JPH11514672A - Use of a combination of surfactants, chelating agents and essential oils for effective disinfection - Google Patents

Abstract

  (57) [Summary] The present invention relates to the use of a combination of a chelating agent, a surfactant, and an antimicrobial essential oil or active ingredient thereof in a composition to impart bactericidal properties to the composition.

Description

Detailed description of the invention Use of a combination of surfactants, chelating agents and essential oils for effective disinfection Technical Field The present invention relates to the disinfection and cleaning of various surfaces, including hard surfaces, or in laundry applications. It relates to antimicrobial compositions that can be used.

Background Antimicrobial compositions include substances that have bactericidal capabilities. Bactericides are generally accepted to greatly reduce or kill microorganisms present on surfaces. Although the art discloses antimicrobial compositions containing potent bactericidal substances, these substances are not fully satisfactory from an environmental and/or human safety point of view. For example, typical antiseptic agents used in antimicrobial compositions include quaternary ammonium.

Also, peracid and/or halogen releasing compounds such as hypochlorite A drawback associated with antimicrobial compositions based on potent bactericidal substances is that these substances It may damage the surfaces it comes in contact with to perform its bacteriostatic action. fact, over Such antimicrobial compositions based on acid and/or hypochlorite are suitable for hard surfaces and and fabrics, especially delicate fabrics such as silk, wool, etc. perceived by consumers to be non-existent.

SUMMARY OF THE INVENTION It is therefore an object of the present invention to We propose a method for effective disinfection using ingredients that are considered to be environmentally friendly. to provide.

For this purpose surfactants, chelating agents and antimicrobial essential oils, or It can be achieved by combining the active ingredients. In fact, surfactant Formulated with a combination of sex agents, chelating agents and antimicrobial essential oils, or their active ingredients It has been found that sterilization imparts bactericidal properties to the composition. In fact, the combination A composition comprising Provides excellent bactericidal properties to surfaces down to dilution levels.

Combining chelating agents, surfactants and essential oils, or active ingredients thereof for all types of surfaces, including hard surfaces, as well as for laundry applications It has a bactericidal effect in humans as well as in humans.

Advantages of the present invention include the wide range of strains of Gram-positive and Gram-negative bacteria. Excellent sterilization against bacterial pure varieties and even more resistant microorganisms such as fungi It is to be able to obtain sexuality.

Another advantage of the present invention is that in addition to providing bactericidal properties, good cleaning is also obtained.

Representative of the prior art are, for example, antimicrobially effective amounts of pine oil and at least one Yoro discloses a liquid for hard surfaces comprising an organic acid soluble in the oil of Patent No. EP-B-288689.

U.S. Pat. No. 5,403,587 discloses a method for disinfecting, sterilizing, and cleaning hard surfaces. An aqueous antimicrobial composition that can be used for cleaning is described. More specifically, see U.S. Pat. No. 5, 403,587 describes essential oils (0.02%-5%) that exhibit antibacterial efficacy, e.g. thyme oil, eucalyptus oil, clove oil, etc., and an aqueous solution of said essential oil in a water carrier or water comprising sufficient solubilizers or dispersants to form an aqueous dispersion disclosed is a chemical composition (pH 1-12).

Pending European Patent Application No. 96870017.9 describes hydrogen peroxide , an antibacterial essential oil, optionally a surfactant and a chelating agent. Compositions are disclosed.

None of these prior art references mention chelating agents, surfactants and antimicrobial essences. By combining oils or their active ingredients, even under dilute conditions, excellent surface It is not disclosed that it is endowed with specific bactericidal properties.

SUMMARY OF THE INVENTION The present invention employs chelating agents, surfactants and antimicrobial essential oils or combinations of active ingredients thereof in the composition to impart bactericidal properties to the composition.

DETAILED DESCRIPTION OF THE INVENTION A first essential component of the present invention is a chelating agent or mixture thereof. Chelating agents suitable for use herein are all chelating agents known to those skilled in the art, such as phosphonate chelating agents, aminocarboxylate chelating agents or other carboxylate chelating agents, or polyfunctionally substituted aromatic chelating agents or mixtures thereof. It has now been found that the use of a chelating agent in combination with a surfactant in addition to the antimicrobial essential oil or its active ingredients in the composition improves the antiseptic properties of the composition.

Such phosphonate chelating agents include etidronic acid (1 -hydroxyethylidene-bisphosphonic acid or HEDP), as well as amino acids lucylene poly(alkylene phosphonate), alkali metal ethane 1-hydroxy diphosphonate, nitrilotrimethylene phosphonate, ethylenediamine tetra Methylene phosphonate and diethylenetriamine pentamethylene phosphonate and aminophosphonate compounds including Phosphonate compounds are Various cations in their acid form or on some or all of their acid functional groups. It can be present as an on salt. Preferred phosphones for use herein The tochelating agent is diethylenetriamine pentamethylene phosphonate.

