JPH11510489A5 - - Google Patents

Info

Publication number
JPH11510489A5
JPH11510489A5 JP1997506945A JP50694597A JPH11510489A5 JP H11510489 A5 JPH11510489 A5 JP H11510489A5 JP 1997506945 A JP1997506945 A JP 1997506945A JP 50694597 A JP50694597 A JP 50694597A JP H11510489 A5 JPH11510489 A5 JP H11510489A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1997506945A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11510489A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1996/012087 external-priority patent/WO1997003939A1/en
Publication of JPH11510489A publication Critical patent/JPH11510489A/ja
Publication of JPH11510489A5 publication Critical patent/JPH11510489A5/ja
Withdrawn legal-status Critical Current

Links

JP9506945A 1995-07-21 1996-07-22 新規アミド基本カチオン性脂質 Withdrawn JPH11510489A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50580295A 1995-07-21 1995-07-21
US08/505,802 1995-07-21
PCT/US1996/012087 WO1997003939A1 (en) 1995-07-21 1996-07-22 Novel amide-based cationic lipids

Publications (2)

Publication Number Publication Date
JPH11510489A JPH11510489A (ja) 1999-09-14
JPH11510489A5 true JPH11510489A5 (enExample) 2004-09-16

Family

ID=24011908

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9506945A Withdrawn JPH11510489A (ja) 1995-07-21 1996-07-22 新規アミド基本カチオン性脂質

Country Status (7)

Country Link
US (1) US6020526A (enExample)
EP (1) EP0869937A4 (enExample)
JP (1) JPH11510489A (enExample)
AU (1) AU707947B2 (enExample)
CA (1) CA2227373A1 (enExample)
NZ (1) NZ313839A (enExample)
WO (1) WO1997003939A1 (enExample)

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JP5424887B2 (ja) 2006-11-08 2014-02-26 チョンシー ユー ペプチド及び関連化合物の経皮送達システム
CA2710713C (en) * 2007-12-27 2017-09-19 Protiva Biotherapeutics, Inc. Silencing of polo-like kinase expression using interfering rna
EP2224912B1 (en) * 2008-01-02 2016-05-11 TEKMIRA Pharmaceuticals Corporation Improved compositions and methods for the delivery of nucleic acids
JP5475753B2 (ja) 2008-04-15 2014-04-16 プロチバ バイオセラピューティクス インコーポレイティッド 核酸送達用の脂質製剤
CA2740000C (en) 2008-10-09 2017-12-12 Tekmira Pharmaceuticals Corporation Improved amino lipids and methods for the delivery of nucleic acids
EP2405921A4 (en) 2009-01-26 2013-05-22 Protiva Biotherapeutics Inc COMPOSITIONS AND METHODS FOR INACTIVATION OF APOLIPOPROTEIN C-III EXPRESSION
JP6352587B2 (ja) 2009-05-08 2018-07-11 テックフィールズ バイオケム カンパニー リミテッド ペプチド及びペプチド関連化合物の高浸透性プロドラッグ組成物
US9018187B2 (en) 2009-07-01 2015-04-28 Protiva Biotherapeutics, Inc. Cationic lipids and methods for the delivery of therapeutic agents
US8569256B2 (en) 2009-07-01 2013-10-29 Protiva Biotherapeutics, Inc. Cationic lipids and methods for the delivery of therapeutic agents
ES2613498T3 (es) 2009-07-01 2017-05-24 Protiva Biotherapeutics Inc. Nuevas formulaciones de lípidos para el suministro de agentes terapéuticos a tumores sólidos
WO2011011447A1 (en) 2009-07-20 2011-01-27 Protiva Biotherapeutics, Inc. Compositions and methods for silencing ebola virus gene expression
US8455455B1 (en) 2010-03-31 2013-06-04 Protiva Biotherapeutics, Inc. Compositions and methods for silencing genes involved in hemorrhagic fever
US9006417B2 (en) 2010-06-30 2015-04-14 Protiva Biotherapeutics, Inc. Non-liposomal systems for nucleic acid delivery
US8466122B2 (en) 2010-09-17 2013-06-18 Protiva Biotherapeutics, Inc. Trialkyl cationic lipids and methods of use thereof
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US9035039B2 (en) 2011-12-22 2015-05-19 Protiva Biotherapeutics, Inc. Compositions and methods for silencing SMAD4
JP5970439B2 (ja) * 2013-09-20 2016-08-17 チョンシー ユー ペプチド及び関連化合物の経皮送達システム
ES2931832T3 (es) 2014-06-25 2023-01-03 Acuitas Therapeutics Inc Lípidos y formulaciones de nanopartículas lipídicas novedosos para la entrega de ácidos nucleicos
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PT3313829T (pt) 2015-06-29 2024-07-08 Acuitas Therapeutics Inc Formulações de lípidos e de nanopartículas lipídicas para a administração de ácidos nucleicos
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CN108699096B (zh) * 2016-02-22 2021-11-26 赢创运营有限公司 用于头发香味保留的鼠李糖脂酰胺
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CN117098541A (zh) 2020-11-25 2023-11-21 阿卡格拉医药公司 用于递送核酸的脂质纳米粒及相关使用方法
KR20240123832A (ko) 2021-12-16 2024-08-14 아퀴타스 테라퓨틱스 인크. 지질 나노입자 제형에 사용하기 위한 지질
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WO2023232148A1 (zh) * 2022-06-02 2023-12-07 厦门赛诺邦格生物科技股份有限公司 一种含有不饱和键的氨基酸阳离子脂质
CN120737002A (zh) * 2022-06-02 2025-10-03 厦门赛诺邦格生物科技股份有限公司 一种氨基酸阳离子脂质
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US20240261223A1 (en) * 2022-12-27 2024-08-08 Sunvax Mrna Therapeutics Modular lipid compounds and two- to three-component lipid nanoparticle compositions
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US4548955A (en) * 1985-02-25 1985-10-22 Sogo Pharmaceutical Company Limited Nylon capsule responding to pH
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US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
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US5334761A (en) * 1992-08-28 1994-08-02 Life Technologies, Inc. Cationic lipids
US5777153A (en) * 1994-07-08 1998-07-07 Gilead Sciences, Inc. Cationic lipids

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