08

Family

ID=5954435

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51099563A Expired JPS5855160B2 (ja) 1975-08-20 1976-08-20 反応性非対称ジカルボン酸エステル、その製造法、および該反応生成物を含有する心臓グリコシド検査用試薬

Country Status (9)

Country Link
US (3) US4133949A (ja)
JP (1) JPS5855160B2 (ja)
AT (1) AT350040B (ja)
CH (2) CH630613A5 (ja)
DE (1) DE2537129C3 (ja)
FR (1) FR2321475A1 (ja)
GB (2) GB1518054A (ja)
IT (1) IT1064727B (ja)
NL (1) NL171989C (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2537129C3 (de) 1975-08-20 1978-05-03 Boehringer Mannheim Gmbh, 6800 Mannheim Reaktive unsymmetrische, einen Digoxin- bzw. Digitoxinrest enthaltende Dicarbonsäureester, Verfahren zu deren Herstellung sowie ihre Verwendung zur Herstellung von Testreagentien
DE2862449D1 (en) * 1977-08-22 1984-11-22 Nat Res Dev Macromolecular covalent conjugates, methods for preparing and pharmaceutical compositions containing them
US4443621A (en) * 1983-03-14 1984-04-17 Pfizer Inc. p-Nitrophenyl 3-bromo-2,2-diethoxy-propionate and synthetic utility therefor
FR2574075B1 (fr) * 1984-12-04 1987-09-18 Poudres & Explosifs Ste Nale Procede de synthese d'esters actifs d'acides carboxyliques, nouveaux carbonates alpha-halogenes utiles pour cette synthese et leur mode d'obtention

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1668723A1 (de) * 1966-09-16 1971-04-08 Toyo Jozo Kk Verfahren zum Herstellen von Verbindungen mit Saeureamid-Bindung
US3953431A (en) 1971-05-24 1976-04-27 Becton, Dickinson & Company Derivatives of digoxigenin
US3997525A (en) 1974-01-16 1976-12-14 Bio-Tec, Inc. Tetra-125 iodo-di-tyramine of digitalis derivative and process for making the same
US3963697A (en) * 1974-08-29 1976-06-15 Curtis Nuclear Corporation Labelled cardiotonic glycosides for use in radioimmunoassay
US3981982A (en) 1974-09-11 1976-09-21 Abbott Laboratories Radioimmunoassay for determining the digoxin content of a sample
DE2537129C3 (de) 1975-08-20 1978-05-03 Boehringer Mannheim Gmbh, 6800 Mannheim Reaktive unsymmetrische, einen Digoxin- bzw. Digitoxinrest enthaltende Dicarbonsäureester, Verfahren zu deren Herstellung sowie ihre Verwendung zur Herstellung von Testreagentien
US4115539A (en) 1976-05-17 1978-09-19 Union Carbide Corporation Analytical or clinical derivatives, tagged derivatives and methods of analysis using such derivatives
US4221725A (en) 1977-08-12 1980-09-09 E. R. Squibb & Sons, Inc. Steroid derivatives and their use in radioimmunoassays

Also Published As

Publication number Publication date
IT1064727B (it) 1985-02-25
FR2321475B1 (ja) 1982-06-18
US4282151A (en) 1981-08-04
GB1518054A (en) 1978-07-19
US4133949A (en) 1979-01-09
CH637659A5 (de) 1983-08-15
NL171989B (nl) 1983-01-17
AT350040B (de) 1979-05-10
GB1518055A (en) 1978-07-19
CH630613A5 (de) 1982-06-30
ATA433376A (de) 1978-10-15
US4436828A (en) 1984-03-13
NL171989C (nl) 1983-06-16
FR2321475A1 (fr) 1977-03-18
DE2537129A1 (de) 1977-02-24
DE2537129B2 (de) 1977-09-29
NL7609014A (nl) 1977-02-22
JPS5855160B2 (ja) 1983-12-08
DE2537129C3 (de) 1978-05-03

Similar Documents

Publication Publication Date Title
AU501465B2 (en) Liquid sample preparation
JPS5325489A (en) Phhindicating composition and process for its preparation
JPS51133217A (en) Glucoryranosidee1*66mannitol * its preparation and utilizing same as sugar substitute
ZA756918B (en) Vessel examination system
JPS5264187A (en) Needle for analyzing blood
IL50019A0 (en) New benzylidene derivatives,their preparation and pharmaceutical compositions containing them
GB1547846A (en) Composition and test strip for the detection of occult blood
JPS5242869A (en) Glycoside compound and preparation thereof
JPS51149304A (en) Liquid modifying composition
GB1549752A (en) Substituted nitroaminophenols process for their preparation and dyeing compositions containing them
PH20356A (en) Stable solutions and process for their preparation
JPS51122479A (en) Double crystal scintilation probe
JPS5267387A (en) Dilution of liquid samples
PH13311A (en) Dyeing process and compositions for use therein
JPS5225722A (en) Reactive asymmetric dicarboxylate* preparation and reagent for heart glycoside test containing these
IL50981A (en) 17-esterified 17 -ethynyl or 17 -acetyl steroids, their preparation and pharmalceutical compositions containing them
JPS52144629A (en) Magnesiummcontaining complex* preparation of same and composition containing same
CH609721A5 (en) Liquid reactive dyestuff preparations
JPS51118756A (en) Novel steroids * pharmaceutical composition containing same and preparation thereof
JPS5277081A (en) Pfnicillins process for preparing same and medical composition containing same
GB1531301A (en) N-aralkyl-2-amino-propanamides methods for their preparation and compositions containing them
JPS527419A (en) Heterocolloidal deblicin containing medical composition and its preparation
GB1548686A (en) Colour gradient analyzer
ZA764880B (en) Blood cell typing and compatibility test procedure
ZA763779B (en) New pentacyclic derivatives their preparation and compositions containing same