Such phosphonate chelating agents are commercially available from Monsanto under the tradename DEQUEST. ing.

Polyfunctionally substituted aromatic chelating agents are also useful in the compositions of the present invention. U.S. special No. 3,812,044, May 21, 1974, Connor et al. public to Cloth, see. A preferred compound of this type in acid form is dihydroxydisulfobenzene for example 1,2-dihydroxy-3,5-disulfobenzene.

A preferred biodegradable chelating agent for use herein is ethylenediamine N , N'-disuccinic acid, or its alkali metals, alkaline earth metals, ammonium ammonium or substituted ammonium salts, or mixtures thereof. Ethylenediamine N,N'-disuccinic acid, especially the (S,S) isomer, is disclosed in U.S. Pat. No. 4,704,23 3, Nov. 3, 1987, Hartman and Perkins. is Ethylenediamine N,N'-disuccinic acid can be obtained from, for example, Palmer Research It is commercially available from Laboratories under the tradename ssEDDS.

Suitable aminocarboxylate chelating agents for use herein include ethylene diaminetetraacetate, diethylenetriaminepentaacetate, diethyl Lentriamine pentaacetate (DTPA), N-hydroxyethylethylene diamine triacetate, nitrilotriacetate, ethylenediamine tetraplate ethylenediamine tetraproprionate, triethylenetetraamine hexa-acetate, ethanol diglycine, propylene diamine tetraacetic acid (PDTA) and methylglycine di-acetic acid (MGDA), both their acid forms , or their alkali metal, ammonium, and substituted ammonium salt forms state. Diethylenetriaminepentaacetic acid (DTPA), Propylene Diaminetetraacetic acid (PDTA) (this material is available for example from BASF to Trilon FS) (commercially available under the same name), and methylglycine di-acetic acid (MGDA) are used here. is particularly suitable for use.

Other carboxylate chelating agents used here include malonic acid, salicyl acid, glycine, aspartic acid, glutamic acid, dipicolinic acid and their derivatives conductors, or mixtures thereof.

Typically, the chelating agent or mixture thereof is present in the composition from 0.001 to 5% by weight, preferably 0.002-3% by weight, more preferably 0.002-1. 5% by weight.

A second essential component of the present invention is a surfactant or mixture thereof.

Suitable surfactants for use herein are all surfactants known to those skilled in the art. agents and may be anionic, nonionic, cationic, amphoteric and/or or zwitterionic surfactants. The surfactant is a chelating agent and and in combination with essential oils or their active ingredients on surfaces treated with them It is preferred because it gives excellent bactericidal performance. Also, the surfactant comprises the combination It also contributes to the cleaning performance of the composition consisting of.

Particularly suitable anionic surfactants for use herein include water-soluble salts or acids of the formula _ROSO3M , where R is preferably _C6 - _C24 hydrocarbyl, preferably _C10. alkyl or hydroxyalkyl, more preferably _C12 - _C18 alkyl or hydroxyalkyl, having a _-C20 alkyl component, and M is H or a cation, such as an alkali metal cation (e.g. sodium, potassium, lithium), or derived from ammonium or substituted ammonium (e.g. methyl-, dimethyl-, and trimethylammonium cations and quaternary ammonium cations such as tetramethylammonium and dimethylpiperidinium cations and alkylamines such as ethylamine, diethylamine, triethylamine quaternary ammonium cations, and mixtures thereof, etc.).

Other anionic surfactants suitable for use herein include alkyl-diphenyl-ether-sulfonates and alkyl carboxylates. Other anionic surfactants include soap salts (e.g. sodium, potassium, ammonium, and substituted ammonium salts such as mono-, di- and triethanolamine salts), _C9 - _C20 linear alkylbenzene sulfonates, _C8 - _C22 primary or secondary alkane sulfonates, _C8 - _C24 olefin sulfonates, e.g. alkaline earth metal citrates as described in British Patent No. 1,082,179; Sulfonated polycarboxylic acids prepared by sulfonation of pyrolysis products, _C8 - _C24 alkyl polyglycol ether sulfonates (containing up to 10 moles of ethylene oxide), alkyl ester sulfonates such as _{C14-16 methyl} ester sulfonate. , acylglycerol sulfonates, fatty oleylglycerol sulfates, alkylphenol ethylene oxide ether sulfates, paraffin sulfonates, alkyl phosphates, isethionates such as acyl isethionates, N-acyl taurates, alkyl succunamates and succinates, monoesters of sulfosuccinates (especially saturated and unsaturated _C12 - _C18 monoesters), diesters of sulfosuccinates (especially saturated and unsaturated _C6 - _C14 diesters), acyl sarcosinates, sulfates of alkyl polysaccharides, For example sulfates of alkyl polyglucosides (nonionic non-sulfated compounds described below), _branched chain primary alkyl sulfates, alkyl polyethoxycarboxylates such as those of the formula RO( _CH2CH2O ) _k - _CH2COO . -M ⁺ , where R is _C8 - _C22 alkyl, k is an integer from 0 to 10, and M is a cation that forms a soluble salt. Also suitable are resin acids and hydrogenated resin acids, such as rosin, hydrogenated rosin, and resin acids and hydrogenated resin acids present in or derived from tall oil. Other examples are described in "Surface Active Agents and Detergents" (Vol. I and II by Schwartz, Perry and Berch). Various such surfactants are described in U.S. Pat. No. 3,929,678, published December 30, 1975, Laughlin, et al., paragraph 23, lines 58 to Also described in paragraphs 29 and 23.

