JPS4831118B1 - - Google Patents

Info

Publication number
JPS4831118B1
JPS4831118B1 JP5552970A JP5552970A JPS4831118B1 JP S4831118 B1 JPS4831118 B1 JP S4831118B1 JP 5552970 A JP5552970 A JP 5552970A JP 5552970 A JP5552970 A JP 5552970A JP S4831118 B1 JPS4831118 B1 JP S4831118B1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5552970A
Other languages
Japanese (ja)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP5552970A priority Critical patent/JPS4831118B1/ja
Priority to CH1648473A priority patent/CH549033A/de
Priority to HUSU000745 priority patent/HU163792B/hu
Priority to DK35571AA priority patent/DK134018B/da
Priority to FI710234A priority patent/FI52081C/fi
Priority to AT352672A priority patent/AT306733B/de
Priority to NO300/71A priority patent/NO131031C/no
Priority to FR7103060A priority patent/FR2081482B1/fr
Priority to DE19712166473 priority patent/DE2166473A1/de
Priority to CS426571A priority patent/CS179398B2/cs
Priority to CH1089574A priority patent/CH581632A5/xx
Priority to CH144371A priority patent/CH578543A5/xx
Priority to DE19712104571 priority patent/DE2104571C3/de
Priority to BE762404A priority patent/BE762404A/xx
Priority to SE01297/71A priority patent/SE364714B/xx
Priority to ES387878A priority patent/ES387878A1/es
Priority to PL1971145964A priority patent/PL70900B1/pl
Priority to NLAANVRAGE7101382,A priority patent/NL169072C/xx
Priority to PL18373771A priority patent/PL92569B1/pl
Priority to CA104,284A priority patent/CA970368A/en
Priority to IL36121A priority patent/IL36121A/xx
Priority to GB2082771A priority patent/GB1309948A/en
Publication of JPS4831118B1 publication Critical patent/JPS4831118B1/ja
Priority to US05/497,936 priority patent/US4010154A/en
Priority to CH104576A priority patent/CH578545A5/de
Priority to US05/710,665 priority patent/US4079053A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP5552970A 1970-02-03 1970-06-24 Pending JPS4831118B1 (de)

Priority Applications (25)

Application Number Priority Date Filing Date Title
JP5552970A JPS4831118B1 (de) 1970-06-24 1970-06-24
CH1648473A CH549033A (de) 1970-02-03 1971-01-06 Verfahren zur herstellung von neuen benzodiazepinderivaten.
HUSU000745 HU163792B (de) 1970-06-24 1971-01-27
DK35571AA DK134018B (da) 1970-02-03 1971-01-27 Analogifremgangsmåde til fremstilling af 1-substituerede 1,4-benzodiazepinderivater eller salte deraf.
FI710234A FI52081C (fi) 1970-02-03 1971-01-28 Menetelmä terapeuttisesti käyttökelpoisten 1-substituoitujen 1,3-dihyd ro-2H-1,4-bentsodiatsepiini-2-onien valmistamiseksi.
AT352672A AT306733B (de) 1970-06-24 1971-01-28 Verfahren zur Herstellung von neuen Benzodiazepinen und ihren Salzen mit Säuren
NO300/71A NO131031C (de) 1970-02-03 1971-01-28
FR7103060A FR2081482B1 (de) 1970-02-03 1971-01-29
DE19712166473 DE2166473A1 (de) 1970-02-03 1971-02-01 Verfahren zur herstellung von 1,3dihydro-2h-1,4-benzodiazepin-2-onen
CS426571A CS179398B2 (en) 1970-06-24 1971-02-01 Method for production of new derivatives of l-substituted benzodiazepine
CH1089574A CH581632A5 (de) 1970-02-03 1971-02-01
CH144371A CH578543A5 (de) 1970-02-03 1971-02-01
DE19712104571 DE2104571C3 (de) 1970-02-03 1971-02-01 S-Phenyl-1,3-dihydro-2H-1,4benzodiazepin-2-one, ihre Salze und diese Verbindungen enthaltende Arzneipräparate
BE762404A BE762404A (fr) 1970-02-03 1971-02-02 Nouveaux derives de la benzodiazepine
IL36121A IL36121A (en) 1970-02-03 1971-02-02 Benzodiazepine derivatives and salts thereof,process for their preparation and pharmaceutical compositions containing the same
ES387878A ES387878A1 (es) 1970-02-03 1971-02-02 Un procedimiento para derivados de benzodiazepina y sales de los mismos.
PL1971145964A PL70900B1 (en) 1970-02-03 1971-02-02 Benzodiazepine derivatives processes for producing them and compo sitions containing them[gb1309948a]
NLAANVRAGE7101382,A NL169072C (nl) 1970-02-03 1971-02-02 Werkwijze voor het bereiden van 5-fenyl-7-halogeen-1,3-dihydro-2h-1,4-benzodiazepine-2-on-derivaten en zouten ervan, alsmede werkwijze ter bereiding van farmaceutische preparaten op basis van de aldus verkregen benzodiazepinederivaten.
PL18373771A PL92569B1 (de) 1970-06-24 1971-02-02
CA104,284A CA970368A (en) 1970-02-03 1971-02-02 Benzodiazepine derivatives
SE01297/71A SE364714B (de) 1970-02-03 1971-02-02
GB2082771A GB1309948A (en) 1970-02-03 1971-04-19 Benzodiazepine derivatives processes for producing them and compo sitions containing them
US05/497,936 US4010154A (en) 1970-02-03 1974-08-16 Benzodiazepinones
CH104576A CH578545A5 (en) 1970-06-24 1976-01-28 Cns-active 1-subst 1,4-benzodiazepin-2-ones
US05/710,665 US4079053A (en) 1970-02-03 1976-08-02 Benzodiazepine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5552970A JPS4831118B1 (de) 1970-06-24 1970-06-24

Publications (1)

Publication Number Publication Date
JPS4831118B1 true JPS4831118B1 (de) 1973-09-26

Family

ID=13001241

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5552970A Pending JPS4831118B1 (de) 1970-02-03 1970-06-24

Country Status (6)

Country Link
JP (1) JPS4831118B1 (de)
AT (1) AT306733B (de)
CH (1) CH578545A5 (de)
CS (1) CS179398B2 (de)
HU (1) HU163792B (de)
PL (1) PL92569B1 (de)

Also Published As

Publication number Publication date
CS179398B2 (en) 1977-10-31
AT306733B (de) 1973-04-25
HU163792B (de) 1973-10-27
CH578545A5 (en) 1976-08-13
PL92569B1 (de) 1977-04-30

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