JPS5077360A - - Google Patents

Info

Publication number
JPS5077360A
JPS5077360A JP49129059A JP12905974A JPS5077360A JP S5077360 A JPS5077360 A JP S5077360A JP 49129059 A JP49129059 A JP 49129059A JP 12905974 A JP12905974 A JP 12905974A JP S5077360 A JPS5077360 A JP S5077360A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP49129059A
Other languages
Japanese (ja)
Other versions
JPS5438098B2 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5077360A publication Critical patent/JPS5077360A/ja
Publication of JPS5438098B2 publication Critical patent/JPS5438098B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
JP12905974A 1973-11-12 1974-11-11 Expired JPS5438098B2 (https=)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US415186A US3887545A (en) 1973-11-12 1973-11-12 Synthesis of 1{60 -hydroxylated cholesterol derivatives

Publications (2)

Publication Number Publication Date
JPS5077360A true JPS5077360A (https=) 1975-06-24
JPS5438098B2 JPS5438098B2 (https=) 1979-11-19

Family

ID=23644712

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12905974A Expired JPS5438098B2 (https=) 1973-11-12 1974-11-11

Country Status (9)

Country Link
US (1) US3887545A (https=)
JP (1) JPS5438098B2 (https=)
AT (1) AT342793B (https=)
BE (1) BE821983A (https=)
CH (1) CH599247A5 (https=)
DE (1) DE2453648C3 (https=)
FR (1) FR2250764B1 (https=)
GB (1) GB1443680A (https=)
NL (1) NL7414675A (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5572200A (en) * 1978-11-17 1980-05-30 Hoffmann La Roche Novel manufacture of 1 alpha*3 betaadihydroxyydelta55steroid

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4264512A (en) * 1975-09-29 1981-04-28 The Regents Of The University Of California 3-Deoxy-1α-hydroxy- and 3-deoxy-1α,25-dihydroxycholecalciferol and processes for the preparation thereof
JPS603045B2 (ja) * 1976-04-19 1985-01-25 中外製薬株式会社 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法
US4098801A (en) * 1977-01-26 1978-07-04 Hoffmann-La Roche Inc. Synthesis of 1α-hydroxylated derivatives of cholesterol
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4217279A (en) * 1978-12-18 1980-08-12 Kaiser Emil T Synthesis of steroids
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
HUP9904616A3 (en) 1996-12-20 2001-02-28 Novo Nordisk As Meiosis regulating cholestane-derivatives
IL146223A0 (en) * 1999-04-30 2002-07-25 Arch Dev Corp Steroid derivatives
JP2005508281A (ja) * 2001-02-08 2005-03-31 ザ ユニバーシティー オブ シカゴ ステロイド誘導体
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
AU2003228485A1 (en) * 2002-04-12 2003-10-27 The University Of Chicago Farnesoid x-activated receptor agonists
US7897588B2 (en) * 2002-08-29 2011-03-01 The Regents Of The University Of California Agents and methods for enhancing bone formation
US9532994B2 (en) * 2003-08-29 2017-01-03 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
DE502006002752D1 (de) * 2005-04-23 2009-03-19 Ixetic Mac Gmbh Axialkolbenmaschine
CA2621157A1 (en) * 2005-09-02 2007-03-08 The Regents Of The University Of California Osteogenic and anti-adipogenic oxysterols
US9670244B2 (en) * 2006-02-27 2017-06-06 The Regents Of The University Of California Oxysterol compounds and the hedgehog pathway
US20100048944A1 (en) * 2006-07-19 2010-02-25 Farhad Parhami Interactions of hedgehog and liver x receptor signaling pathways
AU2007339325A1 (en) 2006-12-19 2008-07-10 The Regents Of The University Of California Inhibition of PPAR gamma expression by specific osteogenic oxysterols
WO2009073186A1 (en) * 2007-12-03 2009-06-11 The Regents Of The University Of California Oxsterols for activation of hedgehog signaling, osteoinduction, antiadipogenesis, and wnt signaling
US20100112030A1 (en) * 2007-03-16 2010-05-06 The Regents Of The University Of California Role of hedgehog signaling in atherosclerosis and cardiovascular disease
EP2459581A4 (en) * 2009-07-29 2012-12-26 Univ Chicago LIVER X-RECEPTOR AGONISTS
KR20150013232A (ko) 2012-05-07 2015-02-04 더 리전트 오브 더 유니버시티 오브 캘리포니아 골형성 및 헤지호그 신호전달을 유도하고 지방생성을 억제하는 옥시스테롤 유사체 oxy133
CN105263500A (zh) 2013-05-02 2016-01-20 加利福尼亚大学董事会 骨选择性成骨性氧固醇-骨靶向剂
CN114315947B (zh) * 2021-11-17 2023-10-03 王涛 一种由22-甾醇作为原料合成胆固醇和25-羟基胆固醇的新方法
CN116789726A (zh) * 2022-01-28 2023-09-22 珂阑(上海)医药科技有限公司 甾类化合物、其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080937A (en) * 1960-11-07 1963-03-12 Garbell Res Foundation Combined acoustic wall and exhaust gas deflector in operation of jet engines
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5572200A (en) * 1978-11-17 1980-05-30 Hoffmann La Roche Novel manufacture of 1 alpha*3 betaadihydroxyydelta55steroid

Also Published As

Publication number Publication date
AT342793B (de) 1978-04-25
DE2453648A1 (de) 1975-05-15
FR2250764B1 (https=) 1979-08-03
ATA899274A (de) 1977-08-15
FR2250764A1 (https=) 1975-06-06
CH599247A5 (https=) 1978-05-31
US3887545A (en) 1975-06-03
NL7414675A (nl) 1975-05-14
GB1443680A (en) 1976-07-21
BE821983A (fr) 1975-05-09
DE2453648B2 (de) 1980-06-26
JPS5438098B2 (https=) 1979-11-19
DE2453648C3 (de) 1981-08-06

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