Preferred anionic surfactants for use in the compositions of the present invention are alkyl groups. Zenesulfonate, Alkyl Sulfate, Alkylalkoxylated Sulfate paraffin sulfonates, and mixtures thereof.

Amphoteric surfactants suitable for use herein include betaines and sulfobetaine surfactants, derivatives thereof or mixtures thereof . The betaine and sulfobetaine surfactants increase the permeability of bacterial cell walls bactericidal activity by facilitating the entry of other active ingredients into cells is preferred because it enhances

Furthermore, the various actions of the betaine and sulfobetaine surfactants are mild. in contact with sensitive surfaces such as delicate laundry or food and/or babies It is particularly suitable for cleaning surfaces. Betaine and sulfobetaine surfactants are It is also extremely gentle on the skin and/or surfaces to be treated.

Betaine and sulfobetaine surfactants suitable for use herein are those whose molecules contain both basic and acidic groups, which form internal salts, and which are cationic and Betaine/sulfobetaine and betaine-like detergents that provide both anionic hydrophilic groups. General examples of these detergents are described in U.S. Pat. Nos. 2,082,275, 2,702,279 and 2,255,082, incorporated herein by reference. there is Preferred betaine and sulfobetaine surfactants for the present invention have the formula (wherein R1 is an alkyl group having 1 to 24 carbon atoms, preferably 8 to 18 carbon atoms, more preferably 12 to 14 carbon atoms; R2 and R3 each have 1 to 3 carbon atoms, preferably 1; is an integer of 1 to 10, preferably 1 to 6, more preferably 1, Y is selected from the group consisting of carboxyl and sulfonyl groups, and the R1, R2 and R3 groups have a total of 14 to 24 carbon atoms. ), or mixtures thereof.

Particularly suitable betaine surfactants are C12-C18 alkyldimethylbetaines, e.g. Coconut betaine, and C10-C16 alkyl dimethyl betaine, e.g. including lauryl betaine. Coconut betaine is available from Seppic as Amonyl 265 It is marketed under trade names. Lauryl betaine is available from Albright & Wilson as an Empire n It is marketed under the trade name BB/L.

Other amphoteric surfactants suitable for use herein include amine oxides having the formula R ₁ R ₂ R ₃ NO below, where R ₁ , R ₂ and R ₃ are independently , is a saturated, substituted or unsubstituted, straight or branched chain alkyl group having 1 to 30 carbon atoms, preferably 6 to 30 carbon atoms, more preferably 10 to 20 carbon atoms, and most preferably 8 to 18 carbon atoms. Preferred amine oxides for use herein are the natural mixed C8 -C10 amine oxides and C12 -C16 amine oxides commercially available, for example, from Hoechst. Short chain amine oxides suitable for use in the present invention are amine oxides having the formula _R1R2R3NO , where _R1 is a C6- _C10 alkyl group, preferably a C8-C10 alkyl group _. and R ₂ and R ₃ are independently substituted or unsubstituted straight or branched chain alkyl groups having 1 to 4 carbon atoms, preferably 1 to 3 carbon atoms, more preferably methyl groups. R ₁ can be a saturated straight or branched chain alkyl group. Preferred short chain amine oxides for use herein are the natural mixed C8 -C10 amine oxides commercially available, for example, from Hoechst.

In a preferred embodiment of the invention, the surfactants are amine oxides and betaine or sulfobetaine surfactants, preferably the amine oxide betaine or or sulfobetaine in a weight ratio of 2:1 to 100:1, more preferably 6:1 ˜100:1. Such surfactants in the composition to use the agent system with a chelating agent and an antibacterial essential oil or its active ingredient moreover, it not only imparts effective bactericidal properties and effective cleaning performance to the composition, but also , which also imparts a gloss effect to the cleaned surface, i.e. on the cleaned surface treated with the composition The amount of coating/streaks left is minimized.

Preferred nonionic surfactants for use herein include various fatty alcohols Fatty alcohol ethoxylates, commercially available in chain lengths and degrees of ethoxylation and/or propoxylate. Indeed, such alkoxylated non The HLB value of an ionic surfactant depends on the chain length of the fatty alcohol and the alkoxylation property. Depends on quality and degree of alkoxylation. Many interfaces involving nonionic materials There are surfactant catalogs that list actives with their HLB values.

Chemical methods of making nonionic surfactants suitable for use herein include the corresponding The alcohol is condensed with the alkylene oxide in the desired proportions. Such a manufacturing method is It is well known to those skilled in the art and extensively disclosed in the field. Also here A wide variety of alkoxylated alcohols suitable for use are available from various suppliers. It is commercially available.

Particularly suitable nonionic surfactants for use herein are HLB (hydrophilic-philic oiliness balance) is less than 16, preferably less than 15, more preferably less than 12, at most is also preferably less than 10 for hydrophobic nonionic surfactants. These hydrophobic Nonionic surfactants have been found to have good grease removal properties.

Preferred hydrophobic nonionic surfactants for use in the compositions of the present invention have an HLB of less than _{16 and} have the formula RO-( _C2H4O ) _n ( _C3H6O ) _mH . wherein R is a _C6 - _C22 alkyl chain or a _C6 - _C28 alkylbenzene chain, n+m is 0-20, n is 0-15, m is 0-20, Preferably n+m is 1-15, n and m are 0.5-15, more preferably n+m is 1-10, and n and m are 0-10. Preferred R chains for use herein are _C8 - _C22 alkyl chains. Thus, a suitable hydrophobic nonionic surfactant for use herein is Dobanol® 91-2.5 (HLB=8.1, R is a mixture of C9 and _C11 alkyl chains, n is 2.5 and m is 0), or Lutensol (trade name) TO3 (HLB=8, R is a _C13 alkyl chain, n is 3 and m is 0), or Lutensol ( AO3 (HLB=8, R is a mixture of _C13 and _C15 alkyl chains, n is 3 and m is 0) or Tergitol 25L3 (HLB=7.7, R is in the range of _C12 to _C15 alkyl chain lengths, n is 3 and m is 0), or Dobanol® 23-3 (HLB = 8.1, R is _C12 and or Dobanol® 23-2 (HLB = 6.2, _R is a mixture of _C12 and _C13 alkyl chains). , n is 2 and m is 0), or Dobanol® 45-7 (HLB=11.6, R is a mixture of _C14 and _C15 alkyl chains, n is 7). , m is 0) Dobanol® 23-6.5 (HLB=11.9, R is a mixture of _C12 and _C13 alkyl chains, n is 6.5 and m is 0) , or Dobanol® 25-7 (HLB=12, R is a mixture of _C12 and _C15 alkyl chains, n is 7 and m is 0), or Dobanol® 91- 5 (HLB=11.6, R is a mixture of _C9 and _C11 alkyl chains, n is 5 and m is 0) or Dobanol® 91-6 (HLB=12.5) , R is a mixture of _C9 and _C11 alkyl chains, n is 6 and m is 0), or Dobanol® 91-8 (HLB=13.7, R is _C9 and C ₁₁ alkyl chains, n is 8 and m is 0), Dobanol® 91-10 (HLB=14.2, R is a mixture of _C9 - _C11 alkyl chains, n is 10 and m is 0), or a mixture thereof.

Preferred here are Dobanol (trade name) 91-2.5 or Lutensol (trade name) TO3 , or Lutensol (trade name) AO3, or Tergitol (trade name) 25L3, or Doban ol (trade name) 23-3, or Dobanol (trade name) 23-2, or mixtures thereof be. These Dobanol® surfactants are commercially available from SHELL. this Lutensol® surfactants are commercially available from BASF and these Tergit ol™ surfactant is commercially available from UNION CARBIDE.

Suitable zwitterionic surfactants have cationic properties on the same molecule over a relatively wide pH range. It contains both ionic and anionic hydrophilic groups. A typical cationic group is a quaternary ammonium groups, but other positively charged groups such as phosphonium, imida Zolinium and sulfonium groups can also be used. Typical anionic hydrophilic group are carboxylates and sulfonates, but other groups such as sulfate , phosphonates, etc. can also be used. General formula of preferred zwitterionic surfactant teeth R.₁N.⁺(R₂)(R₃) R_FourX^- and R₁is a hydrophobic group and R₂and R₃are each C₁~C_Fouralkyl, hi dloxyalkyl or other substituted alkyl groups to which these groups are attached , N can also form a ring structure, and R_Fouris a cationic nitrogen atom with a hydrophilic group , typically having 1 to 4 carbon atoms, such as alkylene, hydroxy a alkylene or polyalkoxy group, and X is a hydrophilic group, preferably is a carboxylate or sulfonate group. Preferred hydrophobic group R₁is carbon Alkyl groups in number from 8 to 22, preferably less than 18, more preferably less than 16 is. Hydrophobic groups are unsaturated and/or substituents and/or linking groups, such as Examples include aryl groups, amide groups, ester groups, and the like. In general, Kos Simple alkyl groups are preferred for reasons of stability and stability.

Other special zwitterionic surfactants have the general formula R.₁-C(O)-N(R₂)-(C(R₃)₂)_n-N(R₂)₂ ⁽⁺⁾-(C(R₃)₂)_n-SO₃ ^(-)or R.₁-C(O)-N(R₂)-(C(R₃)₂)_n-N(R₂)₂ ⁽⁺⁾-(C(R₃)₂)_n- COO^(-) and R₁is a hydrocarbon, e.g. having from 8 to 20 carbon atoms, preferably up to 18 carbon atoms; More preferred are alkyl groups up to 16, each R₂is a hydrogen (at the amide nitrogen if added), short chain alkyl or substituted alkyl having 1 to 4 carbon atoms; preferably methyl, ethyl, propyl, hydroxy-substituted ethyl or pro a group selected from the group consisting of the pill and mixtures thereof, preferably methyl and each R₃is selected from the group consisting of hydrogen and hydroxyl, each n being 1 to 4; preferably 2 to 3, more preferably 3, which (C(R₃)₂) is also 1 There are no more than 1 hydroxyl group. R.₁The groups may be branched and/or unsaturated. R.₂base is attached A ring structure can also be formed subsequently. Surfactants of this type are manufactured by the Sherex Company available under the trade name "Varion CAS Sulfobetaine" from_Ten~C₁₄fat a Silamidopropylene (hydroxypropylene) sulfobetaine.

Typically, the surfactant or mixture thereof is present in the composition at 0.0 of the total composition. 01 to 50% by weight, preferably 0.01 to 30% by weight, more preferably 0.1 to 10% by weight.

The third essential ingredient of the present invention is an antibacterial essential oil or its active ingredient, or A mixture.

Preferred antimicrobial essential oils for use herein are essential oils that exhibit antimicrobial activity. "Self "Active ingredient of an oil" means any ingredient of an essential oil that exhibits antimicrobial activity. the antibacterial Essential oils and their active ingredients are believed to act as protein denaturants. devil Also, the antimicrobial oil and its active ingredients are suitable for disinfecting the composition on any surface. Compounds that, when used, contribute to the safety profile of compositions comprising them It is a thing. Another advantage of the antimicrobial oils and their active ingredients is to impart fragrance to the composition without the need to add perfume. In fact, the anti Combining fungal essential oils and their active ingredients with surfactants and chelating agents due to not only excellent bactericidal properties on the surface treated with the composition, but also that surface It is safe to use, while also imparting a pleasant aroma.

Such essential oils include thyme, lemongrass, citrus, lemon, orange, anise. , Clove, Aniseed, Pineapple, Cinnamon, Geranium, Rose, Mint, Labbe under, citronella, eucalyptus, peppermint, camphor, sandalwood, rosmarin, vervain, fleagrass, lemongrass, ratanhiae, himalayan including, but not limited to, essential oils obtained from gi, and mixtures thereof isn't it. Preferred antimicrobial essential oils for use herein include thyme oil, clove oil, Cinnamon oil, geranium oil, eucalyptus oil, peppermint oil, mint oil, or a mixture of these.

The active ingredients of the essential oils used herein include thymol (as found in, for example, thyme) , eugenol (present e.g. in cinnamon and cloves), menthol ( e.g. in mint), geraniol (e.g. in geranium and rose) present), verbenone (e.g. present in vervain), eucalyptol and pinocalvone (e.g. present in eucalyptus), cedrol (e.g. castor cedar), anethole (e.g. present in anise), carvac roll, hinokitiol, berberine, ferulic acid, cinnamic acid, methyl salicyl Acids, methyl salicylate, terpineol and mixtures thereof. child Preferred essential oil actives for use herein are thymol, eugenol, verbe non, eucalyptol, terpineol, cinnamic acid, methylsalicylic acid and / or geraniol.

Thymol is commercially available eg from Aldrich and eugenol is eg from Sigma , Systems-Bioindustries (SBI)-Manheimer Inc.

Typically, the antimicrobial essential oil or its active ingredients or mixtures thereof are included in the composition at least 0.003% by weight of the total composition, preferably 0.006-10% % by weight, more preferably 0.1-4% by weight, most preferably 0.03-2% by weight , in amounts of

surfactants, chelating agents and antimicrobial essential oils or their active ingredients in the composition; The combination provides improved bactericidal properties even under highly dilute conditions. I found out that I can. "Improved bactericidal properties" means that surfactants, Combining chelating agents and antimicrobial essential oils and/or active ingredients thereof the bactericidal properties imparted by the use of only one or two of the ingredients in the composition It means that it is improved compared to the bactericidal property obtained by

Surfactants, chelating agents and antibacterial essential oils or active ingredients thereof according to the present invention By combining Ram-positive and Gram-negative bacteria such as Pseudomonas aeroginosa, and Cand Highly diluted strains against a variety of microorganisms, including fungi such as ida albicans. Excellent bactericidal properties can be obtained even when used under conditions.

The bactericidal properties of a composition can be measured by the bactericidal activity of the composition. A test method suitable for evaluating the fungicidal activity of a composition is described in European Standard, prEN 1040, CEN/TC 216 N 78, issued in November 1995 by the European Committee for Standardization, Brussel. European Standard, prEN 1040, CEN/TC 216 N 78 defines test methods and requirements for minimum fungicidal activity of fungicidal compositions. This test requires a reduction in bacterial colony forming units (cfu) from ¹⁰⁷ cfu (initial value) to ¹⁰² cfu (final level after contact with sterile product), i.e. ¹⁰⁵ reduction in viability. Pass if Compositions comprising surfactants, chelating agents and antimicrobial essential oils or their active ingredients pass this test even when used under highly diluted conditions.

The combination of ingredients according to the invention can be formulated into a composition in solid, paste or liquid form. can do. When the composition of the invention is formulated as a solid, these ingredients is mixed with a suitable solvent, typically water, before use. In liquid form, the composition The products are preferably, but not necessarily, formulated as aqueous compositions. use For convenience, liquid compositions are preferred herein.

In embodiments in which the compositions of the present invention are aqueous liquid cleaning compositions, these compositions comprise pH is preferably 12.0 or less, more preferably 1 to 10, most preferably 2 to 9. The pH of the composition may be adjusted using organic or inorganic acids, or alkalinity-imparting agents. can be adjusted according to use.

Since the combination of ingredients according to the invention provides effective bactericidal properties, A composition consisting of does not require the addition of other antimicrobial compounds. but if desired , in one embodiment of the invention, the composition comprises, as an optional component, a peracid further comprising other antimicrobial compounds such as bleach, or mixtures thereof be able to. A preferred peroxygen bleaching agent is hydrogen peroxide, or a water-soluble source thereof, or a mixture thereof.

The presence of peroxygen bleaching agents, particularly hydrogen peroxide, persulfates, etc., can affect the composition of the present invention. It is believed that it further contributes to the bactericidal properties. In fact, peroxygen bleaching is effective for microbial cells can attack vital functions, e.g., peroxygen bleaches, microbial cells It can inhibit the assembly of ribosomal units in the cytoplasm. Peroxide such as hydrogen peroxide Oxygen bleach is also a strong oxidizing agent and a hydroxyl group that attacks proteins and nucleic acids. Generates free radicals. In addition, the presence of peroxygen bleaching agents, especially hydrogen peroxide provides strong stain removal properties, e.g. for washing and hard surfaces This is especially noticeable on the way.

The hydrogen peroxide source used herein generates hydrogen peroxide when in contact with water. means all compounds. Aqueous supplies of hydrogen peroxide suitable for use herein Sources include percarbonates, persilicates, persulfates such as monopersulfates, perborates and and peroxyacids such as diperoxide decanedioic acid (DPDA), magnesium Umperphthalic acid and mixtures thereof.

Additionally, as a replacement for hydrogen peroxide and its sources, or Other types of peroxides can also be used in combination with and sources thereof. Suitable groups include , dialkyl peroxides, diacyl peroxides, preformed percarboxylic acids, organic and and inorganic peroxides and/or hydroperoxides.

The composition of the present invention may contain up to 15% by weight of the total composition, preferably 0.5-10 weight percent. %, more preferably 1-8% by weight peroxygen bleach or mixtures thereof. can be

The compositions of the present invention may contain other antimicrobial components that further contribute to the antimicrobial activity of the compositions of the present invention. can comprise minutes. Such antimicrobial ingredients include parabens, such as ethyl Ruparaben, propylparaben, methylparaben, glutaraldehyde or mixtures thereof.

The compositions of the present invention may also contain various other optional ingredients such as solvents, building blocks, etc. darkener, stabilizer, bleach activator, stain dispersant, dye transfer agent, brightener, perfume, powder dust inhibitors, enzymes, dispersants, dye transfer inhibitors, pigments, perfumes, radical scavengers and a dye.

The compositions of the present invention can be packaged in a variety of suitable detergent packaging known to those skilled in the art. can be done. The liquid compositions of the present invention are typically synthetic organic polymeric plastic materials. It is preferably packaged in a manufactured, manually operated spray dispensing container. In fact, the A spray-type metering device allows a relatively large area of the surface to be sterilized to be sprayed according to the invention. a uniform application of a liquid disinfectant composition suitable for use as a disinfectant, thereby can contribute to the bactericidal properties of Such a spray-type metering device can is particularly suitable for sterilizing

Spray-type metering devices suitable for use according to the invention are e.g. Specialty Pa Sold by ckaging Products, Inc. or Continental Sprayers, Inc. It includes a manually operated foam trigger type dispensing device. These types of dosing devices are e.g. U.S. Pat. No. 4,701,311 to Durmining et al., and which et al. also to Focarracci, U.S. Pat. No. 4,646,973 and U.S. Pat. , 538,745. Continental Sprayers, International T 8500 (trade name) sold by ional or Canyon, Northern Ireland Especially suitable for use here is a spray-type metering device such as the T 8100 (trade name) marketed by preferable. In such dispensing devices, the liquid composition is divided into fine droplets for spraying. and directed onto the surface to be treated. In fact, such a spray-type metering device In, when the user activates the pumping mechanism, the the composition being sprayed by energy communicating with the pumping mechanism Discharged through the mold dispenser head. More specifically, to the spray-type metering device In a grid, the composition collides with an obstacle, such as a grid or cone, and Impact is thus applied and the liquid composition is atomized, ie droplets are formed.

The compositions of the invention can also be in the form of wipes. "Wipe" means A disposable towel, such as a paper towel, impregnated with a light composition. Good In preferred embodiments, the wipe is impregnated with a liquid composition. Preferably , the wipes are packaged in a plastic box. An advantage of this embodiment is that the user The disinfectant composition can be used quickly outside the home, i.e. the liquid composition of the present invention can be applied. It does not need to be poured onto the surface to be treated/sterilized and dried with a cloth. That is, The type allows surface sterilization to be done in one step.

The compositions of the present invention can be applied to any surface for disinfection purposes. . "Surface" means hard surfaces such as bathrooms, kitchens, tabletops, refrigerators, etc., as well as cloth earth, It means all surfaces including clothing, carpets, etc. The set according to the invention The composition can be applied to the surfaces to be sterilized neat or in diluted form. can.

"Diluted form" means the composition to be used in liquid or solid form, the user typically up to 100 times by weight, preferably 80-30 times, more preferably It means that it can be diluted with water of 60 to 40 times.

The following examples further illustrate the invention.

EXAMPLES The following compositions were prepared by mixing the following ingredients in the following proportions (% by weight unless otherwise indicated).

DETPMP is diethylenetriamine pentamethylene phosphonate.

DTPA is diethylenetriamine pentaacetate.

Alkyl sulfates are C10 alkyl sulfates.

Betaine is commercially available from Albrught & Wilson under the trade name Empigen BB/L. It is a coalkyldimethyl betaine.

Amine oxide is N-decyldimethylamine oxide.

The compositions of the above examples are according to the invention, either neat or diluted. , can be used. For example, compositions I and VII, at a 1:50 dilution, Composition III is used at a 1:25 dilution to provide effective disinfection of surfaces to be treated. can In fact, these compositions are prEN 104 of the European Committee for Standardization. 0 Pass the exam.

──────────────────────────────────────────────────── ──── continuation of the front page (81) Designated country EP (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, L U, MC, NL, PT, SE), OA (BF, BJ, CF , CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG), AP (KE, LS, MW, SD, S Z, UG), UA (AM, AZ, BY, KG, KZ, MD , RU, TJ, TM), AL, AM, AT, AU, AZ , BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, H U, IL, IS, JP, KE, KG, KP, KR, KZ , LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, R O, RU, SD, SE, SG, SI, SK, TJ, TM , TR, TT, UA, UG, US, UZ, VN (72) Inventors Keith, Homer, Baker United States Ohio, Union, Ta Unship, Bennington, Drive, 10083

Claims (1)

[Claims] 1. Use of a combination of a chelating agent, a surfactant, and an antimicrobial essential oil or active ingredient thereof in a composition to impart bactericidal properties to the composition. 2. The chelating agent or mixture of chelating agents is present in the composition in an amount of from 0.001 to 5% by weight, preferably from 0.002 to 3% by weight, more preferably from 0.1 to 3% by weight of the total composition. The use according to claim 1, which is present in an amount of 002-1.5% by weight. 3. The surfactant or mixture of surfactants may be included in the composition in an amount of 0.1% of the total composition. Use according to claim 1 or 2, wherein it is present in an amount of from 01 to 50% by weight, preferably from 0.01 to 30% by weight, more preferably from 0.1 to 10% by weight. 4. The antimicrobial essential oil or its active ingredient, or a mixture of antimicrobial essential oil or its active ingredient, is present in the composition in at least 0.003% by weight of the total composition, preferably 0.006 to 10% by weight, more preferably 0%. 4. Use according to any of the preceding claims, wherein it is present in an amount of from 1 to 4% by weight, most preferably from 0.03 to 2% by weight. 5. Antibacterial essential oils are thyme oil, lemongrass oil, citrus oil, lemon oil, orange oil, anise oil, clove oil, aniseed oil, cinnamon oil, geranium oil, rose oil, lavender oil, citronella oil, eucalyptus oil, peppermint oil Mint oil, camphor oil, sandalwood oil, cedar oil, rosmarin oil, pine oil, black pine oil, fleagrass oil, lemongrass oil, ratanhiae oil, and mixtures thereof, preferably thyme oil, Clove oil, cinnamon oil, geranium oil, eucalyptus oil, peppermint oil, mint oil, or a mixture thereof, wherein the active ingredient of the essential oil is thymol, eugenol, menthol, carvacrol, verbenone, eucalyptol, cedrol , Anethole, pinocone, geraniol, cypress Selected from the group consisting of thiols, berberine, ferulic acid, cinnamic acid, methyl salicylic acid, methyl salicylate, terpineol and mixtures thereof, preferably thymol, eugenol, berbenone, eucalyptol, terpineol, cinnamic acid, methyl salicylic acid and 5. Use according to any one of the preceding claims, wherein the use is geraniol. 6. Wherein the chelator is selected from the group consisting of phosphonate chelators, aminocarboxylate chelators, or other carboxylate chelators, or polyfunctionally substituted aromatic chelators and mixtures thereof. Item 6. The use according to any one of Items 1 to 5. 7. When the chelating agent is etidronic acid, alkali metal ethane 1-hydroxydiphosphonate, nitrilotrimethylenephosphonate, ethylenediaminetetramethylenephosphonate, diethylenetriaminepentamethylenephosphonate, dihydroxydisulfobenzene, ethylenediamine N, N′-disuccinic acid, ethylenediaminetetraacetate, diethylenetriamine Pentaacetate, N-hydroxyethylethylenediaminetriacetate, nitrilotriacetate, ethylenediaminetetrapropionate, triethylenetetraaminehexa-acetate, ethanoldiglycine, propylenediaminetetraacetic acid, methylglycinedi-acetic acid, malonic acid, salicylic acid, glycine, asparagine Acid, glutamic acid, dipicolinic acid or their It is a compound, use according to claim 6. 8. The surfactant is selected from the group consisting of an anionic surfactant, a nonionic surfactant, a cationic surfactant, an amphoteric surfactant, a zwitterionic surfactant, and a mixture thereof. Use according to any one of claims 1 to 7. 9. The surfactant is an amphoteric surfactant or a mixture thereof, preferably of the formula (Wherein, R1 is an alkyl group having 1 to 24, preferably 8 to 18, more preferably 12 to 14 carbon atoms, R2 and R3 have 1 to 3 carbon atoms, preferably 1; Is an integer of 1 to 10, preferably 1 to 6, more preferably 1. Y is selected from the group consisting of carboxyl and sulfonyl groups, and the total number of carbon atoms of the R1, R2 and R3 groups is 14 to 24. A) a betaine or sulfobetaine surfactant, or a derivative thereof, or a mixture thereof, and / or a compound of the formula R ₁ R ₂ R ₃ NO, wherein R ₁ , R ₂ and R ₃ are independently carbon A saturated, substituted or unsubstituted, straight-chain or branched alkyl group having a number of 1 to 30, preferably 6 to 30, more preferably 10 to 20, most preferably 8 to 18) amine oxides; Or 9. Use according to claim 8, which is a mixture thereof. 10. Surfactant, wherein ROSO ₃ M (wherein, R is C ₆ -C ₂₄ hydrocarbyl, preferably an alkyl or hydroxyalkyl having a C ₁₀ -C ₂₀ alkyl component, more preferably C ₁₂ -C ₁₈ alkyl or hydroxyalkyl Wherein M is H, an alkali metal cation or ammonium or substituted ammonium) anionic surfactants, C ₉ -C ₂₀ linear alkyl benzene sulfonates, C ₈ -C ₂₂ primary or secondary alkanes 9. Use according to claim 8, which is a sulfonate, a paraffin sulfonate, or a mixture thereof. 11. The composition of claim 1, wherein the composition further comprises at least one other antimicrobial component selected from the group consisting of peroxygen bleaches, glutaraldehyde, ethyl paraben, propyl paraben, methyl paraben, and mixtures thereof. Use according to any one of 10 above.